研究成果/論文発表

研究成果

原著論文

新聞等掲載記事など

論文発表

2023年

原著論文
  1. Hiroyuki Yamakoshi, Michihiro Fukuda, Hiro Ikeda, Shogo Fujiki, Aki Kohyama, Shota Nagasawa, Hanae Shinozaki, Hiroyuki Shibata, Yoshiharu Iwabuchi, “Design, synthesis, and biological evaluation of water-soluble prodrugs of C5-curcuminoid GO-Y030 based on reversible thia-Michael reaction.” Chem. Pharm. Bull. accepted.
  2. Hiroyuki Yamakoshi, Daiki Shibata, Kazuki Bando, Shinji Kajimoto, Aki Kohyama, Syusuke Egoshi, Kosuke Dodo, Yoshiharu Iwabuchi, Mikiko Sodeoka, Katsumasa Fujita, Takakazu Nakabayashi “Ratiometric analysis of reversible thia-Michael reactions using nitrile-tagged molecules by Raman microscopy.” Chem. Commun. 59, 14563-14566 (2023). doi.10.1039/d3cc05015g
  3. Shogo Moriyama, Miyu Mae, Daiki Shibata, Hiroyuki Yamakoshi, Shinji Kajimoto, Takakazu Nakabayashi, Takayoshi Ishimoto, Kaiki Mogi, Hironao Sajiki, Shuji Akai, Yoshinari Sawama, “Multiple deuteration of triphenylphosphine and live-cell Raman imaging of deuterium-incorporated Mito-Q.” Chem. Commun. 59, 12100-12103 (2023). doi.10.1039/d3cc04410f
  4. Yahani P. Jayasinghe, Michael T. Banco, Jared J. Lindenberger, Lorenza Favrot, Zuzana Pal-ekova, Mary Jackson, Shino Manabe, Donald R. Ronning “The Mycobacterium tuberculosis mycothiol S-transferase is divalent metal-dependent for mycothiol binding and transfer”, RSC Med. Chem. RSC Med. Chem. 14, 491-500 (2023) . doi.org/10.1039/D2MD00401A
  5. Hiroki Takashima, Kazunobu Ohnuki, Shino Manabe, Yoshikatsu Koga, Ryo Tsumura, Takahiro Anzai, Yang Wang, Xiaojie Yin, Nozomi Sato, Yudai Shigekawa, Akihiro Nambu, Sachiko Usuda, Hiromitsu Haba, Hirofumi Fujii, Masahiro Yasunaga, “Tumor targeting of 211At-labeled antibody under sodium ascorbate protection against radiolysis” Mol. Pharm. 20(2), 1156-1167 (2023). doi.10.1021/acs.molpharmaceut.2c00869
  6. Methanee Hiranyakorn, Shogo Iwamoto, Asako Hoshinoo, Ryo Tsumura, Hiroki Takashima, Masahiro Yasunaga, and Shino Manabe “Chromatographic Analysis of N-glycan Profile on Therapeutic Anti-bodies using FcγRIIIa Affinity Column Chromatography” ACS Omega, 8(18), 16513-16518 (2023) doi.org/10.1021/acsomega.3c02374
  7. Masanori Shigeno, Akihisa Kajima, Eito Toyama, Toshinobu Korenaga, Hiroyuki Yamakoshi, Kanako Nozawa-Kumada, Yoshinori Kondo “LiHMDS-mediated deprotonative coupling of toluenes with ketone” Chem. Eur. J. 29, e202203549 (2023) https://doi.org/10.1002/chem.202203549
総説
  1. Hiroyuki Yamakoshi, Jun Ando, Shusuke Egoshi, Kosuke Dodo, Mikiko Sodeoka, Katsumasa Fujita Raman imaging and screening of bioactive small molecules Raman Spectroscopy in Human Health and Biomedicine 1st Edition; H. Sato, J. Popp, B. R. Wood, Y. Ozeki; World Scientific; 2023; pp 271-298.
  2. Takashi Maruyama, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Shibata ”Mono-carbonyl curcumin analogs for cancer therapy” Biol. Pharm. Bull. 46(6), 756-763 (2023) https://doi.org/10.1248/bpb.b23-00103
  3. Kazuchika Nishitsuji, Midori Ikezaki, Shino Manabe, Yoshito Ihara、西辻和親、池﨑みどり、眞鍋 史乃、井原 義人“Function of protein C-mannosylation in physiology and pathology” 「タンパク質C-マンノシル化の生理機能と病態における機能」Trends Glycosci. Glycotechnol. 35, E23-E27 (2023); 35, J23-J27 (2023). doi.org/10.4052/tigg.2218.1e; 10.4052/tigg.2218.1e
プロシーディングス
  1. Hiroki Takashima, Kazunobu Ohnuki, Shino Manabe, Yoshikatsu Koga, Ryo Tsumura, Takashiro, Anzai, Yang Wang, Xiaojie Yin, Nozomi Sato, Yudai Shigekawa, Akihiro Nambu, S. Usuda, Hiromitsu Haba, Hirofumi Fujii, Masahiro Yasunaga, “Prevention of radionuclide-induced antibody denaturation maintains active targeting and maximizes antitumor efficacy in 211At-radioimmunotherapy” RIKEN Accel. Prog. Rep. in press.
著書
  1. 眞鍋史乃「ピラノシド異性化反応:常識ではないグリコシド立体化学制御」ドラマチック有機化学感動の瞬間100、有機合成化学協会編、化学同人、134-135 (2023).

