Yoshikai Group

Graduate School of Pharmaceutical Sciences, Tohoku University 東北大学大学院薬学研究科・分子設計化学分野

Our group is committed to the development and mechanistic study of novel molecular transformations for organic synthesis. Our research programs are driven by a desire to uncover and understand unprecedented chemical reactivities and to exploit such reactivities in the design and development of efficient and selective organic reactions.


2023.9 築地健人さんと岩田真輝さんが日本化学会東北支部80周年記念国際会議でポスター賞を受賞しました.

2023.9 築地健人さんがGP-Chem(東北大学統合化学国際共同大学院)キックオフシンポジウムでポスター賞を受賞しました.

2023.4 浅沼隼人さんが第34回万有仙台シンポジウムでポスター賞を受賞しました.

2023.4 長田透弥さんが日本薬学会第134年会でポスター賞を受賞しました.

2023.4  Dr. Kanemoto has been featured in Angewandte Chemie.

2023.4 A new paper by Tsukiji, Hayakawa et al. has been published in Asian J. Org. Chem.

2023.3 New papers by Asanuma, Kanemoto et al. and Saito et al. have been published in Angewandte Chemie.


Earth-Abundant Metal Catalysis

C–H activations, cycloadditions, asymmetric catalysis

Heterocyclic Chemistry

Novel synthetic methods for heterocycles relevant to pharmaceuticals and materials

Hypervalent Iodine Chemistry

Novel reactivity and synthetic applications

Recent Publications

Full Publication List

Zinc-Mediated Diastereoselective Annulation of Cyclopropanols with Alkylidenemalononitriles via Enolized Homoenolate

Tsukiji, K.; Hayakawa, T.; Kanemoto, K.; Yoshikai, N. Asian J. Org. Chem. 2023, e202300114.

Site-Selective C–H Alkenylation of N-Heteroarenes by Ligand-Directed Co/Al and Co/Mg Cooperative Catalysis

Saito, Y.; Kikuchi, J.; Wang, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2023, e202301006.

N-(Morpholine-4-dithio)phthalimide: A Shelf-Stable, Bilateral Platform Molecule Enabling Access to Diverse Unsymmetrical Disulfides

Asanuma, H.; Kanemoto, K.; Watanabe, T.; Fukuzawa, S. Angew. Chem. Int. Ed. 2023, e202219156.

Science of Synthesis Base-Metal Catalysis

Science of Synthesis Base-Metal Catalysis; Yoshikai, N. Ed.; Thieme; Stuttgart, 2022.

Exploring New Reactions and Syntheses of Trivalent Iodine Compounds

Yoshikai, N. J. Synth. Org. Chem. Jpn. 2022, 80, 1011-1018.

Stereoselective Synthesis of β-Alkoxy-β-amido Vinylbenziodoxoles via Iodo(III)etherification of Ynamides

Kikuchi, J.; Maesaki, K.; Sasaki, S.; Wang, W.; Ito, S.; Yoshikai, N. Org. Lett. 2022, 24, 6914-6918.


KIKUCHI Jun 菊池 隼

Assistant Professor


ZHOU Liejin 周 列錦

Postdoctoral Fellow


ASANUMA Hayato 浅沼 隼人

Graduate Student (D1)/JSPS DC1


ARAKAWA Chisaki 荒川 千紗貴

Graduate Student (M2)


TSUKIJI Kento 築地 健人

Graduate Student (M2)


NAGATA Toya 長田 透弥

Graduate Student (M2)



Graduate Student (M2)


ABE Shohei 阿部 将平

Graduate Student (M1)


OTSUKI Shinya 大槻 真也

Graduate Student (M1)


SASAKI Shuma 佐々木 脩磨

Graduate Student (M1)


NAKAJIMA Roi 中島 呂維

Graduate Student (M1)


IWATA Masaki 岩田 真輝

Graduate Student (M1)


TAKAMI Yuzuki 鷹見 優月

Undergraduate Student (B4)


NAMBU Ryoga 南部 凌我

Undergraduate Student (B4)


MACHINAGA Tomoya 町永 智哉

Undergraduate Student (B4)


MOROHASHI Shunya 諸橋 駿矢

Undergraduate Student (B4)

YOSHIKAI Naohiko 吉戒 直彦

YOSHIKAI Naohiko 吉戒 直彦


Professional Appointment

2021-Present: Professor, Tohoku University

2016-2021: Associate Professor (tenured), NTU Singapore

2009-2016: Assistant Professor, NTU Singapore

2009-2014: NRF Research Fellow, National Research Foundation (Singapore)

2005-2009: Assistant Professor, The University of Tokyo


2005 Ph.D. in Chemistry, The University of Tokyo (Prof. E. Nakamura)

2002 M.Sc. in Chemistry, The University of Tokyo (Prof. E. Nakamura)

2000 B.Sc. in Chemistry, The University of Tokyo (Prof. E. Nakamura)

2002-2005: JSPS Fellow

2002: Visiting Student, Stockholm University (Prof. Jan Bäckvall)


2022: Mukaiyama Award

2020: TCI-SNIC Industry Award in Synthetic Chemistry

2015: Asian Core Program (ACP) Lectureship (from Thailand)

2014: Asian Core Program (ACP) Lectureship (from China and Korea)

2014: The 63rd Chemical Society of Japan Award for Young Chemists

2014: SPMS Young Researcher Awards

2011: Asian Core Program Lectureship (from Japan)

2011: Thieme Chemistry Journals Award

2008: Takasago Award in Synthetic Organic Chemistry, Society of Synthetic Organic Chemistry in Japan

2007: Inoue Research Award for Young Scientists, Inoue Research Foundation

Download CV


吉戒 直彦


980-8578 仙台市青葉区荒巻字青葉6-3

E-mail: naohiko.yoshikai.c5@tohoku.ac.jp; Tel: 022-795-6812

Naohiko Yoshikai

Graduate School of Pharmaceutical Sciences

Tohoku University

6-3 Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan

E-mail: naohiko.yoshikai.c5@tohoku.ac.jp; Tel: +81-22-795-6812