Hexadehydro Diels–Alder/Alkynyliodanation Cascade: A Highly Regioselective Entry to Polycyclic Aromatics
Morohashi, S.; Zhou, L.; Kanemoto, K.; Kwon, E.; Yoshikai, N. Org. Lett. DOI:10.1021/acs.orglett.5c00956
Diazomethyl-λ3-iodane meets aryne: dipolar cycloaddition and C-to-N iodane shift leading to indazolyl-λ3-iodanes
Otsuki, S.; Kanemoto, K.; Martos, D. C.; Kwon, E.; Wencel-Delord, J.; Yoshikai, N. Chem. Sci. DOI:10.1039/D5SC00266D
Stable and responsive atropisomerism around a carbon–iodine bond
Abe, S.; Kikuchi, J.; Matsumoto, A.; Yoshikai, N. Chem DOI:10.1016/j.chempr.2025.102527
A versatile entry to unnatural, disulfide-linked amino acids and peptides through the disulfuration of azlactones
Iwata, M.; Takami, Y.; Asanuma, H.; Hosono, K.; Ohno, H.; Yoshikai, N.; Kanemoto, K. Chem. Sci. 2025, 10.1039/D4SC07187E.
Diazomethyl-λ3-iodane Meets Aryne: Dipolar Cycloaddition and C-to-N Iodane Shift Leading to Indazolyl-λ3-iodanes
Otsuki, S.; Kanemoto, K.; Martos, D. C.; Kwon, E.; Wencel-Delord, J.; Yoshikai, N. ChemRxiv DOI:10.26434/chemrxiv-2024-dn8c5
Stable and responsive atropisomerism around a carbon–iodine bond
Abe, S.; Kikuchi, J.; Matsumoto, A.; Yoshikai, N. ChemRxiv DOI:10.26434/chemrxiv-2024-t16qt
Stereoselective Hydroxyallylation of Cyclopropenes with Cyclopropanols via NHC Catalysis of Transient Organozinc Species
Tsukiji, K.; Matsumoto, A.; Kanemoto, K.; Yoshikai, N. Angew. Chem. Int. Ed. 2024, 63, e202412456.
Three-component Friedel–Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(III) electrophile
Kikuchi, J.; Nagata, T.; Ito, S.; Yoshikai, N. Org. Chem. Front. 2024, 11, 3072-3079.
Amino- and Alkoxybenziodoxoles: Facile Preparation and Use as Arynophiles
Kanemoto, K.; Yoshimura, K.; Ono, K.; Ding, W.; Ito, S.; Yoshikai, N. Chem. Eur. J. 2024, 30, e202400894.
Three-component N-alkenylation of azoles with alkynes and iodine(III) electrophile: synthesis of multisubstituted N-vinylazoles
Kikuchi, J.; Nakajima, R.; Yoshikai, N. Beilstein J. Org. Chem. 2024, 20, 891-897.
1,3-Dipolar Cycloaddition of Polycyclic Aromatic Azomethine Ylides and Alkynylbenziodoxoles for Synthesis of Functional Dibenzoullazines
Han, H.; Goh, G. W. Z.; Li, Y.; Yoshikai, N.; Ito, S. Chin. J. Chem. 2024, 42, 1079-1083.
Carboiodanation of Arynes: Organoiodine(III) Compounds as Nucleophilic Organometalloids
Arakawa, C.; Kanemoto, K.; Nakai, K.; Wang, C.; Morohashi, S.; Kwon, E.; Ito, S.; Yoshikai, N. J. Am. Chem. Soc. 2024, 146, 3910-3919.
N-Terminal-Specific Dual Modification of Peptides through Copper-Catalyzed [3+2] Cycloaddition
Machida, H.; Kanemoto, K. Angew. Chem. Int. Ed. 2024, e202320012.
Amination of N-(Organodithio)phthalimides for the Modular Synthesis of Aminodisulfides
Asanuma, H.; Kanemoto, K. Org. Lett. 2024, 26, 438-443.
Stereoselective Approach to Multisubstituted Enolates from Unactivated Alkynes: Oxyalkylidenation of Alkynyl Ketone Enolates with Aldehydes
Sasaki, S.; Kikuchi, J.; Ito, S.; Yoshikai, N. J. Org. Chem. 2023, 88, 14096-14104.
Zinc-Mediated Diastereoselective Annulation of Cyclopropanols with Alkylidenemalononitriles via Enolized Homoenolate
Tsukiji, K.; Hayakawa, T.; Kanemoto, K.; Yoshikai, N. Asian J. Org. Chem. 2023, 12, e202300114 (Prof. Keiji Maruoka’s 70th birthday collection).
Site-Selective C–H Alkenylation of N-Heteroarenes by Ligand-Directed Co/Al and Co/Mg Cooperative Catalysis
Saito, Y.; Kikuchi, J.; Wang, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2023, 62, e202301006.
N-(Morpholine-4-dithio)phthalimide: A Shelf-Stable, Bilateral Platform Molecule Enabling Access to Diverse Unsymmetrical Disulfides
Asanuma, H.; Kanemoto, K.; Watanabe, T.; Fukuzawa, S. Angew. Chem. Int. Ed. 2023, 62, e202219156.
Science of Synthesis Base-Metal Catalysis
Science of Synthesis Base-Metal Catalysis; Yoshikai, N. Ed.; Thieme; Stuttgart, 2022.
Exploring New Reactions and Syntheses of Trivalent Iodine Compounds
Yoshikai, N. J. Synth. Org. Chem. Jpn. 2022, 80, 1011-1018.
Stereoselective Synthesis of β-Alkoxy-β-amido Vinylbenziodoxoles via Iodo(III)etherification of Ynamides
Kikuchi, J.; Maesaki, K.; Sasaki, S.; Wang, W.; Ito, S.; Yoshikai, N. Org. Lett. 2022, 24, 6914-6918.
