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2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

2018

IBX as a Catalyst for Dehydration of Hydroperoxides: Green Entry to α,β-Unsaturated Ketones via Oxygenative Allylic Transposition
Tetsuya Kuga, Yusuke Sasano, Yoshiharu Iwabuchi
Chem. Commun. Accepted Manuscript (DOI: 10.1039/C7CC08957K)

2017

Nazarov Cyclization Entry to Chiral Bicyclo[5.3.0]decanoid Building Blocks and Its Application to Formal Synthesis of (-)-Englerin A
Keisuke Morisaki, Yusuke Sasano, Takahiro Koseki, Takuro Shibuta, Naoki Kanoh, Wen-Hua Chiou, Yoshiharu Iwabuchi
Org. Lett. 2017, 19, 5142-5145




Substrate Recognition by a Dual Functional P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis
Akimasa Miyanaga, Ryuichi Takayanagi, Takashi Furuya, Ayano Kawamata, Tomohiro Itagaki, Yoshiharu Iwabuchi, Naoki Kanoh, Fumitaka Kudo, Tadashi Eguchi
ChemBioChem. 2017, 18, 2179-2187


A Mild Two-Step Propargylation of Aromatic Bioactive Small Molecules
Naoki Kanoh, Toshitaka Okamura, Takahiro Suzuki, Yoshiharu Iwabuchi
Org. Biomol. Chem. 2017, 15, 7190-7195.




Catalytic Oxygenative Allylic Transposition of Alkenes into Enones with an Azaadamantane-Type Oxoammonium Salt Catalyst
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
selected as Hot Paper
Chem. Eur.J. 2017, 23, 10276-10279.




Concise, Protecting-Group-Free Synthesis of (+)-Nemonapride via Eu(OTf)3-Catalyzed Aminolysis of 3,4-Epoxy Alcohol
Shun-ichiro Uesugi, Yusuke Sasano, Shogo Matsui, Naoki Kanoh, Yoshiharu Iwabuchi
Chem. Pharm. Bull. 2017, 65, 22-24.




2016

Reversibility of thia-Michael reaction of the cytotoxic C5-curcuminoid and structure-activity relationship of the bis-thiol- adducts thereof
Aki Kohyama, Michihiro Fukuda, Shunsuke Sugiyama, Hiroyuki Yamakoshi, Naoki Kanoh, Chikashi Ishioka, Hiroyuki Sh ibata and Yoshiharu Iwabuchi
Org. Biomol. Chem. 2016, 14, 10683-10687.




Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate
Naoki Kanoh, Kosuke Mano, Daisuke Saigusa, Takeo Usui, Yoshiharu Iwabuchi
Bioorg. Med. Chem. Lett. 2016, 26, 5770-5772.



Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented reactivity of Oxoammonium Salts
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
Angew. Chem. Int. Ed. 2016, 55, 13189-13194.

highlighted in SYNFORM



Asymmetric Total Synthesis of Heronamides A-C: Stereochemical Confirmation and Impact of Long-range Stereochemical Communication on the Biological Activity
Naoki Kanoh, Shunya Itoh, Kohei Fujita, Kohei Sakanishi, Ryosuke Sugiyama, Yuta Terajima, Yoshiharu Iwabuchi, Shinichi Nishimura, and Hideaki Kakeya
Chem. Eur. J. 2016, 22, 8586-8595



Photo-Cross-Linked Small-Molecule Affinity Matrix as a Tool for Target Identification of Bioactive Small Molecules
(From themed collection "Strategies for Cellular Target Identification of Natural Products”)
Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells
Tomohiro Itagaki, Ayano Kawamata, Miho Takeuchi, Keisuke Hamada, Yoshiharu Iwabuchi, Tadashi Eguchi, Fumitaka Kudo, Takeo Usui and Naoki Kanoh
J. Antibiot. 2016, 69, 287-293.


Vicenistatin induces early endosome-derived vacuole formation in mammalian cells
Yuko Nishiyama, Tomohiro Ohmichi, Sayaka Kazami, Sayaka Iwasaki, Kousuke Mano, Yoko Nagumo, Fumitaka Kudo, Sosaku Ichikawa, Yoshiharu Iwabuchi, Naoki Kanoh, Tadashi Eguchi, Hiroyuki Osada, and Takeo Usui
Biosci. Biotech. Biochem., 2016, 80, 902-910.

