Full Publications

Journal Publications

  1. Yoshikai, N. Exploring New Reactions and Syntheses of Trivalent Iodine Compounds. J. Synth. Org. Chem. Jpn. 2022, 80, 1011-1018.

  1. Kikuchi, J.; Maesaki, K.; Sasaki, S.; Wang, W.; Ito, S.; Yoshikai, N. Stereoselective Synthesis of β-Alkoxy-β-amido Vinylbenziodoxoles via Iodo(III)etherification of Ynamides. Org. Lett. 2022, 24, 6914-6918.

  1. Tsukiji, K.; Sekiguchi, Y.; Kanemoto, K.; Yoshikai, N. Diastereoselective Conversion of Cyclopropanols to Cyclopentane-1,3-diols via Aldol Dimerization of Zinc Homoenolates. Chem. Lett. 2022, DOI: 10.1246/cl.220311.

  1. Kikuchi, J.; Yoshikai, N. Cobalt Selectively Annulates. Nat. Synth. 2022, DOI: 10.1038/s44160-022-00126-0 (News & Views).

  1. Wang, C.-S.; Yu, Y.; Sunada, Y.; Wang, C.; Yoshikai, N. Cobalt-Catalyzed Carbo- and Hydrocyanation of Alkynes via C-CN Bond Activation. ACS Catal. 2022, 12, 4054-4066.

  1. Sekiguchi, Y.; Yoshikai, N. Zinc-Mediated Hydroxyallylation of Aldehydes with Cyclopropanols: Direct Access to Vicinal anti-sec,tert-Diols via Enolized Homoenolate. Org. Lett. 2022, 24, 960-965 (Preprint: Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI: 10.26434/chemrxiv-2021-swc95)

  1. Wang, C.-S.; Tan, P. S. L.; Ding, W.; Ito, S.; Yoshikai, N. Regio- and Stereoselective Synthesis of Enol Carboxylate, Phosphate, and Sulfonate Esters via Iodo(III)functionalization of Alkynes. Org. Lett. 2022, 24, 430-434.

  1. Chai, J.; Ding, W.; Wang, C.; Ito, S.; Wu, J.; Yoshikai, N. Ritter-Type Iodo(III)amidation of Unactivated Alkynes for the Stereoselective Synthesis of Multisubstituted Enamides. Chem. Sci. 2021, 12, 15128-15133 (Preprint: Chai, J.; Ding, W.; Ito, S.; Wu, J.; Yoshikai, N. ChemRxiv 2021, DOI: 10.33774/chemrxiv-2021-c2ftp).

  1. Sekiguchi, Y.; Yoshikai, N. Zinc-Catalyzed β-Functionalization of Cyclopropanols via Enolized Homoenolate. J. Am. Chem. Soc. 2021, 143, 18400-18405 (Preprint: Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI: 10.33774/chemrxiv-2021-4jlsp).

  1. Sekiguchi, Y.; Lee, Y. Y.; Yoshikai, N. Nickel-Catalyzed Ring-Opening Allylation of Cyclopropanols via Homoenolate. Org. Lett. 2021, 23, 5993-5997.

  1. Sekiguchi, Y.; Yoshikai, N. Enantioselective Conjugate Addition of Catalytically Generated Zinc Homoenolate. J. Am. Chem. Soc. 2021, 143, 4775-4781 (Preprint: Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI: 10.26434/chemrxiv.13607438.v1).

  1. Wang, C.-S.; Sun, Q.; Garcia, F.; Wang, C.; Yoshikai, N. Robust Cobalt Catalyst for Nitrile/Alkyne [2+2+2] Cycloaddition: Synthesis of Polyarylpyridines and Their Mechanochemical Cyclodehydrogenation to Nitrogen-Containing Polyaromatics. Angew. Chem. Int. Ed. 2021, published online (Preprint: Wang, C.-S.; Sun, Q.; Garcia, F.; Wang, C.; Yoshikai, N. ChemRxiv 2021, DOI: 10.26434/chemrxiv.13465697.v1)

  1. Laskar, R. A.; Ding, W.; Yoshikai, N. Iodo(III)-Meyer-Schuster Rearrangement of Propargylic Alcohols Promoted by Benziodoxole Triflate. Org. Lett. 2021, 23, 1113-1117.

  1. Sekiguchi, Y.; Yoshikai, N. Metal-Catalyzed Transformations of Cyclopropanols via Homoenolates. Bull. Chem. Soc. Jpn. 2021, 1, 265-280.

  1. Xu, W.; Wu, M.; Yoshikai, N. Iron-Catalyzed Remote C-H Alkylation of 8-Amidoquinolines with Cycloalkanes. Synthesis 2020, published online.

  1. Chai, J.; Ding, W.; Wu, J.; Yoshikai, N. Fluorobenziodoxole-BF3 Reagent for Iodo(III)etherification of Alkynes in Ethereal Solvent. Chem. Asian J. 2020, 15, 2166-2169.

  1. Ding, W.; Wang, C.; Tan, J. R.; Ho, C. C.; León, F.; García, F.; Yoshikai, N. Site-selective aromatic C-H λ3-iodanation with cyclic iodine(III) electrophile in solution and solid phases. Chem. Sci. 2020, 11, 7356-7361.