Diastereoselective Conversion of Cyclopropanols to Cyclopentane-1,3-diols via Aldol Dimerization of Zinc Homoenolates
Tsukiji, K.; Sekiguchi, Y.; Kanemoto, K.; Yoshikai, N. Chem. Lett. 2022, 51, 1012-1014.
Cobalt Selectively Annulates
Kikuchi, J.; Yoshikai, N. Nat. Synth. 2022, 1, 674-675 (News & Views).
Cobalt-Catalyzed Carbo- and Hydrocyanation of Alkynes via C-CN Bond Activation
Wang, C.-S.; Yu, Y.; Sunada, Y.; Wang, C.; Yoshikai, N. ACS Catal. 2022, 12, 4054-4066.
Organocobalt Complexes in C–H Activation
Yoshikai, N. In Comprehensive Organometallic Chemistry IV; Mayer, K.; O’Hare, D.; Parkin, G. Eds.; Elsevier; Kidlington, UK, 2022; Vol. 7, pp. 759-815.
Zinc-Mediated Hydroxyallylation of Aldehydes with Cyclopropanols: Direct Access to Vicinal anti-sec,tert-Diols via Enolized Homoenolate
Sekiguchi, Y.; Yoshikai, N. Org. Lett. 2022, 24, 960-965.
Cobalt-Catalyzed Asymmetric C–H Functionalization
Yoshikai, N. In Handbook of C–H Functionalization, Maiti, D. Ed., Wiley, 2022.
Regio- and Stereoselective Synthesis of Enol Carboxylate, Phosphate, and Sulfonate Esters via Iodo(III)functionalization of Alkynes
Wang, C.-S.; Tan, P. S. L.; Ding, W.; Ito, S.; Yoshikai, N. Org. Lett. 2022, 24, 430-434.
Cobalt-Catalyzed C–H Activation
Yoshikai, N. In Chemistry of Organocobalt Compounds, Gosmini, C.; Marek, I. Eds., Wiley, In Press.
Zinc-Mediated Hydroxyallylation of Aldehydes with Cyclopropanols: Direct Access to Vicinal anti-sec,tert-Diols via Enolized Homoenolate
Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI 10.26434/chemrxiv-2021-swc95.
Ritter-Type Iodo(III)amidation of Unactivated Alkynes for the Stereoselective Synthesis of Multisubstituted Enamides
Chai, J.; Ding, W.; Wang, C.; Ito, S.; Wu, J.; Yoshikai, N. Chem. Sci. 2021, 12, 15128-15133.
Ritter-Type Iodo(III)amidation of Unactivated Alkynes for the Stereoselective Synthesis of Multisubstituted Enamides
Chai, J.; Ding, W.; Ito, S.; Wu, J.; Yoshikai, N. ChemRxiv 2021, DOI 10.33774/chemrxiv-2021-c2ftp.
Zinc-Catalyzed β-Functionalization of Cyclopropanols via Enolized Homoenolate
Sekiguchi, Y.; Yoshikai, N. J. Am. Chem. Soc. 2021, 143, 18400-18405.
Zinc-Catalyzed β-Allylation of Cyclopropanols via Enolized Homoenolate
Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI 10.33774/chemrxiv-2021-4jlsp.
Nickel-Catalyzed Ring-Opening Allylation of Cyclopropanols via Homoenolate
Sekiguchi, Y.; Lee, Y. Y.; Yoshikai, N. Org. Lett. 2021, 23, 5993-5997.
Enantioselective Conjugate Addition of Catalytically Generated Zinc Homoenolate
Sekiguchi, Y.; Yoshikai, N. J. Am. Chem. Soc. 2021, 143, 4775-4781.
Enantioselective Conjugate Addition of Catalytically Generated Zinc Homoenolate
Sekiguchi, Y.; Yoshikai, N. ChemRxiv 2021, DOI 10.26434/chemrxiv.13607438.v1.
Robust Cobalt Catalyst for Nitrile/Alkyne [2+2+2] Cycloaddition: Synthesis of Polyarylpyridines and Their Mechanochemical Cyclodehydrogenation to Nitrogen-Containing Polyaromatics
Wang, C.-S.; Sun, Q.; Garcia, F.; Wang, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2021, 60, 9627-9634.
Cobalt-Catalyzed Intermolecular [2+2+2] Cycloaddition of Nitriles and Alkynes: Facile Synthesis of Polyarylpyridines and Their Mechanochemical Cyclodehydrogenation to Nitrogen-Containing Polyaromatics
Wang, C.-S.; Sun, Q.; Garcia, F.; Wang, C.; Yoshikai, N. ChemRxiv 2021, DOI 10.26434/chemrxiv.13465697.v1.
Iodo(III)-Meyer-Schuster Rearrangement of Propargylic Alcohols Promoted by Benziodoxole Triflate
Laskar, R. A.; Ding, W.; Yoshikai, N. Org. Lett. 2021, 23, 1113-1117.
Metal-Catalyzed Transformations of Cyclopropanols via Homoenolates
Sekiguchi, Y.; Yoshikai, N. Bull. Chem. Soc. Jpn. 2021, 1, 265-280.
Iron-Catalyzed Remote C-H Alkylation of 8-Amidoquinolines with Cycloalkanes
Xu, W.; Wu, M.; Yoshikai, N. Synthesis 2020, published online.
Fluorobenziodoxole-BF3 Reagent for Iodo(III)etherification of Alkynes in Ethereal Solvent
Chai, J.; Ding, W.; Wu, J.; Yoshikai, N. Chem. Asian J. 2020, 15, 2166-2169.
Site-selective aromatic C-H λ3-iodanation with cyclic iodine(III) electrophile in solution and solid phases
Ding, W.; Wang, C.; Tan, J. R.; Ho, C. C.; León, F.; García, F.; Yoshikai, N. Chem. Sci. 2020, 11, 7356-7361.
Cobalt‐Catalyzed Intramolecular Hydroacylation Involving Cyclopropane Cleavage
Yang, J.; Mori, Y.; Yamanaka, M.; Yoshikai, N. Chem. Eur. J. 2020, 26, 8302-8307.
