{"id":5438,"date":"2025-07-11T08:51:31","date_gmt":"2025-07-10T23:51:31","guid":{"rendered":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/?p=5438"},"modified":"2025-07-18T11:38:40","modified_gmt":"2025-07-18T02:38:40","slug":"hr-pks-ks%e3%83%89%e3%83%a1%e3%82%a4%e3%83%b3%e3%81%ae%e6%96%b0%e3%81%9f%e3%81%aa%e6%a9%9f%e8%83%bd%e3%81%ae%e7%99%ba%e8%a6%8b%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e8%ab%96%e6%96%87%e3%81%8cjacs","status":"publish","type":"post","link":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/hr-pks-ks%e3%83%89%e3%83%a1%e3%82%a4%e3%83%b3%e3%81%ae%e6%96%b0%e3%81%9f%e3%81%aa%e6%a9%9f%e8%83%bd%e3%81%ae%e7%99%ba%e8%a6%8b%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e8%ab%96%e6%96%87%e3%81%8cjacs\/","title":{"rendered":"HR-PKS-KS\u30c9\u30e1\u30a4\u30f3\u306e\u65b0\u305f\u306a\u6a5f\u80fd\u306e\u767a\u898b\u306b\u95a2\u3059\u308b\u8ad6\u6587\u304cJACS\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002"},"content":{"rendered":"\n<p>\u6771\u5317\u5927\u5b66\u3067\u7814\u7a76\u5ba4\u7acb\u3061\u4e0a\u3052\u6642\u306b\u914d\u5c5e\u3068\u306a\u3063\u305f\u7b2c1\u671f\u751f\u306e\u5ee3\u5ddd\u304f\u3093 (D3) 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href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c07060\">Ketosynthase Domain Catalyzes \u03b2-Lactonization in the Biosynthesis of the HMG-CoA Synthase Inhibitor Hymeglusin<\/a><\/p>\n\n\n\n<p>\u6771\u5317\u5927\u5b66 \u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9<\/p>\n\n\n\n<p><a href=\"https:\/\/www.tohoku.ac.jp\/japanese\/2025\/07\/press20250718-01-lactone.html\">\u03b2-\u30e9\u30af\u30c8\u30f3\u306e\u65b0\u305f\u306a\u751f\u5408\u6210\u6a5f\u69cb\u3092\u89e3\u660e \u65b0\u305f\u306a\u5275\u85ac\u30ea\u30fc\u30c9\u306e\u63a2\u7d22\u306b\u671f\u5f85<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6771\u5317\u5927\u5b66\u3067\u7814\u7a76\u5ba4\u7acb\u3061\u4e0a\u3052\u6642\u306b\u914d\u5c5e\u3068\u306a\u3063\u305f\u7b2c1\u671f\u751f\u306e\u5ee3\u5ddd\u304f\u3093 (D3) \u304c3\u5e74 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5434,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-5438","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogroll"],"_links":{"self":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/posts\/5438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/comments?post=5438"}],"version-history":[{"count":3,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/posts\/5438\/revisions"}],"predecessor-version":[{"id":5488,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/posts\/5438\/revisions\/5488"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/media\/5434"}],"wp:attachment":[{"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/media?parent=5438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/categories?post=5438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pharm.tohoku.ac.jp\/~shigen\/asai_lab\/wp-json\/wp\/v2\/tags?post=5438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}