An enantiocontrolled entry to the tricyclic polar segment of (+)-fusarisetin A
Aki Kohyama, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
Tetrahedron Lett, 2016, 57, 517-519



Total Synthesis of the Proposed Structure of Turkiyenine
Hisataka Kobayashi, Yusuke Sasano, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
Eur. J. Org. Chem, 2016, 270-273



2015

Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B
Shun-ichiro Uesugi, Tsubasa Watanabe, Takamichi Imaizumi, Yu Ota, Keisuke Yoshida, Haruna Ebisu, Takumi Chinen, Yoko Nagumo, Masatoshi Shibuya, Naoki Kanoh, Takeo Usui, Yoshiharu Iwabuchi
J. Org. Chem, 2015, 80, 12333-12350



Structure-Activity Relationships of the Antitumor C5-Curcuminoid GO-Y030
Aki Kohyama, Hiroyuki Yamakoshi, Shoko Hongo, Naoki Kanoh, Hiroyuki Shibata, Yoshiharu Iwabuchi
Molecules, 2015, 20, 15374-15391

Irciniastatin A Induces a Potent and Sustained Activation of Extracellular Signal-regulated Kinase and Thereby Promotes Ectodomain Shedding of TNF Receptor 1 in Human Lung Carcinoma A549 Cells
Hue Tu Quach, Seiya Hirano, Tsubasa Watahabe, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui, Takao Kataoka
Biol. Pharm. Bull., 2015, 38, 941-946

化合物の標的タンパク質を検出するための技術
叶 直樹, 生体の科学
2015, 66, 156-162

標的同定の迅速化を目指した生物活性リガンドの非古典的修飾・固相 担持法
叶 直樹, CSJ カレントレビュー 19 「生物活性分子の標的同定と機能 解明―生命科学の基盤技術としてのアプローチ」
化学同人, 2015, 48-56

Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1
Seiya Hirano, Hue Tu Quach, Tsubasa Watanabe, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui, Takao Kataoka
J Antibiot, 2015, 68, 417-420.

Third Generation Photo-Cross-Linked Small-Molecule Affinity Matrix: A Photoactivatable and Photocleavable System Enabling Quantitative Analysis of the Photo-Cross-Linked Small Molecules and Their Target Purification
Takahiro Suzuki, Toshitaka Okamura, Takenori Tomohiro, Yoshiharu Iwabuchi, Naoki Kanoh
Bioconjugate Chem, 2015, 26, 389-395

Highly Efficient Aerobic Oxidation of Alcohols by Using Less-Hindered Nitroxyl-Radical/Copper Catalysis: Optimum Catalyst Combinations and Their Substrate Scope
Yusuke Sasano, Naoki Kogure, Tomohiro Nishiyama, Shota Nagasawa, Yoshiharu Iwabuchi
Chem, Asian J, 2015, 10, 1004-1009

Development of an Azanoradamantane-Type Nitroxyl Radical Catalyst for Class-Selective Oxidation of Alcohols
Ryusuke Doi, Masatoshi Shibuya, Tsukasa Murayama, Yoshihiko Yamamoto, Yoshiharu Iwabuchi
J. Org. Chem, 2015, 80, 401−413

2014

Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chiral Alkoxyamines as Precatalysts: Catalyst Structure, Active Species, and Substrate Scope
Keiichi Murakami, Yusuke Sasano, Masaki Tomizawa, Masatoshi Shibuya, Eunsang Kwon, Yoshiharu Iwabuchi
J. Am. Chem. Soc., 2014, 136, 17591-17600

Mechanistic Insight into Aerobic Alcohol Oxidation Using NOx-Nitroxide Catalysis Based on Catalyst Structure-Activity Relationships
Masatoshi Shibuya, Shota Nagasawa, Yuji Osada, Yoshiharu Iwabuchi
J. Org. Chem, 2014, 79, 10256-10268

Structure-function analyses of cytochrome P450revI involved in reveromycin A
biosynthesis and evaluation of the biological activity of its substrate,
reveromycin T
Shunji Takahashi, Shingo Nagano, Toshihiko Nogawa, Naoki Kanoh, Masakazu Uramoto, Makoto Kawatani, Yoshitsugu Shiro, Hiroyuki Osada
J. Biol. Chem. , 2014, 289, 32446-32458

