{"id":1010,"date":"2022-05-16T14:37:40","date_gmt":"2022-05-16T05:37:40","guid":{"rendered":"http:\/\/www.pharm.tohoku.ac.jp\/research_center\/?page_id=1010"},"modified":"2022-06-07T09:10:43","modified_gmt":"2022-06-07T00:10:43","slug":"stress_saitou","status":"publish","type":"page","link":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/outview\/stress_saitou\/","title":{"rendered":"\u814e\u30fb\u4ee3\u8b1d\u30b9\u30c8\u30ec\u30b9\u30b0\u30eb\u30fc\u30d7\uff08\u658e\u85e4\u82b3\u90ce\u6559\u6388\uff09"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1010\" class=\"elementor elementor-1010\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7552a12 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7552a12\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container 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src=\"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/saitou.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/saitou.jpg 168w, https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/saitou-150x150.jpg 150w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><p id=\"caption-attachment-998\" class=\"wp-caption-text\">\u658e\u85e4 \u82b3\u90ce \u6559\u6388<\/p><\/div><p>\u30002\u578b\u7cd6\u5c3f\u75c5\u3067\u898b\u3089\u308c\u308b\u81b5\u03b2\u7d30\u80de\u306e\u969c\u5bb3\u3092\u6291\u5236\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u4fdd\u8b77\u3059\u308b\u65b0\u305f\u306a\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u30fb\u4e88\u9632\u6cd5\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u9ad8\u8840\u7cd6\u30fb\u9ad8\u8102\u80aa\u306b\u4f34\u3044\u809d\u81d3\u304b\u3089\u306e\u5206\u6ccc\u304c\u5897\u52a0\u3059\u308b\u201c\u30bb\u30ec\u30ce\u30d7\u30ed\u30c6\u30a4\u30f3\uff30\uff08SeP\uff09\u201d\u306b\u7740\u76ee\u3057\u3066\u3044\u307e\u3059\u3002SeP\u306f\u5fc5\u9808\u5fae\u91cf\u5143\u7d20\u30bb\u30ec\u30f3\uff08\u5143\u7d20\u8a18\u53f7Se\uff09\u3092\u542b\u3080\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u30bb\u30ec\u30f3\u3092\u7d30\u80de\u306b\u904b\u642c\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u3067\u5897\u52a0\u3057\u305fSeP\u306f\u3001\u81b5\u03b2\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3057\u7cd6\u4ee3\u8b1d\u3092\u60aa\u5316\u3059\u308b\u3053\u3068\u304b\u3089\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u91cd\u8981\u306a\u6cbb\u7642\u6a19\u7684\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u3068\u3057\u307e\u3057\u305f<sup>1)<\/sup>\u3002SeP\u306e\u7d30\u80de\u3078\u306e\u53d6\u308a\u8fbc\u307f\u3092\u6291\u5236\u3059\u308b\u4e2d\u548c\u6297\u4f53\u304c\u81b5\u03b2\u7d30\u80de\u4fdd\u8b77\u4f5c\u7528\u3092\u793a\u3059\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f<sup>1)<\/sup>\u3002\u307e\u305f\u3001SeP\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308blncRNA\u3000L-IST\u3092\u767a\u898b\u3057\u3001SeP\u3092\u4f4e\u4e0b\u3059\u308b\u5316\u5408\u7269\u3082\u8907\u6570\u898b\u3044\u3060\u3057\u3066\u3044\u307e\u3059<sup>2)<\/sup>\u3002\u73fe\u5728\u3001\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30e1\u30ac\u30d0\u30f3\u30af\u6a5f\u69cb\u306e\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u306b\u53c2\u753b\u3057\u3001SeP\u30ec\u30d9\u30eb\u3068\u75be\u60a3\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u6027\u306b\u3064\u3044\u3066\u8abf\u67fb\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u30e2\u30c7\u30eb\u52d5\u7269\u3084\u57f9\u990a\u7d30\u80de\u7cfb\u3092\u7528\u3044\u3001\u904e\u5270SeP\u306b\u3088\u308b\u81b5\u03b2\u7d30\u80de\u969c\u5bb3\u6a5f\u69cb\u3084\u809d\u81d3\u306eSeP\u767a\u73fe\u5236\u5fa1\u6a5f\u69cb\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u660e\u3089\u304b\u306b\u3057\u3001SeP\u3092\u6a19\u7684\u3068\u3057\u305f\u5275\u85ac\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<\/p><p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-1012\" src=\"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/stress_saitou_1-300x250.jpg\" alt=\"\" width=\"500\" height=\"416\" srcset=\"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/stress_saitou_1-300x250.jpg 300w, https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-content\/uploads\/2022\/05\/stress_saitou_1.jpg 685w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p><p>\u6587\u732e\uff1a<br \/>1) Nature Commun 8: 1658 (2017)<br \/>2) Nuc Acids Res 49: 6893-6907 (2021)<\/p><p>\u9023\u7d61\u5148\uff1a\u658e\u85e4\u82b3\u90ce\u3000<a href=\"mailto:yoshiro.saito.a8@tohoku.ac.jp\">yoshiro.saito.a8@tohoku.ac.jp<\/a><br \/><a href=\"http:\/\/www.pharm.tohoku.ac.jp\/~taisya\/index.html\" target=\"_blank\" rel=\"noopener\">http:\/\/www.pharm.tohoku.ac.jp\/~taisya\/index.html<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u81b5\u03b2\u7d30\u80de\u3092\u4fdd\u8b77\u3059\u308b2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u30fb\u4e88\u9632\u6cd5\u306e\u958b\u767a \u30002\u578b\u7cd6\u5c3f\u75c5\u3067\u898b\u3089\u308c\u308b\u81b5\u03b2\u7d30\u80de\u306e\u969c\u5bb3\u3092\u6291\u5236\u3057\u3001\u305d\u306e\u6a5f\u80fd\u3092\u4fdd\u8b77\u3059\u308b\u65b0\u305f\u306a\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u30fb\u4e88\u9632\u6cd5\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u9ad8\u8840\u7cd6\u30fb\u9ad8\u8102\u80aa\u306b\u4f34\u3044\u809d\u81d3\u304b\u3089\u306e\u5206\u6ccc\u304c\u5897\u52a0\u3059\u308b\u201c\u30bb\u30ec\u30ce [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":20,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"sns_share_botton_hide":"","vkExUnit_sns_title":"","_vk_print_noindex":"","sitemap_hide":"","vkExUnit_sitemap":"","_veu_custom_css":"","veu_display_promotion_alert":"","_exclude_from_list_pages":"","vkexunit_cta_each_option":"","vkExUnit_childPageIndex":"","vkExUnit_pageList_ancestor":"","vkExUnit_contact_enable":"","_lightning_design_setting":{"layout":"default"},"footnotes":""},"class_list":["post-1010","page","type-page","status-publish","hentry"],"veu_head_title_object":{"title":"","add_site_title":""},"_links":{"self":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/pages\/1010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/comments?post=1010"}],"version-history":[{"count":7,"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/pages\/1010\/revisions"}],"predecessor-version":[{"id":1213,"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/pages\/1010\/revisions\/1213"}],"up":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/pages\/20"}],"wp:attachment":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/research_center\/wp-json\/wp\/v2\/media?parent=1010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}