  1. Yang, J.; Mori, Y.; Yamanaka, M.; Yoshikai, N. Cobalt‐Catalyzed Intramolecular Hydroacylation Involving Cyclopropane Cleavage. Chem. Eur. J. 2020, 26, 8302-8307.

  1. Ding, W.; Chai, J.; Wang, C.; Wu, J.; Yoshikai, N. Stereoselective Access to Highly Substituted Vinyl Ethers via trans-Difunctionalization of Alkynes with Alcohols and Iodine(III) Electrophile. J. Am. Chem. Soc. 2020, 142, 8619-8624 (Preprint: Ding, W.; Chai, J.; Wu, J.; Yoshikai, N. ChemRxiv 2020, DOI: 10.26434/chemrxiv.11770092.v1.)

  1. Wang, C.-S.; Di Monaco, S.; Thai, A. N.; Rahman, M. S.; Pang, B. P.; Wang, C.; Yoshikai, N. Cobalt/Lewis Acid Catalysis for Hydrocarbofunctionalization of Alkynes via Cooperative C–H Activation. J. Am. Chem. Soc. 2020, 142, 12878-12889 (Preprint: Wang, C.-S.; Di Monaco, S.; Thai, A. N.; Wang, C.; Yoshikai, N. ChemRxiv 2020, DOI: 10.26434/chemrxiv.11760519.v1.)

  1. Rahman, M. S.; Yoshikai, N. Synthesis of Triphenylene-Fused Phosphole Oxides via C-H Functionalizations. Beilstein J. Org. Chem. 2020, 16, 524-529.

  1. Laskar, R. A.; Yoshikai, N. Cobalt-Catalyzed, N–H Imine-Directed Arene C–H Benzylation with Benzyl Phosphates. J. Org. Chem. 2019, 84, 13172-13178.

  1. Ding, W.; Ho, Y. K. T.; Okuda, Y.; Wijaya, K. C.; Tan, Z. H.; Yoshikai, N. Cobalt-Catalyzed Hydroacylative Dimerization of Allenes Leading to Skipped Dienes. Org. Lett. 2019, 21, 6173-6178.

  1. Sun, Q.; Yoshikai, N. Cobalt-Catalyzed Tandem Radical Cyclization/C–C Coupling Initiated by Directed C–H Activation. Org. Lett. 2019, 21, 5238-5242.

  1. Rahman, M. S.; Yoshikai, N. Synthesis and Properties of Phospha[5]helicenes Bearing Inner-Rim Phosphorus Center. Org. Lett. 2019, 21, 3232-3236.

  1. Yang, J.; Sekiguchi, Y.; Yoshikai, N. Cobalt-Catalyzed Enantioselective and Chemodivergent Addition of Cyclopropanols to Oxabicyclic Alkenes. ACS Catal. 2019, 9, 5638-5644.

  1. Wu, J.; Deng, X.; Yoshikai, N. Stereocontrolled Synthesis of Halovinylbenziodoxoles via Hydro- and Iodochlorination of Ethynylbenziodoxoles. Chem. Eur. J. 2019, 25, 7839-7842.

  1. Xu, W.; Yoshikai, N. Iron‐Catalyzed ortho C−H Arylation and Methylation of Pivalophenone N−H Imines. ChemSusChem 2019, 12, 3049-3053.

  1. Yan, J.; Rahman, M. S.; Yoshikai, N. Pd‐Catalyzed Annulation of 1‐Halo‐8‐arylnaphthalenes and Alkynes Leading to Heptagon‐Embedded Aromatic Systems. Chem. Eur. J. 2019, 25, 9395-9399.

  1. Yang, J.; Sun, Q.; Yoshikai, N. Cobalt-Catalyzed Regio- and Diastereoselective Formal [3+2] Cycloaddition between Cyclopropanols and Allenes. ACS Catal. 2019, 9, 1973-1978.

  1. Ding, W.; Yoshikai, N. Cobalt-Catalyzed Intermolecular [2+2] Cycloaddition between Alkynes and Allenes. Angew. Chem. Int. Ed. 2019, 58, 2500-2504.

  1. Ding, W.; Ho, C. C.; Yoshikai, N. Photosensitized, Energy-Transfer-Mediated Cyclization of 2-(1-Arylvinyl)benzaldehydes to Anthracen-9-(10H)-ones. Org. Lett. 2019, 21, 1202-1206.

  1. Yoshikai, N. Recent Advances in Enantioselective C-C Bond Formation via Organocobalt Species. Synthesis 2019, 51, 135-145.

  1. Yang, J.; Shen, Y.; Lim, Y. J.; Yoshikai, N. Divergent ring-opening coupling between cyclopropanols and alkynes under cobalt catalysis. Chem. Sci. 2018, 9, 6928-6934.

  1. Sun, Q.; Yoshikai, N. Cobalt-catalyzed directed ortho-methylation of arenes with methyl tosylate. Org. Chem. Front. 2018, 7, 2214-2218.

  1. Wu, C.; Yoshikai, N. Cobalt-Catalyzed Intramolecular Reactions between a Vinylcyclopropane and an Alkyne: Switchable [5+2] Cycloaddition and Homo-Ene Pathways. Angew. Chem. Int. Ed. 2018, 57, 6558-6562.

  1. Xu, W.; Pek, J. H.; Yoshikai, N. Iron-Catalyzed Directed C–H Silylation of Pivalophenone N–H Imines. Asian J. Org. Chem. 2018, 14, 1351-1354.