Stereoselective Access to Multisubstituted Vinyl Ethers via trans-Difunctionalization of Alkynes with Alcohols and Iodine(III) Electrophile
Ding, W.; Chai, J.; Wang, C.; Wu, J.; Yoshikai, N. J. Am. Chem. Soc. 2020, 142, 8619-8624.
Stereoselective Access to Multisubstituted Vinyl Ethers via trans-Difunctionalization of Alkynes with Alcohols and Iodine(III) Electrophile
Ding, W.; Chai, J.; Wu, J.; Yoshikai, N. ChemRxiv 2020, DOI 10.26434/chemrxiv.11770092.v1.
Cobalt/Lewis Acid Catalysis for Hydrocarbofunctionalization of Alkynes via Cooperative C–H Activation
Wang, C.-S.; Di Monaco, S.; Thai, A. N.; Wang, C.; Yoshikai, N. J. Am. Chem. Soc. 2020, 142, 12878-12889.
Cobalt/Lewis Acid Catalysis for Hydrocarbofunctionalization of Alkynes via Cooperative C–H Activation
Wang, C.-S.; Di Monaco, S.; Thai, A. N.; Wang, C.; Yoshikai, N. ChemRxiv. 2020, DOI 10.26434/chemrxiv.11760519.v1.
Benzo[b]thiophenes
Yoshikai, N.; Rayner, C. M.; Graham, M. A. In Science of Synthesis Knowledge Updates, (2020) 2, 53.
Synthesis of Triphenylene-Fused Phosphole Oxides via C-H Functionalizations
Rahman, M. S.; Yoshikai, N. Beilstein J. Org. Chem. 2020, 16, 524-529.
Cobalt-Catalysed C–H Functionalization
Yoshikai, N. In Cobalt Catalysis in Organic Synthesis. Methods and Reactions, Hapke, M.; Hilt, G. Eds., Wiley, 2020.
Cobalt-Catalyzed, N–H Imine-Directed Arene C–H Benzylation with Benzyl Phosphates
Laskar, R. A.; Yoshikai, N. J. Org. Chem. 2019, 84, 13172-13178.
Cobalt-Catalyzed Hydroacylative Dimerization of Allenes Leading to Skipped Dienes
Ding, W.; Ho, Y. K. T.; Okuda, Y.; Wijaya, K. C.; Tan, Z. H.; Yoshikai, N. Org. Lett. 2019, 21, 6173-6178.
Cobalt-Catalyzed Tandem Radical Cyclization/C–C Coupling Initiated by Directed C–H Activation
Sun, Q.; Yoshikai, N. Org. Lett. 2019, 21, 5238-5242.
Synthesis and Properties of Phospha[5]helicenes Bearing Inner-Rim Phosphorus Center
Rahman, M. S.; Yoshikai, N. Org. Lett. 2019, 21, 3232-3236.
Cobalt-Catalyzed Enantioselective and Chemodivergent Addition of Cyclopropanols to Oxabicyclic Alkenes
Yang, J.; Sekiguchi, Y.; Yoshikai, N. ACS Catal. 2019, 9, 5638-5644.
Iron‐Catalyzed ortho C−H Arylation and Methylation of Pivalophenone N−H Imines
Xu, W.; Yoshikai, N. ChemSusChem 2019, 12, 3049-3053.
Pd‐Catalyzed Annulation of 1‐Halo‐8‐arylnaphthalenes and Alkynes Leading to Heptagon‐Embedded Aromatic Systems
Yan, J.; Rahman, M. S.; Yoshikai, N. Chem. Eur. J. 2019, 25, 9395-9399.
Cobalt-Catalyzed Regio- and Diastereoselective Formal [3+2] Cycloaddition between Cyclopropanols and Allenes
Yang, J.; Sun, Q.; Yoshikai, N. ACS Catal. 2019, 9, 1973-1978.
Stereocontrolled Synthesis of Halovinylbenziodoxoles via Hydro- and Iodochlorination of Ethynylbenziodoxoles
Wu, J.; Deng, X.; Yoshikai, N. Chem. Eur. J. 2019, 25, 7839-7842.
Cobalt-Catalyzed Intermolecular [2+2] Cycloaddition between Alkynes and Allenes
Ding, W.; Yoshikai, N. Angew. Chem. Int. Ed. 2019, 58, 2500-2504.
Photosensitized, Energy-Transfer-Mediated Cyclization of 2-(1-Arylvinyl)benzaldehydes to Anthracen-9-(10H)-ones
Ding, W.; Ho, C. C.; Yoshikai, N. Org. Lett. 2019, 21, 1202-1206.
Recent Advances in Enantioselective C-C Bond Formation via Organocobalt Species
Yoshikai, N. Synthesis 2019, 51, 135-145.
Divergent ring-opening coupling between cyclopropanols and alkynes under cobalt catalysis
Yang, J.; Shen, Y.; Lim, Y. J.; Yoshikai, N. Chem. Sci. 2018, 9, 6928-6934.
Cobalt-catalyzed directed ortho-methylation of arenes with methyl tosylate
Sun, Q.; Yoshikai, N. Org. Chem. Front. 2018, 7, 2214-2218.
Cobalt-Catalyzed Intramolecular Reactions between a Vinylcyclopropane and an Alkyne: Switchable [5+2] Cycloaddition and Homo-Ene Pathways
Wu, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2018, 57, 6558-6562.
Iron-Catalyzed Directed C–H Silylation of Pivalophenone N–H Imines
Xu, W.; Pek, J. H.; Yoshikai, N. Asian J. Org. Chem. 2018, 14, 1351-1354.
Cobalt-Catalyzed Directed C–H Alkenylation of Pivalophenone N–H Imine with Alkenyl Phosphates
Xu, W.; Yoshikai, N. Beilstein J. Org. Chem. 2018, 14, 709-715.
