Glycosides and glycoconjugates have biological activities. We synthesis glycosides andnglycoconjugates. Compared to other biopolymers such as DNA/RNA and proteins, carbohydrate structure is complex. It has branch structure and stereocontrol is required during glycosylation reaction. We are developing novel stereoselective glycosylation reaction and bioactive glycoside synthesis.
Antibody-drug conjugates are rapidly developing as next-therapeutic antibody medicine. We are developing novel ADC strategy based on organic chemistry and glycochemistry.