  1. Xu, W.; Yoshikai, N. Cobalt-Catalyzed Directed C–H Alkenylation of Pivalophenone N–H Imine with Alkenyl Phosphates. Beilstein J. Org. Chem. 2018, 14, 709-715.

  1. Sun, Q.; Yoshikai, N. Cobalt-Catalyzed C(sp2)–H/C(sp3)–H Coupling via Directed C– H Activation and 1,5-Hydrogen Atom Transfer. Org. Chem. Front. 2018, 5, 582-585.

  1. Tan, W. W.; Wu, B.; Wei, Y.; Yoshikai, N. Copper and Secondary Amine-Catalyzed Pyridine Synthesis from O-Acetyl Oximes and α,β-Unsaturated Aldehydes. Org. Synth. 2018, 95, 1-14.

  1. Xu, W.; Yoshikai, N. Cobalt-Catalyzed, N–H Imine-Directed Hydroarylation of Styrenes. Org. Lett. 2018, 20, 1392-1395.

  1. Lee, P.-S.; Xu, W.; Yoshikai, N. Directed C–H Alkenylation of Aryl Imines with Alkenyl Phosphates Promoted by a Cobalt–N-Heterocyclic Carbene Catalyst. Adv. Synth. Catal. 2017, 359, 4340-4347 (Very Important Paper).

  1. Yan, J.; Yoshikai, N. Phenanthrene Synthesis via Chromium-Catalyzed Annulation of 2-Biaryl Grignard Reagents and Alkynes. Org. Lett. 2017, 19, 6630-6633.

  1. Wu, B.; Wu, J.; Yoshikai, N. Benziodoxole Triflate as a Versatile Reagent for Iodo(III)cyclization of Alkynes. Chem. Asian J. 2017, 12, 3123-3127.

  1. Yoshikai, N. Iron-Catalyzed C–C Bond Formation via Chelation-Assisted C–H Activation. Isr. J. Chem. 2017, 57, 1117-1130.

  1. Yan, J.; Yoshikai, N. Chromium-Catalyzed Migratory Arylmagnesiation of Unactivated Alkynes. Org. Chem. Front. 2017, 4, 1972-1975.

  1. Xu, W.; Yoshikai, N. Pivalophenone Imine as a Benzonitrile Surrogate for Directed C–H Bond Functionalization. Chem. Sci. 2017, 8, 5299-5304.

  1. Yoshikai, N.; Santra, M.; Wu, B. Synthesis of Donor-Acceptor-Type Benzo[b]phosphole and Naphtho[2,3-b]phosphole Oxides and Their Solvatochromic Properties. Organometallics 2017, 20, 1392-1395.

  1. Tan, W. W.; Ong, Y. J.; Yoshikai, N. Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines. Angew. Chem. Int. Ed. 2017, 56, 8240-8244.

  1. Wu, B.; Melvina; Wu, X.; Yeow, E. K. L.; Yoshikai, N. Versatile Telluracyclc Synthesis via the Sequential Electrophilic Telluration of C(sp2)–Zn and C(sp2)–H Bonds. Chem. Sci. 2017, 8, 4527-4532.

  1. Yang, J.; Rérat, A.; Lim, Y. J.; Gosmini, C.; Yoshikai, N. Cobalt-Catalyzed Enantio- and Diastereoselective Hydroacylation of Trisubstituted Alkenes. Angew. Chem. Int. Ed. 2017, 56, 2449-2453.

  1. Wu, J.; Xu, K.; Hirao, H.; Yoshikai, N. Pd-Catalyzed, Ligand-Enabled Stereoselective 1,2-Iodine(III) Shift/1,1-Carboxyalkynylation of Alkynylbenziodoxoles. Chem. Eur. J. 2017, 23, 1521-1525.

  1. Xu, W.; Yoshikai, N. N–H Imine as a Powerful Directing Group for Cobalt-Catalyzed Olefin Hydroarylation. Angew. Chem. Int. Ed. 2016, 55, 12731-12735.

  1. Xu, W.; Pek, J. H.; Yoshikai, N. Cobalt-Catalyzed, Imine-Directed Olefin Hydroarylation under Grignard-Free Conditions. Adv. Synth. Catal. 2016, 358, 2564-2568.

  1. Wu, J.; Deng, X.; Hirao, H.; Yoshikai, N. Pd-Catalyzed Conversion of Alkynyl-λ3-iodanes to Alkenyl-λ3-iodanes via Stereoselective 1,2-Iodine(III) Shift/1,1- Hydrocarboxylation. J. Am. Chem. Soc. 2016, 138, 9105-9108.

  1. Tan, W. W.; Yoshikai, N. Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes. J. Org. Chem. 2016, 81, 5566-5573.

  1. Yan, J.; Yoshikai, N. Cobalt-Catalyzed Arylative Cyclization of Acetylenic Esters and Ketones with Arylzinc Reagents through 1,4-Cobalt Migration. ACS Catal. 2016, 6, 3738-3742.

  1. Wu, B.; Yoshikai, N. Recent Developments in Synthetic Methods for Benzo[b]heteroles. Org. Biomol. Chem. 2016, 14, 5402-5416.

  1. Yang, J.; Yoshikai, N. Cobalt-Catalyzed Annylation of Salicylaldehydes and Alkynes to Form Chromones and 4-Chromanones. Angew. Chem. Int. Ed. 2016, 55, 2870-2874.