Cobalt-Catalyzed C(sp2)–H/C(sp3)–H Coupling via Directed C– H Activation and 1,5-Hydrogen Atom Transfer
Sun, Q.; Yoshikai, N. Org. Chem. Front. 2018, 5, 582-585.
Copper and Secondary Amine-Catalyzed Pyridine Synthesis from O-Acetyl Oximes and α,β-Unsaturated Aldehydes
Tan, W. W.; Wu, B.; Wei, Y.; Yoshikai, N. Org. Synth. 2018, 95, 1-14.
Hydroarylation of Alkynes and Alkenes using Group 7–9 First Row Transition Metal Catalysts
Yoshikai, N. In Catalytic Hydroarylation of Carbon-Carbon Multiple Bonds, Ackermann, L.; Gunnoe, T. B.; Habgood, L. G. Eds., Wiley, 2018.
Cobalt-Catalyzed, N–H Imine-Directed Hydroarylation of Styrenes
Xu, W.; Yoshikai, N. Org. Lett. 2018, 20, 1392-1395.
Phenanthrene Synthesis via Chromium-Catalyzed Annulation of 2-Biaryl Grignard Reagents and Alkynes
Yan, J.; Yoshikai, N. Org. Lett. 2017, 19, 6630-6633.
Benziodoxole Triflate as a Versatile Reagent for Iodo(III)cyclization of Alkynes
Wu, B.; Wu, J.; Yoshikai, N. Chem. Asian J. 2017, 12, 3123-3127.
Iron-Catalyzed C–C Bond Formation via Chelation-Assisted C–H Activation
Yoshikai, N. Isr. J. Chem. 2017, 57, 1117-1130.
Chromium-Catalyzed Migratory Arylmagnesiation of Unactivated Alkynes
Yan, J.; Yoshikai, N. Org. Chem. Front. 2017, 4, 1972-1975.
Synthesis of Donor-Acceptor-Type Benzo[b]phosphole and Naphtho[2,3-b]phosphole Oxides and Their Solvatochromic Properties
Yoshikai, N.; Santra, M.; Wu, B. Organometallics 2017, 20, 1392-1395.
Pivalophenone Imine as a Benzonitrile Surrogate for Directed C–H Bond Functionalization
Xu, W.; Yoshikai, N. Chem. Sci. 2017, 8, 5299-5304.
Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines
Tan, W. W.; Ong, Y. J.; Yoshikai, N. Angew. Chem. Int. Ed. 2017, 56, 8240-8244.
Versatile Telluracyclc Synthesis via the Sequential Electrophilic Telluration of C(sp2)–Zn and C(sp2)–H Bonds
Wu, B.; Melvina; Wu, X.; Yeow, E. K. L.; Yoshikai, N. Chem. Sci. 2017, 8, 4527-4532.
Directed C–H Alkenylation of Aryl Imines with Alkenyl Phosphates Promoted by a Cobalt–N-Heterocyclic Carbene Catalyst
Lee, P.-S.; Xu, W.; Yoshikai, N. Adv. Synth. Catal. 2017, 359, 4340-4347.
Cobalt-Catalyzed Enantio- and Diastereoselective Hydroacylation of Trisubstituted Alkenes
Yang, J.; Rérat, A.; Lim, Y. J.; Gosmini, C.; Yoshikai, N. Angew. Chem. Int. Ed. 2017, 56, 2449-2453.
Pd-Catalyzed, Ligand-Enabled Stereoselective 1,2-Iodine(III) Shift/1,1-Carboxyalkynylation of Alkynylbenziodoxoles
Wu, J.; Xu, K.; Hirao, H.; Yoshikai, N. Chem. Eur. J. 2017, 23, 1521-1525.
N–H Imine as a Powerful Directing Group for Cobalt-Catalyzed Olefin Hydroarylation
Xu, W.; Yoshikai, N. Angew. Chem. Int. Ed. 2016, 55, 12731-12735.
Cobalt-Catalyzed, Imine-Directed Olefin Hydroarylation under Grignard-Free Conditions
Xu, W.; Pek, J. H.; Yoshikai, N. Adv. Synth. Catal. 2016, 358, 2564-2568.
Pd-Catalyzed Conversion of Alkynyl-λ3-iodanes to Alkenyl-λ3-iodanes via Stereoselective 1,2-Iodine(III) Shift/1,1- Hydrocarboxylation
Wu, J.; Deng, X.; Hirao, H.; Yoshikai, N. J. Am. Chem. Soc. 2016, 138, 9105-9108.
Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes
Tan, W. W.; Yoshikai, N. J. Org. Chem. 2016, 81, 5566-5573.
Cobalt-Catalyzed Arylative Cyclization of Acetylenic Esters and Ketones with Arylzinc Reagents through 1,4-Cobalt Migration
Yan, J.; Yoshikai, N. ACS Catal. 2016, 6, 3738-3742.
Recent Developments in Synthetic Methods for Benzo[b]heteroles
Wu, B.; Yoshikai, N. Org. Biomol. Chem. 2016, 14, 5402-5416.
Cobalt-Catalyzed Annylation of Salicylaldehydes and Alkynes to Form Chromones and 4-Chromanones
Yang, J.; Yoshikai, N. Angew. Chem. Int. Ed. 2016, 55, 2870-2874.
Heterocycle Synthesis via Co-Catalyzed C–H Activation/Functionalization
Yoshikai, N. In Transition Metal-Catalyzed Heterocycle Synthesis via C–H Activation, Wu, X.-F. Ed., Wiley, 2016.
Cobalt-Catalyzed Alkenylzincation of Unfunctionalized Alkynes
Wu, J.; Yoshikai, N. Angew. Chem. Int. Ed. 2016, 55, 336-340.
One-Pot Benzo[b]phosphole Synthesis through Sequential Alkyne Arylmagnesiation, Electrophilic Trapping, and Intramolecular Phospha-Friedel–Crafts Cyclization
Wu, B.; Chopra, R.; Yoshikai, N. Org. Lett. 2015, 17, 5666-5669.
