Research Interests:
Chemical modification on bioactive proteins/peptid
Structure/activity changes from chemically modified proteins/peptides
Analyses of chemically modified proteins/peptides as dosimeter/diagnostic/therapeutic markers
Analytical methodology for chemically modified proteins/peptides, chemical modificomics”
Development of future proteomics.
Education:
- 1992.11
- Ph. D. (Doctor of Pharmaceutical Science; analytical chemistry)
from Tohoku University, Sendai, Japan.
"Studies on the detection-oriented derivatizations for high-performance liquid chromatography";
- 1988.03
- Master of Pharmaceutical Science (analytical chemistry)
from Tohoku University, Sendai, Japan.
“Utilization of ferrocene as an electrophore to develop derivatization reagents for high-performance liquid chromatography /electrochemical detection”,
- 1986.03
- Bachelor of Pharmaceutical Science (analytical chemistry)
from Tohoku University, Sendai, Japan.
“Utilization of tetramethylbenzidine as a chromogenic substrate for horseradish peroxidase as a label in steroid enzyme immunoassays”.
Professional Career:
- 2007.09 - present
- Full Professor (tenure),
Department of Bio-analytical chemistry,
Graduate School of Pharmaceutical Sciences,
Tohoku University, Sendai, Japan.
- 2004.07 - 2007.08
- Research Assistant Professor,
Center for Cancer Pharmacology, Department of Pharmacology,
University of Pennsylvania, Philadelphia, PA, USA.
- 2000.04 - 2004.06
- Research Associate,
Center for Cancer Pharmacology, Department of Pharmacology,
University of Pennsylvania, Philadelphia, PA, USA.
- 1998.07 - 2000.03
- Lecturer
Department of Analytical Chemistry, School of Pharmaceutical Sciences,
University of Shizuoka, Shizuoka, Japan.
- 1996.12 - 1998.06
- Postdoctoral Fellow,
Center for Cancer Pharmacology, Department of Pharmacology,
University of Pennsylvania, Philadelphia, PA, USA.
- 1996.03 - 1996.11
- Postdoctoral Fellow,
Bioanalytical Resource, Department of Pharmacology,
Vanderbilt University, Nashville, TN, USA.
- 1995.05 - 1996.02
- Visiting Research Fellow (supported by Ministry of Education, Japan),
Department of Pharmacology, Vanderbilt University, Nashville, TN, USA.
- 1995.04 - 1996.02
- Instructor,
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences,
Tohoku University, Sendai, Japan.
- 1994.04 - 1995.03
- Instructor,
Department of Molecular Toxicology, Faculty of Pharmaceutical Sciences,
Tohoku University, Sendai, Japan.
- 1992.01 - 1994.03
- Research Associate,
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences,
Tohoku University, Sendai, Japan.
- 1988.04 - 1991.12
- Research Associate,
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences,
Kanazawa University, Kanazawa, Japan.
Organizations:
Japan Society of Amino Acid Analysis (2011-),
The Pharmaceutical Society of Japan (1986-),
The Japan Society for Analytical Chemistry (1988-),
American Society for Mass Spectrometry (1995-),
Japanese Society of Mass Spectrometry (1998-),
The Society for Chromatographic Sciences, Japan (1998-),
The Society of Synthetic Organic Chemistry Japan (1998-),
American Chemical Society (2001-),
California Society for Separation Sciences (1998-2000),
American Association for Cancer Research (2002-2007).
Other
Phermacist License (1986 ~ )