  1. Wu, J.; Yoshikai, N. Cobalt-Catalyzed Alkenylzincation of Unfunctionalized Alkynes. Angew. Chem. Int. Ed. 2016, 55, 336-340.

  1. Wu, B.; Chopra, R.; Yoshikai, N. One-Pot Benzo[b]phosphole Synthesis through Sequential Alkyne Arylmagnesiation, Electrophilic Trapping, and Intramolecular Phospha-Friedel–Crafts Cyclization. Org. Lett. 2015, 17, 5666-5669.

  1. Wu, J.; Yoshikai, N. Modular Synthesis of Multisubstituted Furans through Palladium-Catalyzed Three-Component Condensation of Alkynylbenziodoxoles, Carboxylic Acids, and Imines. Angew. Chem. Int. Ed. 2015, 54, 11107-11111.

  1. Xu, W.; Paira, R.; Yoshikai, N. Ortho-C–H Benzylation of Aryl Imines with Benzyl Phosphates under Cobalt–Pyphos Catalysis. Org. Lett. 2015, 17, 4192-4195.

  1. Tan, W. W.; Yoshikai, N. Copper-Catalyzed Condensation of Imines and α-Diazo-β-dicarbonyl Compounds: Modular and Regiocontrolled Synthesis of Multisubstituted Pyrroles. Chem. Sci. 2015, 6, 6448-6455.

  1. Wu, B.; Yoshikai, N. Conversion of 2-Iodobiaryls into 2,2-Diiodobiaryls via Oxidation- Iodination Sequences: A Versatile Route to Ladder-Type Heterofluorenes. Angew. Chem. Int. Ed. 2015, 54, 8736-8739.

  1. Yang, J.; Seto, Y. W.; Yoshikai, N. Cobalt-Catalyzed Intermolecular Hydroacylation of Olefins through Chelation-Assisted Imidoyl C–H Activation. ACS Catal. 2015, 5, 3054-3057.

  1. Yoshikai, N. Cp*CoIII-Catalyzed C–H Activation of (Hetero)arenes: Expanding the Scope of Base-Metal-Catalyzed C–H Functionalization. ChemCatChem 2015, 7, 732-734.(one of most accessed articles in Feb 2015)

  1. Wong, M. Y.; Yamakawa, T.; Yoshikai, N. Iron-Catalyzed Directed C2-Alkylation and Alkenylation of Indole with Vinylarenes and Alkynes. Org. Lett. 2015, 17, 442-445.

  1. Lee, P.-S.; Yoshikai, N. Cobalt-Catalyzed Enantioselective Directed C–H Alkylation of Indoles with Styrenes. Org. Lett. 2015, 17, 22-25.

  1. Yamakawa, T.; Seto, Y. W.; Yoshikai, N. Cobalt-Catalyzed Directed Alkylation of Olefinic C–H Bond with Primary and Secondary Alkyl Chlorides. Synlett 2015, 26, 340-344.

  1. Xu, W.; Yoshikai, N. Highly Linear-Selective Cobalt-Catalyzed Addition of Aryl Imines to Styrenes: Reversing Intrinsic Regioselectivity by Ligand Elaboration. Angew. Chem. Int. Ed. 2014, 53, 14166-14170.

  1. Yang, J.; Yoshikai, N. Cobalt-Catalyzed Enantioselective Intramolecular Hydroacylation of Ketones and Olefins. J. Am. Chem. Soc. 2014, 136, 16748-16751. [one of most accessed articles in Nov 2014]

  1. Yoshikai, N. Cobalt-Catalyzed C–C Bond-Forming Reactions via Chelation-Assisted C–H Activation. J. Synth. Org. Chem. Jpn. 2014, 72, 1198-1206.

  1. Tan, W. W.; Hou, X.; Yoshikai, N. Pd(II)/Bu4NBr/DMSO Catalytic System for Practical Synthesis of Indoles and Pyrroles from Imines through Aerobic Dehydrogenative Cyclization. Synthesis 2014, 46, 2727-2733.

  1. Lu, B.; Wu, J.; Yoshikai, N. Palladium-Catalyzed Condensation of N-Aryl Imines and Alkynylbenziodoxolones To Form Multisubstituted Furans. J. Am. Chem. Soc. 2014, 136, 11598-11601.

  1. Yoshikai, N. Development of Cobalt-Catalyzed C–H Bond Functionalization Reactions. Bull. Chem. Soc. Jpn. 2014, 87, 843-857.

  1. Karthikeyan, J.; Yoshikai, N. Rhodium(III)-Catalyzed Directed peri-C–H Alkenylation of Anthracene Derivatives. Org. Lett. 2014, 16, 4224-4227.

  1. Gao, K.; Yamakawa, T.; Yoshikai, N. Cobalt-Catalyzed Chelation-Assisted Alkylation of Arenes with Primary and Secondary Alkyl Halides. Synthesis 2014, 46, 2024-2039 (Feature Article).

  1. Wu, B.; Santra, M.; Yoshikai, N. A Highly Modular One-Pot Multicomponent Approach to Functionalized Benzo[b]phosphole Derivative. Angew. Chem. Int. Ed. 2014, 53, 7543-7546. [Highlighted in Synfacts 2014, 10, 928]

  1. Tan, B.-H.; Yoshikai, N. Cobalt-Catalyzed Addition of Arylzinc Reagents to Norbornene Derivatives through 1,4-Cobalt Migration. Org. Lett. 2014, 16, 3392-3395.