Modular Synthesis of Multisubstituted Furans through Palladium-Catalyzed Three-Component Condensation of Alkynylbenziodoxoles, Carboxylic Acids, and Imines
Wu, J.; Yoshikai, N. Angew. Chem. Int. Ed. 2015, 54, 11107-11111.
Ortho-C–H Benzylation of Aryl Imines with Benzyl Phosphates under Cobalt–Pyphos Catalysis
Xu, W.; Paira, R.; Yoshikai, N. Org. Lett. 2015, 17, 4192-4195.
Copper-Catalyzed Condensation of Imines and α-Diazo-β-dicarbonyl Compounds: Modular and Regiocontrolled Synthesis of Multisubstituted Pyrroles
Tan, W. W.; Yoshikai, N. Chem. Sci. 2015, 6, 6448-6455.
Conversion of 2-Iodobiaryls into 2,2-Diiodobiaryls via Oxidation- Iodination Sequences: A Versatile Route to Ladder-Type Heterofluorenes
Wu, B.; Yoshikai, N. Angew. Chem. Int. Ed. 2015, 54, 8736-8739.
Cobalt-Catalyzed Intermolecular Hydroacylation of Olefins through Chelation-Assisted Imidoyl C–H Activation
Yang, J.; Seto, Y. W.; Yoshikai, N. ACS Catal. 2015, 5, 3054-3057.
Cp*CoIII-Catalyzed C–H Activation of (Hetero)arenes: Expanding the Scope of Base-Metal-Catalyzed C–H Functionalization
Yoshikai, N. ChemCatChem 2015, 7, 732-734.
[Iron-Catalyzed Directed C2-Alkylation and Alkenylation of Indole with Vinylarenes and Alkynes
Wong, M. Y.; Yamakawa, T.; Yoshikai, N. Org. Lett. 2015, 17, 442-445.
Cobalt-Catalyzed Enantioselective Directed C–H Alkylation of Indoles with Styrenes
Lee, P.-S.; Yoshikai, N. Org. Lett. 2015, 17, 22-25.
Cobalt-Catalyzed Directed Alkylation of Olefinic C–H Bond with Primary and Secondary Alkyl Chlorides
Yamakawa, T.; Seto, Y. W.; Yoshikai, N. Synlett 2015, 26, 340-344.
Highly Linear-Selective Cobalt-Catalyzed Addition of Aryl Imines to Styrenes: Reversing Intrinsic Regioselectivity by Ligand Elaboration
Xu, W.; Yoshikai, N. Angew. Chem. Int. Ed. 2014, 53, 14166-14170.
Cobalt-Catalyzed Enantioselective Intramolecular Hydroacylation of Ketones and Olefins
Yang, J.; Yoshikai, N. J. Am. Chem. Soc. 2014, 136, 16748-16751.
Cobalt-Catalyzed C–C Bond-Forming Reactions via Chelation-Assisted C–H Activation
Yoshikai, N. J. Synth. Org. Chem. Jpn. 2014, 72, 1198-1206.
Pd(II)/Bu4NBr/DMSO Catalytic System for Practical Synthesis of Indoles and Pyrroles from Imines through Aerobic Dehydrogenative Cyclization
Tan, W. W.; Hou, X.; Yoshikai, N. Synthesis 2014, 46, 2727-2733.
Palladium-Catalyzed Condensation of N-Aryl Imines and Alkynylbenziodoxolones To Form Multisubstituted Furans
Lu, B.; Wu, J.; Yoshikai, N. J. Am. Chem. Soc. 2014, 136, 11598-11601.
Development of Cobalt-Catalyzed C–H Bond Functionalization Reactions
Yoshikai, N. Bull. Chem. Soc. Jpn. 2014, 87, 843-857.
Rhodium(III)-Catalyzed Directed peri-C–H Alkenylation of Anthracene Derivatives
Karthikeyan, J.; Yoshikai, N. Org. Lett. 2014, 16, 4224-4227.
Iron-Catalyzed C–C Bond Formation with C–H Bond Activation
Yoshikai, N. In The Chemistry of Organoiron Compounds, Rappoport, Z.; Marek, I. Eds., Wiley, 2014.
Cobalt-Catalyzed Chelation-Assisted Alkylation of Arenes with Primary and Secondary Alkyl Halides
Gao, K.; Yamakawa, T.; Yoshikai, N. Synthesis 2014, 46, 2024-2039 (Feature Article).
A Highly Modular One-Pot Multicomponent Approach to Functionalized Benzo[b]phosphole Derivative
Wu, B.; Santra, M.; Yoshikai, N. Angew. Chem. Int. Ed. 2014, 53, 7543-7546.
Cobalt-Catalyzed Addition of Arylzinc Reagents to Norbornene Derivatives through 1,4-Cobalt Migration
Tan, B.-H.; Yoshikai, N. Org. Lett. 2014, 16, 3392-3395.
ortho-Allylation of 1- Arylpyrazole with Allyl Phenyl Ether via Iron-Catalyzed C–H Bond Activation under Mild Conditions
Asako, S.; Norinder, J.; Ilies, L.; Yoshikai, N.; Nakamura, E. Adv. Synth. Catal. 2014, 356, 1481-1485.
Cobalt-Catalyzed Ortho-C–H Alkylation of 2-Arylpyridines via Ring-Opening of Aziridines
Gao, K.; Paira, R.; Yoshikai, N. Adv. Synth. Catal. 2014, 356, 1486-1490.
Cobalt-Catalyzed Directed Alkylation of Arenes with Primary and Secondary Alkyl Halides
Yoshikai, N.; Gao, K. Pure Appl. Chem. 2014, 86, 419-424.
Alkene Isomerization–Hydroarylation Tandem Catalysis: Indole C2-Alkylation with Aryl-Substituted Alkenes Leading to 1,1-Diarylalkanes
Yamakawa, T.; Yoshikai, N. Chem. Asian J. 2014, 9, 1242-1246.
Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization
Gao, K.; Yoshikai, N. Acc. Chem. Res. 2014, 47, 1208-1219.
Unraveling Organocuprate Complexity: Fundamental Insights into Intrinsic Group Transfer Selectivity in Alkylation Reactions
Rijs, N. J.; Yoshikai, N.; Nakamura, E.; O’Hair, R. A. J. J. Org. Chem. 2014, 79, 1320-1334.
Conformational Analysis of Single Perfluoroalkyl Chains by Single-Molecule Real-Time Transmission Electron Microscopic Imaging
Harano, K.; Takenaga, S.; Okada, S.; Niimi, Y.; Yoshikai, N.; Isobe, H.; Suenaga, K.; Kataura, H.; Koshino, M.; Nakamura, E. J. Am. Chem. Soc. 2014, 136, 466-473.
Versatile Synthesis of Benzothiophenes and Benzoselenophenes by Rapid Assembly of Arylzinc Reagents, Alkynes, and Elemental Chalcogens
Wu, B.; Yoshikai, N. Angew. Chem. Int. Ed. 2013, 52, 10496-10499.
Phenanthridine Synthesis through Iron-Catalyzed Intramolecular N-Arylation of O-Acetyl Oxime
Deb, I.; Yoshikai, N. Org. Lett. 2013, 15, 4254-4257.
Cobalt-Catalyzed Intramolecular Olefin Hydroarylation Leading to Dihydropyrroloindoles and Tetrahydropyridoindoles
Ding, Z.; Yoshikai, N. Angew. Chem. Int. Ed. 2013, 52, 8574-8578.
Cobalt-Catalyzed Branched-Selective Addition of Aromatic Ketimines to Styrenes under Room Temperature Conditions
Dong, J.; Lee, P.-S.; Yoshikai, N. Chem. Lett. 2013, 42, 1140-1142.
Cobalt-Catalyzed Ortho Alkylation of Aromatic Imines with Primary and Secondary Alkyl Halides
Gao, K.; Yoshikai, N. J. Am. Chem. Soc. 2013, 135, 9279-9282.
α-Palladation of Imines as Entry to Dehydrogenative Heck Reaction: Aerobic Oxidative Cyclization of N-Allylimines to Pyrroles
Chen, Z.; Lu, B.; Ding, Z.; Gao, K.; Yoshikai, N. Org. Lett. 2013, 15, 1966-1969.
Synthesis of Pyrroles, Indoles, and Carbazoles through Transition Metal-Catalyzed C–H Functionalization
Yoshikai, N.; Wei, Y. Asian J. Org. Chem. 2013, 2, 466-478.
Cobalt-Catalyzed ortho-Alkenylation of Aromatic Aldimines via Chelation-Assisted C–H Bond Activation
Yamakawa, T.; Yoshikai, N. Tetrahedron 2013, 69, 4459-4465.
Modular Pyridine Synthesis from Oximes and Enals through Synergistic Copper/Iminium Catalysis
Wei, Y.; Yoshikai, N. J. Am. Chem. Soc. 2013, 135, 3756-3759.
Annulation of α,β-Unsaturated Imines and Alkynes via Cobalt-Catalyzed Olefinic C–H Activation
Yamakawa, T.; Yoshikai, N. Org. Lett. 2013, 15, 196-199.
Aldimine-Directed Branched-Selective Hydroarylation of Styrenes
Lee, P.-S.; Yoshikai, N. Angew. Chem. Int. Ed. 2013, 52, 1240-1244.
Palladium-Catalyzed Aerobic Dehydrogenative Aromatization of Cyclohexanone Imines to Arylamines
Hajra, A.; Wei, Y.; Yoshikai, N. Org. Lett. 2012, 14, 5488-5491.
Synthesis of Polysubstituted Naphthalenes by Iron-Catalyzed [2+2+2] Annulation of Grignard Reagents with Alkynes
Ilies, L.; Matsumoto, A.; Kobayashi, M.; Yoshikai, N.; Nakamura, E. Synlett 2012, 2381-2384.
Cobalt-Catalyzed Addition of Arylzinc Reagents to Alkynes to Form ortho-Alkenylarylzinc Species through 1,4-Cobalt Migration
Tan, B.-H.; Dong, J.; Yoshikai, N. Angew. Chem. Int. Ed. 2012, 51, 9610-9614.
C2-Alkylation of N-Pyrimidylindole with Vinylsilanes via Cobalt-Catalyzed C-H Bond Activation
Ding, Z.; Yoshikai, N. Beilstein J. Org. Chem. 2012, 8, 1536-1542.
Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides
Gao, K.; Lee, P.-S.; Long, C.; Yoshikai, N. Org. Lett. 2012, 14, 4234-4237.
Nickel-Catalyzed Monosubsitution of Polyfluoroarenes with Organozinc Reagents Using Alkoxydiphosphine Ligand
Nakamura, Y.; Yoshikai, N.; Ilies, L.; Nakamura, E. Org. Lett. 2012, 14, 3316-3319.
Iron-Catalyzed Annulation Reaction of Arylindium Reagents and Alkynes to Produce Substituted Naphthalenes
Adak, L.; Yoshikai, N. Tetrahedron 2012, 68, 5167-5171.
Palladium-Catalyzed Aerobic Oxidative Cyclization of N-Aryl Imines: Indole Synthesis from Anilines and Ketones
Wei, Y.; Deb, I.; Yoshikai, N. J. Am. Chem. Soc. 2012, 134, 9098-9101.
Mild and Efficient C2-Alkenylation of Indoles with Alkynes Catalyzed by a Cobalt Complex
Ding, Z.; Yoshikai, N. Angew. Chem. Int. Ed. 2012, 51, 4698-4701.
Cobalt-Catalyzed Arylation of Aldimines via Directed C–H Bond Functionalization: Addition of 2-Arylpyridines and Self-Coupling of Aromatic Aldimines
Gao, K.; Yoshikai, N. Chem. Commun. 2012, 48, 4305-4307.