A Concise and Unified Strategy for Synthesis of the C1-C18 Macrolactone Fragments of FD-891, FD-892 and Their Analogues: Formal Total Synthesis of FD-891
Naoki Kanoh, Ayano Kawamata, Tomohiro Itagaki, Yuta Miyazaki, Kenzo Yahata, Eunsang Kwon, Yoshiharu Iwabuchi
Org, Lett, 2014, 16, 5216-5219

Eu(OTf)3-Catalyzed Highly Regioselective Nucleophilic Ring Opening of 2,3-Epoxy Alcohols: An Efficient Entry to 3-Substituted 1,2-Diol Derivatives
Shun-ichiro Uesugi, Tsubasa Watanabe, Takamichi Imaizumi, Masatoshi Shibuya, Naoki Kanoh,
Yoshiharu Iwabuchi
Org, Lett, 2014, 16, 4408-4411.

Strong inhibitory effects of curcumin and its demethoxy analog on Escherichia coli ATP synthase F1 sector
Mizuki Sekiya, Eiko Chiba, Momoe Satoh, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi,
Masamitsu Futai, Mayumi Nakanishi-Matsui
International Journal of Biological Macromolecules, 2014, 40, 241-245.
Highly Chemoselective Aerobic Oxidation of Amino Alcohols into Amino Carbonyl Compounds
Yusuke Sasano, Shota Nagasawa, Mai Yamazaki, Masatoshi Shibuya, Jaiwook Park,
Yoshiharu Iwabuchi
Angew. Chem. Int. Ed., 2014, 53, 3236-3240.
Enantioselective Intramolecular Aza-Spiroannulation onto Benzofurans Using Chiral Rhodium Catalysis
Takuro Shibuta, Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, Tohru Taniguchi, Kenji Monde,
Yoshiharu Iwabuchi
Heterocycles, 2014, 89, 631-639.
Total Synthesis of the Proposed Structure of Heronamide C
Kohei Sakanishi, Shunya Itoh, Ryosuke Sugiyama, Shinichi Nishimura, Hideaki Kakeya,
Yoshiharu Iwabuchi, Naoki Kanoh
Eur. J. Org. Chem., 2014, 1376-1380.

2013

Discovery and Exploitation of AZADO: The Highly Active Catalyst for Alcohol Oxidation (Review)
An Improved Fluorogenic NAD(P)+ Detection Method Using 2-Acetylbenzofuran: Its Origin and Application
Takashi Moriya, Ayano Kawamata, Yusuke Takahashi, Yoshiharu Iwabuchi, Naoki Kanoh
Chem. Commun., 2013, 49, 11500-11502.
3-Methyl-4-Oxa-5-Azahomoadamantane: Alkoxyamine-Type Organocatalyst for Alcohol Oxidation
Yusuke Sasano, Keiichi Murakami, Tomohiro Nishiyama, Eunsang Kwon, Yoshiharu Iwabuchi
Angew. Chem. Int. Ed., 2013, 52, 12624-12627.
On the Origin of cine-Substitution in the Stille Coupling of Trisubstituted Iodoalkene and trans-Vinylstannane
Naoki Kanoh, Yutaro Ohno, Tomohiro Itagaki, Hayato Fukuda, Yoshiharu Iwabuchi
Synlett, 2013, 24, 2660-2664.
TEG scanning を用いた破骨細胞分化阻害剤メチルゲルフェリンの多次元的構造活性相関
鈴木貴大、高山 浩、川谷 誠、長田裕之、岩渕好治、叶 直樹
Chemical Biology (日本ケミカルバイオロジー学会機関紙), 2013, 6(1), 3-7
C-H MODIFICATION OF 2-AZAADAMANTANE: SYNTHESIS OF C5-FUNCTIONALIZED AZADOS FOR ADVANCED USE
Yusuke Sasano, Tomohiro Nishiyama, Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
Heterocycles, 2013, 87, 2109-2118.
有機ニトロキシルラジカルの反応性制御に基づく効率的アルコール空気酸化反応の開発
澁谷 正俊、岩渕 好治
有機合成化学協会誌 2013, 71, 515-525.
Concise Entry to Chiral 5-(4-Hydroxybutyl)-2(5H)-furanone via HTIB-Mediated Novel Oxidative Fragmentation: Formal Total Synthesis of (+)-Dubiusamine A
Muneo Kawasumi and Yoshiharu Iwabuchi
Org. Lett. 2013, 15, 1788-1790.
Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning
Naoki Kanoh, Takahiro Suzuki, Makoto Kawatani, Yasuhiro Kato, Hiroyuki Osada, Yoshiharu Iwabuchi
Bioconjugate Chem. 2013, 24, 44-52.
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2012