  1. Asako, S.; Norinder, J.; Ilies, L.; Yoshikai, N.; Nakamura, E. ortho-Allylation of 1- Arylpyrazole with Allyl Phenyl Ether via Iron-Catalyzed C–H Bond Activation under Mild Conditions. Adv. Synth. Catal. 2014, 356, 1481-1485.

  1. Gao, K.; Paira, R.; Yoshikai, N. Cobalt-Catalyzed Ortho-C–H Alkylation of 2-Arylpyridines via Ring-Opening of Aziridines. Adv. Synth. Catal. 2014, 356, 1486-1490.

  1. Yoshikai, N.; Gao, K. Cobalt-Catalyzed Directed Alkylation of Arenes with Primary and Secondary Alkyl Halides. Pure Appl. Chem. 2014, 86, 419-424.

  1. Yamakawa, T.; Yoshikai, N. Alkene Isomerization–Hydroarylation Tandem Catalysis: Indole C2-Alkylation with Aryl-Substituted Alkenes Leading to 1,1-Diarylalkanes. Chem. Asian J. 2014, 9, 1242-1246.

  1. Gao, K.; Yoshikai, N. Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization. Acc. Chem. Res. 2014, 47, 1208-1219.

  1. Rijs, N. J.; Yoshikai, N.; Nakamura, E.; O’Hair, R. A. J. Unraveling Organocuprate Complexity: Fundamental Insights into Intrinsic Group Transfer Selectivity in Alkylation Reactions. J. Org. Chem. 2014, 79, 1320-1334.

  1. Harano, K.; Takenaga, S.; Okada, S.; Niimi, Y.; Yoshikai, N.; Isobe, H.; Suenaga, K.; Kataura, H.; Koshino, M.; Nakamura, E. Conformational Analysis of Single Perfluoroalkyl Chains by Single-Molecule Real-Time Transmission Electron Microscopic Imaging. J. Am. Chem. Soc. 2014, 136, 466-473.

  1. Wu, B.; Yoshikai, N. Versatile Synthesis of Benzothiophenes and Benzoselenophenes by Rapid Assembly of Arylzinc Reagents, Alkynes, and Elemental Chalcogens. Angew. Chem. Int. Ed. 2013, 52, 10496-10499.

  1. Deb, I.; Yoshikai, N. Phenanthridine Synthesis through Iron-Catalyzed Intramolecular N-Arylation of O-acetyl Oxime. Org. Lett. 2013, 15, 4254-4257.

  1. Ding, Z.; Yoshikai, N. Cobalt-Catalyzed Intramolecular Olefin Hydroarylation Leading to Dihydropyrroloindoles and Tetrahydropyridoindoles. Angew. Chem. Int. Ed. 2013, 52, 8574-8578.

  1. Dong, J.; Lee, P.-S.; Yoshikai, N. Cobalt-Catalyzed Branched-Selective Addition of Aromatic Ketimines to Styrenes under Room Temperature Conditions. Chem. Lett. 2013, 42, 1140-1142.

  1. Gao, K.; Yoshikai, N. Cobalt-Catalyzed Ortho Alkylation of Aromatic Imines with Primary and Secondary Alkyl Halides. J. Am. Chem. Soc. 2013, 135, 9279-9282.

  1. Chen, Z.; Lu, B.; Ding, Z.; Gao, K.; Yoshikai, N. α-Palladation of Imines as Entry to Dehydrogenative Heck Reaction: Aerobic Oxidative Cyclization of N-Allylimines to Pyrroles. Org. Lett. 2013, 15, 1966-1969.

  1. Yoshikai, N.; Wei, Y. Synthesis of Pyrroles, Indoles, and Carbazoles through Transition Metal-Catalyzed C–H Functionalization. Asian J. Org. Chem. 2013, 2, 466-478.

  1. Yamakawa, T.; Yoshikai, N. Cobalt-Catalyzed ortho-Alkenylation of Aromatic Aldimines via Chelation-Assisted C–H Bond Activation. Tetrahedron 2013, 69, 4459-4465.

  1. Wei, Y.; Yoshikai, N. Modular Pyridine Synthesis from Oximes and Enals through Synergistic Copper/Iminium Catalysis. J. Am. Chem. Soc. 2013, 135, 3756-3759.

  1. Yamakawa, T.; Yoshikai, N. Annulation of α,β-Unsaturated Imines and Alkynes via Cobalt-Catalyzed Olefinic C–H Activation. Org. Lett. 2013, 15, 196-199.

  1. Lee, P.-S.; Yoshikai, N. Aldimine-Directed Branched-Selective Hydroarylation of Styrenes. Angew. Chem. Int. Ed. 2013, 52, 1240-1244.

  1. Hajra, A.; Wei, Y.; Yoshikai, N. Palladium-Catalyzed Aerobic Dehydrogenative Aromatization of Cyclohexanone Imines to Arylamines. Org. Lett. 2012, 14, 5488-5491.

  1. Ilies, L.; Matsumoto, A.; Kobayashi, M.; Yoshikai, N.; Nakamura, E. Synthesis of Polysubstituted Naphthalenes by Iron-Catalyzed [2+2+2] Annulation of Grignard Reagents with Alkynes. Synlett 2012, 2381-2384.