Iron-Catalyzed Nitrogen-Directed Coupling of Arene and Aryl Bromides Mediated by Metallic Magnesium
Ilies, L.; Kobayashi, M.; Matsumoto, A.; Yoshikai, N.; Nakamura, E. Adv. Synth. Catal. 2012, 354, 593-596.
Mechanisms of Nucleophilic Organocopper(I) Reactions
Yoshikai, N.; Nakamura, E. Chem. Rev. 2012, 112, 2339-2372.
Gas-Phase Reactivity of Group 11 Dimethylmetallates with Allyl Iodide
Rijs, N.; Yoshikai, N.; Nakamura, E.; O’Hair, R. A. J. J. Am. Chem. Soc. 2012, 134, 2569-2580.
Iron-Catalyzed C–H Bond Activation for the ortho-Arylation of Aryl Pyridines and Imines with Grignard Reagents
Yoshikai, N.; Asako, S.; Yamakawa, T.; Ilies, L.; Nakamura, E. Chem. Asian. J. 2011, 6, 3059-3065.
Cobalt-Catalyzed, Room-Temperature Addition of Aromatic Imines to Alkynes via Directed C–H Bond Activation
Lee, P.-S.; Fujita, T.; Yoshikai, N. J. Am. Chem. Soc. 2011, 133, 17283-17295.
Oxidative Cyclization of 2-Arylphenols to Dibenzofurans under Pd(II)/Peroxybenzoate Catalysis
Wei, Y.; Yoshikai, N. Org. Lett. 2011, 13, 5504-5507.
Cobalt-Catalyzed Preparation of Arylindium Reagents from Aryl and Heteroaryl Bromides
Adak, L.; Yoshikai, N. J. Org. Chem. 2011, 76, 7563-7568.
Cobalt–Phenanthroline Catalysts for the ortho Alkylation of Aromatic Imines under Mild Conditions
Gao, K.; Yoshikai, N. Angew. Chem. Int. Ed. 2011, 50, 6888-6892.
Cobalt-Catalyzed Alkenylation of Thiazoles with Alkynes via C–H Bond Functionalization
Ding, Z.; Yoshikai, N. Synthesis 2011, 2561-2566.
Cobalt-Catalyzed Coupling of Alkyl Grignard Reagent with Benzamide and 2-Phenylpyridine Derivatives through Directed C–H Bond Activation under Air
Chen, Q.; Ilies, L.; Yoshikai, N.; Nakamura, E. Org. Lett. 2011, 13, 3232-3234.
Cobalt-Catalyzed, Chelation-Assisted C-H Bond Functionalization
Yoshikai, N. Synlett 2011, 1047-1051.
Cobalt–Xantphos Catalyzed, LiCl-Mediated Preparation of Arylzinc Reagents from Aryl Iodides, Bromides, and Chlorides
Jin, M.-Y.; Yoshikai, N. J. Org. Chem. 2011, 76, 1972-1978 (Featured Article).
Regioselectivity-Switchable Hydroarylation of Styrenes
Gao, K.; Yoshikai, N. J. Am. Chem. Soc. 2011, 133, 400-402.
Nickel-Catalyzed, Directing Group-Assisted [2 + 2 + 2] Cycloaddition of Imine and Alkynes
Adak, L.; Chan, W. C.; Yoshikai, N. Chem. Asian. J. 2011, 6, 359-362.
Cobalt-Catalyzed Addition of Azoles to Alkynes
Ding, Z.; Yoshikai, N. Org. Lett. 2010, 12, 4180-4183.
Cobalt-Catalyzed Hydroarylation of Alkynes through Chelation-Assisted C-H Bond Activation
Gao, K.; Lee, P.-S.; Fujita, T.; Yoshikai, N. J. Am. Chem. Soc. 2010, 132, 12249-12251.
Low-Valent Iron-Catalyzed C–C Bond Formation— Addition, Substitution, and C–H Bond Activation
Nakamura, E.; Yoshikai, N. J. Org. Chem. 2010, 75, 6061-6067.
Iron-Catalyzed, Directed Oxidative Arylation of Olefins with Organozinc and Grignard Reagents
Ilies, L.; Okabe, J.; Yoshikai, N.; Nakamura, E. Org. Lett. 2010, 12, 2838-2840.
Ligand Exchange Reactions in Cu(III) Complexes: Mechanistic Insights by Combined NMR and DFT Studies
Gärtner, T.; Yoshikai, N.; Neumeier, M.; Nakamura, E.; Gschwind, R. M. Chem. Commun. 2010, 46, 4625-4626.
Iron-Catalyzed C-C Bond Formation at α-Position of Aliphatic Amines via C-H Bond Activation through 1,5-Hydrogen Transfer
Yoshikai, N.; Mieczkowski, A.; Matsumoto, A.; Ilies, L.; Nakamura, E. J. Am. Chem. Soc. 2010, 132, 5568-5569.
Iron-Catalyzed Direct Arylation of Aryl Pyridines and Imines Using Oxygen as an Oxidant
Yoshikai, N.; Matsumoto, A.; Norinder, J.; Nakamura, E. Synlett 2010, 313-316.
Hydroxyphosphine Ligand for Nickel-Catalyzed Cross-Coupling through Nickel/Magnesium Bimetallic Cooperation
Yoshikai, N.; Matsuda, H.; Nakamura, E. J. Am. Chem. Soc. 2009, 131, 9590-9599.
Enantioselective Copper-Catalyzed Allylic Substitution with Aminohydroxyphosphine Ligand
Yoshikai, N.; Miura, K.; Nakamura, E. Adv. Synth. Catal. 2009, 351, 1014-1018.
Iron-Catalyzed Chemoselective ortho Arylation of Aryl Imines by Directed C-H Bond Activation
Yoshikai, N.; Matsumoto, A.; Norinder, J.; Nakamura, E. Angew. Chem. Int. Ed. 2009, 48, 2925-2928.