2022年

原著論文
  1. Kimihiro Noguchi, Sayuri Saito, Hiroyuki Yamakoshi, Seiichi Nakamura, “Stereoselective synthesis of the DE ring portion of kadcoccilactone A by a radical addition/cyclization approach” Eur. J. Org. Chem. e202201201 (2022) doi.org/10.1002/ejoc.202201201
  2. Kazunobu Ohnuki, Mitsuyoshi Yoshimoto, Hiromitsu Haba, Shino Manabe, Hiroki Takashima, Masahiro Yasunaga, Hirofumi Fujii, “Protection from contamination by 211At, an enigmatic but promising alpha emitter” EJNMMI Physics, 9, 39 (2022). doi.org/10.1186/s40658‐022‐00469‐9
  3. Kohyama, A.; Kim, M. J.; Yokoyama, R.; Sun, S.; Omar, A. M.; Phan, N. D.; Meselhy, M. R.; Tsuge, K.; Awale, S.; Matsuya, Y. “Structure-activity relationship and mechanistic study on gugglesterone derivatives; discovery of new anti-pancreatic cancer candidate”, Bioorg. Med. Chem. 54, 116563 (2022). doi.org/10.1016/j.bmc.2021.116563
  4. Masanori Shigeno, Kazuya Hanasaka, Itsuki Tohara, Koki Izumi, Hiroyuki Yamakoshi, Eunsang Kwon, Kanako Nozawa- Kumada, Yoshinori Kondo, “Direct C-H carboxylation forming polyfunctionalized aromatic carboxylic acids by combined Bronsted bases”, Org. Lett. 24(3), 809-814 (2022). doi:org/10.1021/acs.orglett.1c03866
  5. Kazuchika Nishitsuji, Midori Ikezaki, Shino Manabe, Kenji Uchimura, Yukishige Ito, Yoshito Ihara, “Thrombospondin type 1 repeat-derived C-mannosylated peptide attenuates synaptogenesis of cortical neurons induced by primary astrocytes via TGF-β”, Glycoconj. J. in press. doi: 10.1007/s10719-021-10030-y.
  6. Midori Ikezaki, Kazuchika Nishitsuji, Ko Matsumura, Shino Manabe, Yukinao Shibukawa, Yoshinao Wada, Yukishige Ito, Yoshito Ihara, “C-Mannosylated tryptophan-containing peptide binds 1 to actinin-4 and suppresses E2 cadherin-dependent cell-cell interactions in lung epithelial-like A549 cells”, Biochimie, in press. doi:10.1016/j.biochi.2021.10.007
総説
  1. 何 建海、山越 博幸、盛田 伸一「スペクトル解析によるバイオ・ラマンデータ化学種の成分分離に向けて」細胞, 54, 774-777 (2022).
  2. 眞鍋史乃、安永正浩「抗体薬物複合体 (ADC) の設計:breakthrough と課題」腫瘍内科、30, 436-441 (2022).
  3. 眞鍋史乃、「糖鎖連結抗体・薬物複合体作製による抗体機能増強」、実験医学増刷「新たな時代を迎えた抗体医薬」、津本浩平著、40 (20), 88-96 (3274-3282) (2022).
  4. 眞鍋史乃、「抗体―薬物複合体開発の発展と現状:ドラッグデリバリーシステムの改良による抗悪性腫瘍薬の効果増強」メディカルレビュ―、19, 12-15 (2022)
プロシーディングス
  1. Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Kazunobu Onuki, Ryo Tsumura, Takahiro Anzai, Nozomu Iwata, Masahiro Yasunaga, Yang Wang, Takuya Yokokita, Yukiko Komori, Daiki Mori, Hiromitsu Haba, Hirofumi Fujii, Yasuhiro Matsumura, “Sodium ascorbate protects 211At-labeled antibodies from reactive oxygen species damage” RIKEN Accel. Prog. Rep. 55, S25 (2022).
著書
  1. ラマン顕微鏡を用いた低分子化合物の生細胞解析
    山越 博幸、江越 脩祐、闐闐 孝介、袖岡 幹子、藤田 克昌
    技術情報協会 ラマン分光スペクトルデータ解析事例集 第11章 第4節 2022, 366-372.

