Yoshikai Group

Graduate School of Pharmaceutical Sciences, Tohoku University 東北大学大学院薬学研究科・分子設計化学分野

Our group is committed to the development and mechanistic study of novel molecular transformations for organic synthesis. Our research programs are driven by a desire to uncover and understand unprecedented chemical reactivities and to exploit such reactivities in the design and development of efficient and selective organic reactions.

News

2024.2. A paper on the new reaction between organoiodine(III) compounds and arynes by Arakawa, Kanemoto et al. has been published in J. Am. Chem. Soc.

2024.1. A paper on the N-terminal-specific modification of peptides by Machida and Kanemoto has been published in Angew. Chem. Int. Ed. プレスリリース

2024.1 Kento Tsukiji has received Poster Award at 4th Bowei Research Conference.

2023.12 岩田真輝さんが第38回有機合成化学若手研究者の仙台セミナー・ショートトークの部でセミナー賞を受賞しました.

2023.11 A paper on the selective synthesis of aminodisulfides by Asanuma and Kanemoto has been published in Org. Lett. See the cover art

2023.10 New members have joined our group.

2023.9 A new paper by Sasaki et al. has been published in J. Org. Chem.

2023.9  築地健人さんが有機金属化学討論会で ポスター賞を受賞しました.

2023.9  築地健人さん岩田真輝さんが日本化学会東北支部80周年記念国際会議でポスター賞を受賞しました.

2023.9 築地健人さんがGP-Chem(東北大学統合化学国際共同大学院)キックオフシンポジウムでポスター賞を受賞しました.

Research

Earth-Abundant Metal Catalysis

C–H activations, cycloadditions, asymmetric catalysis

Heterocyclic Chemistry

Novel synthetic methods for heterocycles relevant to pharmaceuticals and materials

Hypervalent Iodine Chemistry

Novel reactivity and synthetic applications

Recent Publications

Full Publication List

Carboiodanation of Arynes: Organoiodine(III) Compounds as Nucleophilic Organometalloids

Arakawa, C.; Kanemoto, K.; Nakai, K.; Wang, C.; Morohashi, S.; Kwon, E.; Ito, S.; Yoshikai, N. J. Am. Chem. Soc. 2024, DOI 10.1021/jacs.3c11524

N-Terminal-Specific Dual Modification of Peptides through Copper-Catalyzed [3+2] Cycloaddition

Machida, H.; Kanemoto, K. Angew. Chem. Int. Ed. 2024, e202320012.

Zinc-Mediated Diastereoselective Annulation of Cyclopropanols with Alkylidenemalononitriles via Enolized Homoenolate

Tsukiji, K.; Hayakawa, T.; Kanemoto, K.; Yoshikai, N. Asian J. Org. Chem. 2023, 12, e202300114 (Prof. Keiji Maruoka’s 70th birthday collection).

Site-Selective C–H Alkenylation of N-Heteroarenes by Ligand-Directed Co/Al and Co/Mg Cooperative Catalysis

Saito, Y.; Kikuchi, J.; Wang, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2023, 62, e202301006.

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KIKUCHI Jun 菊池 隼

Assistant Professor

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ASANUMA Hayato 浅沼 隼人

Graduate Student (D1)/JSPS DC1

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IKESHITA Daichi 池下 大智

Graduate Student (D1)

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ARAKAWA Chisaki 荒川 千紗貴

Graduate Student (M2)

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TSUKIJI Kento 築地 健人

Graduate Student (M2)

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NAGATA Toya 長田 透弥

Graduate Student (M2)

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YOSHIMURA Ken 吉村 健

Graduate Student (M2)

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ABE Shohei 阿部 将平

Graduate Student (M1)

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OTSUKI Shinya 大槻 真也

Graduate Student (M1)

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SASAKI Shuma 佐々木 脩磨

Graduate Student (M1)

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NAKAJIMA Roi 中島 呂維

Graduate Student (M1)

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IWATA Masaki 岩田 真輝

Graduate Student (M1)

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TAKAMI Yuzuki 鷹見 優月

Undergraduate Student (B4)

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NAMBU Ryoga 南部 凌我

Undergraduate Student (B4)

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MACHINAGA Tomoya 町永 智哉

Undergraduate Student (B4)

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MOROHASHI Shunya 諸橋 駿矢

Undergraduate Student (B4)

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ATARASHI Mao 新敷 茉央

Undergraduate Student (B3)

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OHNO Hibiki 大野 響己

Undergraduate Student (B3)

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KAMIOKA Shungo 上岡 駿吾

Undergraduate Student (B3)

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TOIZUMI Yugo 戸泉 友吾

Undergraduate Student (B3)

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YAMAMOTO Riku 山本 璃玖

Undergraduate Student (B3)

YOSHIKAI Naohiko 吉戒 直彦

YOSHIKAI Naohiko 吉戒 直彦

Professor

Professional Appointment

2021-Present: Professor, Tohoku University

2016-2021: Associate Professor (tenured), NTU Singapore

2009-2016: Assistant Professor, NTU Singapore

2009-2014: NRF Research Fellow, National Research Foundation (Singapore)

2005-2009: Assistant Professor, The University of Tokyo

Education

2005 Ph.D. in Chemistry, The University of Tokyo (Prof. E. Nakamura)

2002 M.Sc. in Chemistry, The University of Tokyo (Prof. E. Nakamura)

2000 B.Sc. in Chemistry, The University of Tokyo (Prof. E. Nakamura)


2002-2005: JSPS Fellow

2002: Visiting Student, Stockholm University (Prof. Jan Bäckvall)

Awards/Recognition

2022: Mukaiyama Award

2020: TCI-SNIC Industry Award in Synthetic Chemistry

2015: Asian Core Program (ACP) Lectureship (from Thailand)

2014: Asian Core Program (ACP) Lectureship (from China and Korea)

2014: The 63rd Chemical Society of Japan Award for Young Chemists

2014: SPMS Young Researcher Awards

2011: Asian Core Program Lectureship (from Japan)

2011: Thieme Chemistry Journals Award

2008: Takasago Award in Synthetic Organic Chemistry, Society of Synthetic Organic Chemistry in Japan

2007: Inoue Research Award for Young Scientists, Inoue Research Foundation

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Contact

吉戒 直彦

東北大学大学院薬学研究科・分子設計化学分野

980-8578 仙台市青葉区荒巻字青葉6-3

E-mail: naohiko.yoshikai.c5@tohoku.ac.jp; Tel: 022-795-6812

Naohiko Yoshikai

Graduate School of Pharmaceutical Sciences

Tohoku University

6-3 Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan

E-mail: naohiko.yoshikai.c5@tohoku.ac.jp; Tel: +81-22-795-6812