Mechanistic Study of the Manganese-Catalyzed [2 + 2 + 2] Annulation of 1,3-Dicarbonyl Compounds and Terminal Alkynes
Yoshikai, N.; Zhang, S.-L.; Yamagata, K.-i.; Tsuji, H.; Nakamura, E. J. Am. Chem. Soc. 2009, 131, 4099-4109.
Theory of Organocopper-Mediated Reactions
Nakamura, E.; Yoshikai, N. In The Chemistry of Organocopper Compounds, Rappoport, Z.; Marek, I. Eds., Wiley, 2009.
Ligand Exchange as the First Irreversible Step in the Nickel-Catalyzed Cross-Coupling Reaction of Grignard Reagents
Yoshikai, N.; Matsuda, H.; Nakamura, E. J. Am. Chem. Soc. 2008, 130, 15258-15259.
Origin of the Regio- and Stereoselectivity of Allylic Substitution of Organocopper Reagents
Yoshikai, N.; Zhang, S.-L.; Nakamura, E. J. Am. Chem. Soc. 2008, 130, 12862-12863.
Iron-Catalyzed Direct Arylation through Directed C-H Bond Activation
Norinder, J.; Matsumoto, A.; Yoshikai, N.; Nakamura, E. J. Am. Chem. Soc. 2008, 130, 5858-5859.
Mechanism of Nucleophilic Substitution of Acyl Electrophiles using Lithium Organocuprates
Yoshikai, N.; Iida, R.; Nakamura, E. Adv. Synth. Catal. 2008, 350, 1063-1072.
Aminohydroxyphosphine Ligands for Copper-Catalyzed Enantioselective Conjugate Addition of Organozinc Reagents
Hajra, A.; Yoshikai, N.; Nakamura, E. Org. Lett. 2006, 8, 4153-4155.
Bimetallic Synergism in Alkyne Silylformylation Catalyzed by Cobalt-Rhodium Mixed-Metal Cluster
Yoshikai, N.; Yamanaka, M.; Ojima, I.; Morokuma, K.; Nakamura, E. Organometallics 2006, 25, 3867-3875.
Mechanism of Remote Conjugate Addition of a Lithium Organocuprate to Polyconjugated Carbonyl Compounds
Yoshikai, N.; Yamashita, T.; Nakamura, E. Chem. Asian. J. 2006, 1, 322-330.
Unusual Homo-Coupling in the Reaction of Diorganocuprates with an Allylic Halide
Norinder, J.; Bäckvall, J.-E.; Yoshikai, N.; Nakamura, E. Organometallics 2006, 25, 2129-2132.
Nickel-Catalyzed Cross-Coupling Reaction of Aryl Fluorides and Chlorides with Grignard Reagents under Nickel/Magnesium Bimetallic Cooperation
Yoshikai, N.; Mashima, H.; Nakamura, E. J. Am. Chem. Soc. 2005, 127, 17978-17979.
Mechanism of Remote Conjugate Addition of a Lithium Organocuprate to a Polyconjugated Carbonyl Compound
Yoshikai, N.; Yamashita, T.; Nakamura, E. Angew. Chem. Int. Ed. 2005, 44, 4721-4723.
Synergistic Dimetallic Effects in Propargylic Substitution Reaction Catalyzed by Thiolate-Bridged Diruthenium Complex
Ammal, S. C.; Yoshikai, N.; Inada, Y.; Nishibayashi, Y.; Nakamura, E. J. Am. Chem. Soc. 2005, 127, 9428-9438.
Enantioselective Allylic Substitution of Cinnamyl Esters Catalyzed by Iridium-Chiral Aryl Phosphite Complex: Conspicuous Change in the Mechanistic Spectrum by a Counter Cation and Solvent
Kinoshita, N.; Marx, K. H.; Tanaka, K.; Tsubaki, K.; Kawabata, T.; Yoshikai, N.; Nakamura, E. J. Org. Chem. 2004, 69, 7960-7964.
L-shaped Three-center Two-electron (C-C-C)+ Bonding Array
Yoshikai, N.; Ammal, S. C.; Nakamura, E. J. Am. Chem. Soc. 2004, 126, 12941-12948.
Mechanism of Substitution Reaction on sp2-Carbon Center with Lithium Organocuprate
Yoshikai, N.; Nakamura, E. J. Am. Chem. Soc. 2004, 126, 12264-12265.
On the Mechanism of “Higher-Order Cuprate”, Alias Lipshutz Cuprate
Nakamura, E.; Yoshikai, N. Bull. Chem. Soc. Jpn. 2004, 77, 1-12.
Theoretical Studies on Diastereo- and Enantioselective Rhodium-Catalyzed Cyclization of Diazo Compound via Intramolecular C-H Bond Insertion
Yoshikai, N.; Nakamura, E. Adv. Synth. Catal. 2003, 345, 1159-1171.
Mechanism of C-H Bond Activation/C-C Bond Formation Reaction between Diazo Compound and Alkane Catalyzed by Dirhodium Tetracarboxylate
Nakamura, E.; Yoshikai, N.; Yamanaka, M. J. Am. Chem. Soc. 2002, 124, 7181-7192.
Carbozincation of Dipolar Trimethylenemethane. A New Route to Functionalized Organozinc Reagents
Nakamura, M.; Yoshikai, N.; Nakamura, E. Chem. Lett. 2002, 146-147.
[3 + 3] Cycloaddition of Dipolar Trimethylenemethane with Active Methylene Compound
Nakamura, M.; Yoshikai, N.; Toganoh, M.; Nakamura, E. Synlett 2001, 1030-1033.
Kinetic Reactivity of “Higher Order Cuprate” in SN2 Alkylation Reaction
Nakamura, E.; Yamanaka, M.; Yoshikai, N.; Mori, S. Angew. Chem. Int. Ed. 2001, 40, 1935-1938.