  1. Tan, B.-H.; Dong, J.; Yoshikai, N. Cobalt-Catalyzed Addition of Arylzinc Reagents to Alkynes to Form ortho-Alkenylarylzinc Species through 1,4-Cobalt Migration. Angew. Chem. Int. Ed. 2012, 51, 9610-9614.

  1. Ding, Z.; Yoshikai, N. C2-Alkylation of N-Pyrimidylindole with Vinylsilanes via Cobalt-Catalyzed C-H Bond Activation. Beilstein J. Org. Chem. 2012, 8, 1536-1542.

  1. Gao, K.; Lee, P.-S.; Long, C.; Yoshikai, N. Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides. Org. Lett. 2012, 14, 4234-4237.

  1. Nakamura, Y.; Yoshikai, N.; Ilies, L.; Nakamura, E. Nickel-Catalyzed Monosubsitution of Polyfluoroarenes with Organozinc Reagents Using Alkoxydiphosphine Ligand. Org. Lett. 2012, 14, 3316-3319.

  1. Adak, L.; Yoshikai, N. Iron-Catalyzed Annulation Reaction of Arylindium Reagents and Alkynes to Produce Substituted Naphthalenes. Tetrahedron 2012, 68, 5167-5171.

  1. Wei, Y.; Deb, I.; Yoshikai, N. Palladium-Catalyzed Aerobic Oxidative Cyclization of N-Aryl Imines: Indole Synthesis from Anilines and Ketones. J. Am. Chem. Soc. 2012, 134, 9098-9101.

  1. Ding, Z.; Yoshikai, N. Mild and Efficient C2-Alkenylation of Indoles with Alkynes Catalyzed by a Cobalt Complex. Angew. Chem. Int. Ed. 2012, 51, 4698-4701.

  1. Gao, K.; Yoshikai, N. Cobalt-Catalyzed Arylation of Aldimines via Directed C–H Bond Functionalization: Addition of 2-Arylpyridines and Self-Coupling of Aromatic Aldimines. Chem. Commun. 2012, 48, 4305-4307.

  1. Yoshikai, N.; Nakamura, E. Mechanisms of Nucleophilic Organocopper(I) Reactions. Chem. Rev. 2012, 112, 2339-2372.

  1. Ilies, L.; Kobayashi, M.; Matsumoto, A.; Yoshikai, N.; Nakamura, E. Iron-Catalyzed Nitrogen-Directed Coupling of Arene and Aryl Bromides Mediated by Metallic Magnesium. Adv. Synth. Catal. 2012, 354, 593-596.

  1. Rijs, N.; Yoshikai, N.; Nakamura, E.; O’Hair, R. A. J. Gas-Phase Reactivity of Group 11 Dimethylmetallates with Allyl Iodide. J. Am. Chem. Soc. 2012, 134, 2569-2580.

  1. Yoshikai, N.; Asako, S.; Yamakawa, T.; Ilies, L.; Nakamura, E. Iron-Catalyzed C–H Bond Activation for the ortho-Arylation of Aryl Pyridines and Imines with Grignard Reagents. Chem. Asian. J. 2011, 6, 3059-3065.

  1. Lee, P.-S.; Fujita, T.; Yoshikai, N. Cobalt-Catalyzed, Room-Temperature Addition of Aromatic Imines to Alkynes via Directed C–H Bond Activation. J. Am. Chem. Soc. 2011, 133, 17283-17295.

  1. Wei, Y.; Yoshikai, N. Oxidative Cyclization of 2-Arylphenols to Dibenzofurans under Pd(II)/Peroxybenzoate Catalysis. Org. Lett. 2011, 13, 5504-5507.

  1. Adak, L.; Yoshikai, N. Cobalt-Catalyzed Preparation of Arylindium Reagents from Aryl and Heteroaryl Bromides. J. Org. Chem. 2011, 76, 7563-7568.

  1. Gao, K.; Yoshikai, N. Cobalt–Phenanthroline Catalysts for the ortho Alkylation of Aromatic Imines under Mild Conditions. Angew. Chem. Int. Ed. 2011, 50, 6888-6892.

  1. Ding, Z.; Yoshikai, N. Cobalt-Catalyzed Alkenylation of Thiazoles with Alkynes via C–H Bond Functionalization. Synthesis 2011, 2561-2566.

  1. Chen, Q.; Ilies, L.; Yoshikai, N.; Nakamura, E. Cobalt-Catalyzed Coupling of Alkyl Grignard Reagent with Benzamide and 2-Phenylpyridine Derivatives through Directed C–H Bond Activation under Air. Org. Lett. 2011, 13, 3232-3234.

  1. Yoshikai, N. Cobalt-Catalyzed, Chelation-Assisted C-H Bond Functionalization. Synlett 2011, 1047-1051. * Invited highlight article

  1. Jin, M.-Y.; Yoshikai, N. Cobalt–Xantphos Catalyzed, LiCl-Mediated Preparation of Arylzinc Reagents from Aryl Iodides, Bromides, and Chlorides. J. Org. Chem. 2011, 76, 1972-1978 (Featured Article).

  1. Gao, K.; Yoshikai, N. Regioselectivity-Switchable Hydroarylation of Styrenes. J. Am. Chem. Soc. 2011, 133, 400-402.

  1. Adak, L.; Chan, W. C.; Yoshikai, N. Nickel-Catalyzed, Directing Group-Assisted [2 + 2 + 2] Cycloaddition of Imine and Alkynes. Chem. Asian. J. 2011, 6, 359-362.