Nitroxyl Radical/PhI(OAc)2: One-Pot Oxidative Cleavage of Vicinal Diols to (Di)Carboxylic Acids
Masatoshi Shibuya, Takuro Shibuta, Hayato Fukuda, and Yoshiharu Iwabuchi
Org. Lett. 2012, 14, 5010-5013.
Organocatalytic One-Pot Oxidative Cleavage of Terminal Diols to Dehomologated Carboxylic Acids
Masatoshi Shibuya, Ryūsuke Doi, Takuro Shibuta, Shun-ichiro Uesugi, and Yoshiharu Iwabuchi
Org. Lett. 2012, 14, 5006-5009.
Synthesis and Structure-Activity Relationship of Vicenistatin, a Cytotoxic 20-Membered Macrolactam Glycoside
Hayato Fukuda, Yuko Nishiyama, Shiina Nakamura, Yutaro Ohno, Tadashi Eguchi, Yoshiharu Iwabuchi, Takeo Usui, Naoki Kanoh
Chem. Asian. J. 2012, 7, 2872-2881.
Catalytic Oxidation of Silyl Enol Ethers to 1,2-Diketones Employing Nitroxyl Radicals
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
Synlett 2012, 1025-1031.
Oxidation of Alcohols to Carbonyl Compounds with Diisopropyl Azodicarboxylate Catalyzed by Nitroxyl Radicals
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
J. Org. Chem. 2012, 77, 3005-3009
Oxidation of Nitroxyl Radicals: Electrochemical and Computational Studies
Masatoshi Shibuya, Fabio Pichierri, Masaki Tomizawa, Shota Nagasawa, Iwao Suzuki, Yoshiharu Iwabuchi
Tetrahedron Lett. 2012, 53, 2070-2073.
Oxidative Conversion of Silyl Enol Ethers to α,β-Unsaturated Ketones Employing Oxoammonium Salts
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
Org. Lett. 2012, 14, 154-157.