2021年

原著論文
  1. Shino Manabe, Hiroki Takashima, Kazunobu Ohnuki, Yoshikatsu Koga, Ryo Tsumura, Nozomi Iwata, Yang Wang, Takuya Yokokita, Yukiko Komori, Sachiko Usuda, Daiki Mori, Hiromitsu Haba, Hirofumi Fujii, Masahiro Yasunaga, Yasuhiro Matsumura, “Stabilization of an 211At-labelled antibody with sodium ascorbate” ACS Omega, 6(23), 14887-14895 (2021) doi.org/10.1021/acsomega.1c00684
  2. Hiroki Takashima, Yoshikatsu Koga, Shino Manabe, Kazunobu Onuki, Ryo Tsumura, Takahiro Anzai, Nozomi Iwata, Yan Wang, Takuya Yokokita, Yukiko Komori, Daiki Mori, Hiromitsu Haba, Hirofumi Fujii, Yasuhiro Matsumura, Masahiro Yasunaga, “Radioimmunotherapy with an 211At-labeled anti-tissue factor antibody protected by sodium ascorbate” Cancer Sci. 112(5), 1975-1986 (2021) doi.org/10.1111/cas.14857
  3. Shuhei Morita, Yoko Inai, Shiho Minakata, Shohei Kishimoto, Shino Manabe, Naoyuki Iwahashi, Kazuhiko Ino, Yukishige Ito, Takashi Akamizu, Yoshito Ihara, “Quantification of serum C-mannosyl tryptophan by novel assay to evaluate renal function and vascular complications in patients with type 2 diabetes” Sci. Rep. 11, 1946 (2021) doi.org/10.1038/s41598-021-81479-y
  4. Ryo Tsumura, Takahiro Anzai, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masashiro Yasunaga, Yasuhiro Matsumura, “Antitumor effect of humanized anti-tissue factor antibody-drug conjugate in peritoneal disseminated pancreatic cancer model” Oncol. Rep. 45(1), 329-336 (2021) doi.10.3892/or.2020.7850
  5. Saki Inatomi, Yuta Takayanagi, Kento Watanabe, Akinori Toita, Hiroyuki Yamakoshi, Seiichi Nakamura, “Stereoselective 1,4-Addition of Primary Alcohols to γ-Alkoxy-α,β-unsaturated Esters” Synthesis 53(01), 161-174 (2021) doi.10.1055/s-0040-1707274
総説
  1. Shiho Minakata, Shino Manabe, Yoko Inai, Midori Ikezaki, Kazuchika Nishitsuji, Yukishige Ito, Yoshito Ihara, “Protein C-mannosylation and C-mannosyl tryptophan in chemical biology and medicine” Molecules, 26, 5258 (2021). doi.org/10.3390/molecules26175258
  2. 眞鍋史乃、「糖環開裂反応を用いたグリコシル化」第三の生命鎖「糖鎖」を構築する合成化学-グリコシル化の最前線-、月刊バイオインダストリー、38(8) 42-53 (2021)
  3. Shino Manabe, Yoshiki Yamaguchi “Antibody glycoengineering and homogeneous antibody-drug conjugate preparation” Chem. Rec. 21, 3005-3014 (2021). doi.org/10.1002/tcr.202100054
  4. Shino Manabe, “Recent development of stereoselective glycosylation reactions” Heterocycles, 102(2) 177-201 (2021) doi.org/10.3987/REV-20-933