  1. Ding, Z.; Yoshikai, N. Cobalt-Catalyzed Addition of Azoles to Alkynes. Org. Lett. 2010, 12, 4180-4183.

  1. Gao, K.; Lee, P.-S.; Fujita, T.; Yoshikai, N. Cobalt-Catalyzed Hydroarylation of Alkynes through Chelation-Assisted C-H Bond Activation. J. Am. Chem. Soc. 2010, 132, 12249-12251.

  1. Nakamura, E.; Yoshikai, N. Low-Valent Iron-Catalyzed C–C Bond Formation— Addition, Substitution, and C–H Bond Activation. J. Org. Chem. 2010, 75, 6061-6067.

  1. Ilies, L.; Okabe, J.; Yoshikai, N.; Nakamura, E. Iron-Catalyzed, Directed Oxidative Arylation of Olefins with Organozinc and Grignard Reagents. Org. Lett. 2010, 12, 2838-2840.

  1. Gärtner, T.; Yoshikai, N.; Neumeier, M.; Nakamura, E.; Gschwind, R. M. Ligand Exchange Reactions in Cu(III) Complexes: Mechanistic Insights by Combined NMR and DFT Studies. Chem. Commun. 2010, 46, 4625-4626.

  1. Yoshikai, N.; Mieczkowski, A.; Matsumoto, A.; Ilies, L.; Nakamura, E. Iron-Catalyzed C-C Bond Formation at α-Position of Aliphatic Amines via C-H Bond Activation through 1,5-Hydrogen Transfer. J. Am. Chem. Soc. 2010, 132, 5568-5569.

  1. Yoshikai, N.; Matsumoto, A.; Norinder, J.; Nakamura, E. Iron-Catalyzed Direct Arylation of Aryl Pyridines and Imines Using Oxygen as an Oxidant. Synlett 2010, 313-316.

  1. Yoshikai, N.; Matsuda, H.; Nakamura, E. Hydroxyphosphine Ligand for Nickel-Catalyzed Cross-Coupling through Nickel/Magnesium Bimetallic Cooperation. J. Am. Chem. Soc. 2009, 131, 9590-9599.

  1. Yoshikai, N.; Miura, K.; Nakamura, E. Enantioselective Copper-Catalyzed Allylic Substitution with Aminohydroxyphosphine Ligand. Adv. Synth. Catal. 2009, 351, 1014-1018.

  1. Yoshikai, N.; Matsumoto, A.; Norinder, J.; Nakamura, E. Iron-Catalyzed Chemoselective ortho Arylation of Aryl Imines by Directed C-H Bond Activation. Angew. Chem. Int. Ed. 2009, 48, 2925-2928.

  1. Yoshikai, N.; Zhang, S.-L.; Yamagata, K.-i.; Tsuji, H.; Nakamura, E. Mechanistic Study of the Manganese-Catalyzed [2 + 2 + 2] Annulation of 1,3-Dicarbonyl Compounds and Terminal Alkynes. J. Am. Chem. Soc. 2009, 131, 4099-4109.

  1. Yoshikai, N.; Matsuda, H.; Nakamura, E. Ligand Exchange as the First Irreversible Step in the Nickel-Catalyzed Cross-Coupling Reaction of Grignard Reagents. J. Am. Chem. Soc. 2008, 130, 15258-15259.

  1. Yoshikai, N.; Zhang, S.-L.; Nakamura, E. Origin of the Regio- and Stereoselectivity of Allylic Substitution of Organocopper Reagents. J. Am. Chem. Soc. 2008, 130, 12862-12863.

  1. Norinder, J.; Matsumoto, A.; Yoshikai, N.; Nakamura, E. Iron-Catalyzed Direct Arylation through Directed C-H Bond Activation. J. Am. Chem. Soc. 2008, 130, 5858-5859.

  1. Yoshikai, N.; Iida, R.; Nakamura, E. Mechanism of Nucleophilic Substitution of Acyl Electrophiles using Lithium Organocuprates. Adv. Synth. Catal. 2008, 350, 1063-1072.

  1. Hajra, A.; Yoshikai, N.; Nakamura, E. Aminohydroxyphosphine Ligands for Copper-Catalyzed Enantioselective Conjugate Addition of Organozinc Reagents. Org. Lett. 2006, 8, 4153-4155.

  1. Yoshikai, N.; Yamanaka, M.; Ojima, I.; Morokuma, K.; Nakamura, E. Bimetallic Synergism in Alkyne Silylformylation Catalyzed by Cobalt-Rhodium Mixed-Metal Cluster. Organometallics 2006, 25, 3867-3875.

  1. Yoshikai, N.; Yamashita, T.; Nakamura, E. Mechanism of Remote Conjugate Addition of a Lithium Organocuprate to Polyconjugated Carbonyl Compounds. Chem. Asian. J. 2006, 1, 322-330.

  1. Norinder, J.; Bäckvall, J.-E.; Yoshikai, N.; Nakamura, E. Unusual Homo-Coupling in the Reaction of Diorganocuprates with an Allylic Halide. Organometallics 2006, 25, 2129-2132.