2011

9-Azanoradamantane N-Oxyl (Nor-AZADO): A Highly Active Organocatalyst for Alcohol Oxidation
Masaki Hayashi, Yusuke Sasano, Shota Nagasawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
Chemical & Pharmaceutical Bulletin 2011, 59, 1570-1573.
Practical preparation methods for highly active azaadamantane-nitroxyl-radical-type oxidation catalysts
Masatoshi Shibuya, Yusuke Sasano, Masaki Tomizawa, Toshimasa Hamada, Masami Kozawa, Noriaki Nagahama, Yoshiharu Iwabuchi
Synthesis 2011, 3418-3425.
Novel Curcumin Analogs, GO-Y030 and GO-Y078, Are Multi-targeted Agents with Enhanced Abilities for Multiple Myeloma
Chieko Kudo, Hiroyuki Yamakoshi, Atsuko Sato, Hisatsugu Ohori, Chikashi Ishioka , Yoshiharu Iwabuchi, Hiroyuki Shibata
Cancer Science 2011, 102, 1045-1051.
Detection of cytochrome P450 substrates using a small-molecule droplet array on an NADH-immobilized solid surface
Hiroshi Takayama, Shunji Takahashi, Takashi Moriya, Hiroyuki Osada, Yoshiharu Iwabuchi, Naoki Kanoh
ChemBioChem 2011, 12, 2748-2752.
High-Performance Liquid Chromatography with Photodiode Array Detection for Determination of Nobiletin Content in the Brain and Serum of Mice Administrated the Natural Compound
Daisuke Saigusa, Masatoshi Shibuya, Daisuke Jinno, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Akihito Yokosuka, Yoshihiro Mimaki, Akira Nganuma, Yasushi Ohizumi, Yoshihisa Tomioka, Tohru Yamakuni
Anal. Bioanal. Chem. 2011, 400, 3635-3641.
Targeting Colon Cancer Stem Cells Using a New Curcumin Analogue, GO-Y030
L. Lin, Y Liu, P-K. Li, J. Fuchs, H. Shibata, Y. Iwabuchi, and J. Lin
British J. Cancer 2011, 105, 212-220.
Synthesis of 86 Species of 1,5-Diaryl-3-oxo-1,4-pentadienes Analogs of Curcumin can Yield a Good Lead in Vivo
Chieko Kudo, Hiroyuki Yamakoshi, Atsuko Sato, Hiroshi Nanjo, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiyoyuki Shibata
BMC Phamacology 2011, 11, 4.
Highly Efficient, Organocatalytic Aerobic Alcohol Oxidation
Masatoshi Shibuya, Yuji Osada, Yusuke Sasano, Masaki Tomizawa, Yoshiharu Iwabuchi
J. Am. Chem. Soc. 2011, 133, 6497-6500.
Concise Entry to Both Enantiomers of 8-Oxabicyclo[3.2.1]oct-3-en-2-one Based on Novel Oxidative Etherification: Formal Synthesis of (+)Sundiversiforide
Muneo Kawasumi, Naoki Kanoh, and Yoshiharu Iwabuchi
Org. Lett. 2011, 13, 3620-3623.
Asymmetric Total Syhthesis of (-)-Scabronine G via Intramolecular Double Michael Reaction and Prins Cyclization
Naoki Kanoh, Kohei Sakanishi, Emiko Iimori, Ken'ichi Nishimura, and Yoshiharu Iwabuchi
Org. Lett. 2011, 13, 2864-2867.
Curcumin analog GO-Y030 is a novel inhibitor of IKKβ that suppresses NF-κB signaling and induces apoptosis
Atsuko Sato, Chieko Kudo, Hiroyuki Yamakoshi, Yoshihiko Uehara, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiroyuki Shibata
Cancer Science 2011, 102, 1045-1051.
Preparation of Photo-Cross-Linked Small Molecule Affinity Matrices for Affinity Selection of Protein Targets for Biologically Active Small Molecules
Hiroshi Takayama, Takashi Moriya, Naoki Kanoh
in Chemical Genomics and Proteomics: Reviews and Protocols (Ed.: E. D. Zanders), Humana Press, Totowa, 2011, pp. 75-84.
化合物アレイを起点としたケミカルバイオロジー ~化合物アレイの基盤技術開発から機能未知タンパク質の機能解析まで~
Naoki Kanoh, Siro Simizu
化学と工業, 2011, 64(1), 37-39.
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2010

An Enantio- and Diastereocontrolled Synthesis of (-)-Salinosporamide A
Heterocycles 2010, 81, 2239-2245.
Yosuke Sato, Hayato Fukuda, Masaki Tomizawa, Tomohito Masaki, Masatoshi, Shibuya, Naoki Kanoh, and Yoshiharu Iwabuchi
KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue
Hiroyuki Yamakoshi, Naoki Kanoh, Chieko Kudo, Atsuko Sato, Kazunori Ueda, Makoto Muroi, Shunsuke Kon, Masanobu Satake, Hisatsugu Ohori, Chikashi Ishioka, Yoshiteru Oshima, Hiroyuki Osada, Natsuko Chiba, Hiroyuki Shibata, Yoshiharu Iwabuchi
ACS Med. Chem. Lett. 2010, 1, 273-276.
Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway
Toxicol. Lett. 2010, 199, 341-346.
Takumi Chinen, Yoko Nagumo, Tsubasa Watanabe, Takamichi Imaizumi, Masatoshi Shibuya, Takao Kataoka, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui
Concise Total Synthesis of Vicenistatin
Synlett 2010, 2589-2592.
Hayato Fukuda, Shiina Nakamura, Tadashi Eguchi, Yoshiharu Iwabuchi, Naoki Kanoh
Syntheses and Biological Evaluation of Irciniastatin A and the C1-C2 Alkyne Analogus
Org. Lett. 2010, 12, 1040-1043.
Tsubasa Watanabe, Takamichi Imaizumi, Takumi Chinen, Yoko Nagumo, Masatoshi Shibuya, Takeo Usui, Naoki Kanoh, and Yoshiharu Iwabuchi
Total Synthesis and Determination of the Absolute Configuration of (-)-Idesolide
Org. Lett. 2010, 12, 980-983.
Hiroyuki Yamakoshi, Masatoshi Shibuya, Masaki Tomizawa, Yuji Osada, Naoki Kanoh, and Yoshiharu Iwabuchi
Structure-Activity Relationship of C5-Curcuminoids and Synthesis of their Molecular Probes Thereof
Bioorg. Med. Chem. 2010, 18, 1083-1092.
Hiroyuki Yamakoshi, Hisatsugu Ohori, Chieko Kudo, Atsuko Sato, Naoki Kanoh, Chikashi Ishioka, Hiroyuki Shibata, and Yoshiharu Iwabuchi
Cleavable Linker for Photo-Cross-Linked Small-Molecule Affinity Matrix
Naoki Kanoh, Hiroshi Takayama, Kaori Honda, Takashi Moriya, Takayuki Teruya, Siro Simizu, Hiroyuki Osada, Yoshiharu Iwabuchi
Bioconjugate Chem. 2010, 21, 182.
光親和型小分子固定化を利用した小分子ー蛋白質間相互作用スクリーニングプラットフォーム
Naoki Kanoh
in 生命現象を理解する分子ツール ~イメージングから生体機能解析まで~ (Eds.: I. Hamachi, S. Futaki), 化学同人, Kyoto, 2010, pp. 88-94.
有機合成化学を基盤とした天然有機化合物のケミカルバイオロジー
Naoki Kanoh
J. Syn. Org. Chem., Jpn. 2010, 68, 939.
第7章 各種バイオチップ 第4節 化合物チップ
Naoki Kanoh
in バイオチップ実用化ハンドブック (Eds.: 金子周一, 堀池靖浩, 監修), NTS Inc., Tokyo, 2010, pp. 203-209.
Construction of Photo-Cross-Linked Microarrays of Small Molecules
Naoki Kanoh
in Small Molecule Microarrays: Methods and Protocols (Eds.: S. Q. Yao, M. Uttamchandani), Humana Press, Totowa, 2010, pp. 17-22.
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2009

Syntheses of Naturally Occurring Cytotoxic[7.7]paracyclophanes, (-)-Cylindrocyclophane A and its Enantiomer, and Implications for Biological Activity
Org. Biomol. Chem. 2009, 7, 3772-3781.
Hiroyuki Yamakoshi, Fumiya Ikarashi, Masataka Minami, Masatoshi Shibuya, Tsutomu Sugahara, Naoki Kanoh, Hisatsugu Ohori, Hiroyuki Shibata and Yoshiharu Iwabuchi
Highly Enantioselective Intramolecular Aza-Spiroannulation onto Indoles Using Chiral Rhodium Catalysis: Asymmetric Entry to the Spiro-β-lactam Core of Chartellines
Chem. Commun. 2009, 6264-6266.
Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, and Yoshiharu Iwabuchi
An Expedient Route to a Potent Gastrin/CCK-B Receptor Antagonist (+)-AG-041R
J. Org. Chem. 2009, 74, 7522-7524.
Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, and Yoshiharu Iwabuchi
4'-Demethylnobiletin, a Bioactive Metabolite of Nobiletin Enhancing PKA/ERK/CREB Signaling, Rescues Learning Impairment Associated with NMDA Receptor Antagonism via Stimulation of the ERK Cascade
Biochemistry. 2009, 48, 7713-7721.
Md. Al Rahim, Akira Nakajima, Daisuke Saigusa, Naomi Tetsu, Yuji Maruyama, Masatoshi Shibuya, Hiroyuki Yamakoshi, Yoshihisa Tomioka, Yoshiharu Iwabuchi, Yasushi Ohizumi, and Tohru Yamakuni
Activation of Endothlial Nitric Oxide Synthase by a Vanadium Compound Ameliorates Pressure Overload-Induced Cardiac Injury in Ovariectomized Rats
Hypertension 2009, 53, 57-63.
Md. Shenuarin Bhulyan, Norifumi Shioda, Masatoshi Shibuya, Yoshiahru Iwabuchi, and Kohji Fukunaga
An Expeditious Entry to 9-Azabicyclo[3.3.1]nonane N-Oxyl (ABNO): Another Highly Active Organocatalysts for Oxidation of Alcohols
J. Org. Chem. 2009, 74, 4619-4622.
Masatoshi Shibuya, Masaki Tomizawa, Yusuke Sasano, and Yoshiharu Iwabuchi
Synthetic Studies on Daphnicyclidin A: Enantiocontrolled Construction of the BCD Ring System
Org. Lett. 2009, 11, 1833-1836.
Shuhei Ikeda, Masatoshi Shibuya, Naoki Kanoh, and Yoshiharu Iwabuchi
Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chirally Modified AZADOs
Org. Lett. 2009, 11, 1829-1831.
Masaki Tomizawa, Masatoshi Shibuya and Yoshiharu Iwabuchi
Crrection: Org. Lett. 2014, 16, 4968-4968.

Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas
Journal of Oncology 2009, 35, 867-872.
Brian Hutzen, Lauren Friedman, Matthew Sobo, Li Lin, Ling Cen, Stephanie De Angelis, Hiroyuki Yamakoshi, Hiroyuki Shibata, Yoshiharu Iwabuchi, Jiayuh Lin
Newly Synthesized Curcumin Analog Has Improved Potential to Prevent Colorectal Carcinogenesis In Vivo
Cancer Science 2009, 100, 956-960.
Hiroyuki Shibata, Hiroyuki Yamakoshi, Atsuko Sato, Hisatsugu Ohori, Yuichi Kakudo, Chieko Kudo, Yayoi Takahashi, Mika Watanabe, Hiroshi Takano, Chikashi Ishioka, Tetsuo Noda, Yoshiharu Iwabuchi
Oxoammonium Salt/NaClO2: an Expedient, Catalytic System for One-Pot Oxidation of Primary Alcohols to Carboxylic Acids with Broad Substrate Applicability
Chem. Commun. 2009, 1739-1741.
Masatoshi Shibuya, Takahisa Sato, Masaki Tomizawa, and Yoshiharu Iwabuchi
Structure-Affinity Relationship Study of Bleomycins and Shble Protein by Use of a Chemical Array
Isao Miyazaki, Hideo Okumura, Siro Simizu, Yoshikazu Takahashi, Naoki Kanoh, Yasuhiko Muraoka, Yoshiaki Nonomura, Hiroyuki Osada
ChemBioChem 2009, 10, 845-852.
Recent Advances and Developments of Small Molecule Microarrays
Naoki Kanoh, Hiroyuki Osada
in Protein Targeting with Small Molecules: Chemical BIology Techniques and Applications (Ed.: H. Osada), Wiley, Hoboken, 2009, pp. 57-80.
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2008

Distribution of Photo-Cross-Linked Products from 3-Aryl-3-trifluoromethy ldiazirines and Alcohols
Tetrahedron 2008, 64, 5692-5698.
Naoki Kanoh, Takemichi Nakamura, Kaori Honda, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Osada
TEMPO/NaIO4-SiO2: A Catalytic Oxidative Reattangement of Tertiary Allylic Alcohols to β-Substituted α,β-Unsaturated Ketones
Org. Lett. 2008, 10, 4751-4718.
Masatoshi Shibuya, Masaki Tomizawa, and Yoshiharu Iwabuchi
Oxidative Rearrangement of Tertiary Allylic Alcohols Employing Oxoammnonium Salts
J. Org. Chem. 2008, 73, 4750-4752.
Masatoshi Shibuya, Masaki Tomizawa, and Yoshiharu Iwabuchi
Flexible Access to Monoterpenoid Indole Alkaloids Using a Cyclopentanoid Chiral Building Block
Heterocycles 2008, 77, 855-863.
Masato Hayashi, Keiichi Motosawa, Atsushi Satoh, Masatoshi Shibuya, Kunio Ogasawara, and Yoshiharu Iwabuchi
Efficient Entry to the Pyrroloquinoline Core of Martinella Alkaloids via Novel Base-catalyzed Mukaiyama-Mannich Reaction
Chem. Lett. 2008, 37, 962-963.
Shuhei Ikeda, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
Chemoenzymatic Preparation of Functionalized bicyclo[3.2.1]octenone and Practical Utilization
Tetrahedron: Asymmetry 2008, 19, 176-185.
Shinichiro Ito, Ayako Tosaka, Keisuke Hanada, Masatoshi Shibuya, Kunio Ogasawara, and Yoshiharu Iwabuchi
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I
Proc. Natl. Acad. Sci. USA 2008, 105, 11691.
Makoto Kawatani, Hideo Okumura, Kaori Honda, Naoki Kanoh, Makoto Muroi, Naoshi Dohmae, Masamichi Takami, Mitsuhiro Kitagawa, Yushi Futamura, Masaya Imoto, Hiroyuki Osada
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2007

Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression
Europian Journal of Pharmacology 2007, 571, 180-188.
Md. Shenuarin Bhuiyan, Masatoshi Shibuya, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yosiharu Iwabuchi, Kohji Fukunaga
Asymmetric Total Synthesis of Martinelline and Martinellic Acid
Chem. Commun. 2007, 504-506.
Shuhei Ikeda, Masatoshi Shibuya, and Yoshiharu Iwabuchi
Synthesis of an Enantiomeric DNA oligomer and its T-Hg(II)-T Base-pair Formation
Nucleic Acids Symposium Siries. 2007, 51, 187-188.
Kaichiro Haruta, Yoshiyuki Tanaka, Takuya Kawamura, Yoshinori Kondo, Akira Ono, Hiroyuki Yamakoshi, Naoki Kanoh, Yoshiharu Iwabuchi
Enantio- and Diastereocontrolled Synthesis of (+)-Juvabione employing Organocatalytic Desymmetrisation and Photoinduced Fragmentation
Chem. Commun. 2007, 1175-1176.
Noriaki Itagaki, Yoshiharu Iwabuchi
第10章 低分子アレイ
Siro Simizu, Isao Miyazaki, Yasumitsu Kondoh, Naoki Kanoh, Hiroyuki Osada
in マイクロアレイ・バイオチップの最新技術 (Ed.: Y. Ito), CMC press, Tokyo, 2007, pp. 229-239.
化合物アレイを用いた低分子-タンパク質相互作用の検出
Akiko Saito, Naoki Kanoh, Hiroyuki Osada
in 実験医学別冊 分子間相互作用解析ハンドブック (Ed.: 磯辺俊明、中山敬一、伊藤隆司), Yodosha, Tokyo, 2007, pp. 225-229.
第6章 小分子チップ
N. Kanoh
in ナノバイオ計測の実際 (Eds.: K. Mihara, E. Obata, Y. Baba), Kodansya Scientific, Tokyo, 2007, pp. 52-62.
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2006

Synthesis and Biological Analysis of New Curcumin Analogues Bearing and Enhanced Petential for the Medicinal Treatment of Cancer
Mol. Cancer Ther. 2006, 5, 153-159.
Hisatsugu Ohori, Hiroyuki Yamakoshi, Masaki Tomizawa, Masatoshi Shibuya, Yuikchi Kakudo, Atsuko Takahashi, Shin Takahashi, Satoshi Kato, Takao Suzuki, Chikashi Ishioka, Yoshiharu Iwabuchi, and Hiroyuki Shibata
Total Synthesis of (-)-Dihydrocorynantheol Using Bicyclo[3.2.1]octenone Chiral Building Block
Heterocycles 2006, 70, 2563-2571.
Ayako Tosaka, Shinichiro Ito, Norio Miyazawa, Masatoshi Shibuya, Kunio Ogasawra, and Yoshiharu Iwabuchi
2-Azaadamantane N-Oxyl (AZADO) and 1-Me-AZADO: Highly Efficient Organocatalysts for Oxidation of Alcohols
J. Am. Chem. Soc. 2006, 128, 8412-8413.
Masatoshi Shibuya, Masaki Tomizawa, Iwao Suzuki, Yoshiharu Iwabuchi
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2005

Expedient Synthesis of PotentCannabinoid Receptor Agonist (-)-CP55,940
Org. Lett. 2005, 7, 4181-4183.
Noriaki Itagaki,Tsutomu Sugahara, Yoshiharu Iwabuchi
Oganocatalytic Entry to Chiral Bicyclo [3.n.1] alkanones via Direct Asymmetric Intramolecular Aldolization
Org. Lett. 2005, 7, 4185-4188.
Noriaki Itagaki, Mari Kimura, Tsutomu Sugahara, Yoshiharu Iwabuchi
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2004

Oxidative Rearrangement of Cyclic Tertiary Allylic Alcohols with IBX in DMSO
Org. Lett. 2004, 6, 4303-4306.
Masatoshi Shibuya, Shinichiro Ito, Machiyasu Takahashi, and Yoshiharu Iwabuchi
Total Synthesis and Absolute Stereochemistry of Pentenocin B, a Novel Interleukin-1β Converting Enzyme Inhibitor
J. Org. Chem. 2004, 69, 1744-1747.
Tsutomu Sugahara, Hayato Fukuda, and Yoshiharu Iwabuchi
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