  1. Yoshikai, N.; Mashima, H.; Nakamura, E. Nickel-Catalyzed Cross-Coupling Reaction of Aryl Fluorides and Chlorides with Grignard Reagents under Nickel/Magnesium Bimetallic Cooperation. J. Am. Chem. Soc. 2005, 127, 17978-17979.

  1. Yoshikai, N.; Yamashita, T.; Nakamura, E. Mechanism of Remote Conjugate Addition of a Lithium Organocuprate to a Polyconjugated Carbonyl Compound. Angew. Chem. Int. Ed. 2005, 44, 4721-4723.

  1. Ammal, S. C.; Yoshikai, N.; Inada, Y.; Nishibayashi, Y.; Nakamura, E. Synergistic Dimetallic Effects in Propargylic Substitution Reaction Catalyzed by Thiolate-Bridged Diruthenium Complex. J. Am. Chem. Soc. 2005, 127, 9428-9438.

  1. Kinoshita, N.; Marx, K. H.; Tanaka, K.; Tsubaki, K.; Kawabata, T.; Yoshikai, N.; Nakamura, E. Enantioselective Allylic Substitution of Cinnamyl Esters Catalyzed by Iridium-Chiral Aryl Phosphite Complex: Conspicuous Change in the Mechanistic Spectrum by a Counter Cation and Solvent. J. Org. Chem. 2004, 69, 7960-7964.

  1. Yoshikai, N.; Ammal, S. C.; Nakamura, E. L-shaped Three-center Two-electron (C-C-C)+ Bonding Array. J. Am. Chem. Soc. 2004, 126, 12941-12948.

  1. Yoshikai, N.; Nakamura, E. Mechanism of Substitution Reaction on sp2-Carbon Center with Lithium Organocuprate. J. Am. Chem. Soc. 2004, 126, 12264-12265.

  1. Nakamura, E.; Yoshikai, N. On the Mechanism of “Higher-Order Cuprate”, Alias Lipshutz Cuprate. Bull. Chem. Soc. Jpn. 2004, 77, 1-12.

  1. Yoshikai, N.; Nakamura, E. Theoretical Studies on Diastereo- and Enantioselective Rhodium-Catalyzed Cyclization of Diazo Compound via Intramolecular C-H Bond Insertion. Adv. Synth. Catal. 2003, 345, 1159-1171.

  1. Nakamura, E.; Yoshikai, N.; Yamanaka, M. Mechanism of C-H Bond Activation/C-C Bond Formation Reaction between Diazo Compound and Alkane Catalyzed by Dirhodium Tetracarboxylate. J. Am. Chem. Soc. 2002, 124, 7181-7192.

  1. Nakamura, M.; Yoshikai, N.; Nakamura, E. Carbozincation of Dipolar Trimethylenemethane. A New Route to Functionalized Organozinc Reagents. Chem. Lett. 2002, 146-147.

  1. Nakamura, M.; Yoshikai, N.; Toganoh, M.; Nakamura, E. [3 + 3] Cycloaddition of Dipolar Trimethylenemethane with Active Methylene Compound. Synlett 2001, 1030-1033.

  1. Nakamura, E.; Yamanaka, M.; Yoshikai, N.; Mori, S. Kinetic Reactivity of “Higher Order Cuprate” in SN2 Alkylation Reaction. Angew. Chem. Int. Ed. 2001, 40, 1935-1938.

Book Chapters

  1. Organocobalt Complexes in C–H Activation, Yoshikai, N. In Comprehensive Organometallic Chemistry IV, Mayer, K.; O’Hare, D.; Parkin, G. Eds., Elsevier, 2022.

  1. Cobalt-Catalyzed Asymmetric C–H Functionalization, Yoshikai, N. In Handbook of C–H Functionalization, Maiti, D. Ed., Wiley, 2022.

  1. Cobalt-Catalyzed C–H Activation, Yoshikai, N. In Chemistry of Organocobalt Compounds, Gosmini, C.; Marek, I. Eds., Wiley, 2022.

  1. Benzo[b]thiophenes, Yoshikai, N.; Rayner, C. M.; Graham, M. A. In Science of Synthesis Knowledge Updates, (2020) 2, 53 .

  1. Cobalt-Catalysed C–H Functionalization, Yoshikai, N. In Cobalt Catalysis in Organic Synthesis: Methods and Reactions, Hapke, M.; Hilt, G. Eds., Wiley, 2020.

  1. Hydroarylation of Alkynes and Alkenes using Group 7–9 First Row Transition Metal Catalysts, Yoshikai, N. In Catalytic Hydroarylation of Carbon-Carbon Multiple Bonds, Ackermann, L.; Gunnoe, T. B.; Habgood, L. G. Eds., Wiley, 2018.

  1. Heterocycle Synthesis via Co-Catalyzed C–H Activation/Functionalization, Yoshikai, N. In Transition Metal-Catalyzed Heterocycle Synthesis via C–H Activation, Wu, X.-F. Ed., Wiley, 2016.

  1. Iron-Catalyzed C–C Bond Formation with C–H Bond Activation, Yoshikai, N. In The Chemistry of Organoiron Compounds, Rappoport, Z.; Marek, I. Eds., Wiley, 2014.

  1. Theory of Organocopper-Mediated Reactions, Nakamura, E.; Yoshikai, N. In The Chemistry of Organocopper Compounds, Rappoport, Z.; Marek, I. Eds., Wiley, 2009.