  5. 眞鍋史乃、「日本アカデミアでの有機合成からのアプローチ」、BIO Clinica 「ADC (抗体薬物複合体) 薬の進歩」, 36 (6) (403-407) 11-15 (2021)
  6. 眞鍋史乃、廣瀬賢治、「抗体―薬物複合体(ADC)に活用された化学」、Drug Delivery Syst. 36(1) 296-307 (2021) doi.org/10.2745/dds.36.28
  7. 山越博幸、「新規骨格構築法を基盤とする縮環生物活性天然物の合成研究」、薬学雑誌、141(9), 1087-1094 (2021) doi:org/10.1248/yakushi.21-00126(2020 年度日本薬学会東海支部学術奨励賞受賞論文)
プロシーディングス
  1. Hiroki Takashima, Yoshikatsu Koga, K. Onuki, Shino Manabe, Ryo Tsumura T. Anzai, N. Iwata, Masahiro Yasunaga, W. Yang, T. Yokokita, Yukiko Komori, Daiki Mori, Hitomitsu Haba, Hirofumi Fujii, Yasuhiro Matsumura “Development of radioimmunotherapy with astatine-211-counjugated antibodies” RIKEN Accel. Prog. Rep. in press.
  2. 眞鍋史乃、「211At化学種と抗体付加反応」、大阪大学放射線科学基盤機構フロンティア放射線科学フロンティア~孟宗竹~、2021, 13
  3. 眞鍋史乃、「生命機能解明を志向した複合糖質有機合成化学」、星薬科大学紀要、62, 59-66 (2021)
著書
  1. Hiroyuki Yamakoshi, Katsumasa Fujita, “Spontaneous Raman and SERS microscopy for Raman tag imaging”, in “Stimulated Raman scattering microscopy techniques and applications”, 1st Edition; J.-X. Cheng, W. Min, Y. Ozeki, D. Polli; Elsevier; pp 275?287 (2021).
  2. Yoshito Ihara, Shino Manabe, Yoko Inai, Yukishige Ito, “C-Mannosyl tryptophan: from chemistry to biology” in “Comprehensive Glycoscience, IV Second Edition“ Johannis P. Karmerling, Gert. J. Boons, Yuan Chan Lee, Akemi Suzuki, Naoyuki Taniguchi, A. G. J. Voragen eds. Elsevier, 162-182 (2021)
  3. 眞鍋史乃、安永正浩「抗体―薬物複合体」「創薬研究者・アカデミア研究者が知っておくべき 最新の免疫学とその応用技術」佐藤章広編、技術情報協会、in press (2021)

2020年

原著論文
  1. Shiho Minakata, Yoko Inai, Shino Manabe, Kazuchika Nishitsuji, Yukishige Ito, Yoshito Ihara, “Monomeric C-mannosyl tryptophan is a degradation product of autophagy in cultured cells” Glycoconj. J. 37(5), 635-645 (2020) doi.10.1007/s10719-020-09938-8
  2. Naoyuki Iwahashi, Yoko Inai, Shiho Minakata, Sho Sakurai, Shino Manabe, Yukishige Ito, Kazuhiko Ino, Yoshito Ihara, “C-Mannosyl tryptophan increases in the plasma of ovarian cancer” Oncol. Lett. 19(1), 908-919 (2020) doi.10.3892/ol.2019.11161
  3. Kota Koike, Kazuki Bando, Jun Ando, Hiroyuki Yamakoshi, Naoki Terayama, Kosuke Dodo, Nicholas Isaac Smith, Mikiko Sodeoka, and Katsumasa Fujita, “Quantitative Drug Dynamics Visualized by Alkyne-Tagged Plasmonic-Enhanced Raman microscopy” ACS Nano 14(11), 15032-15041 (2020) doi.org/10.1021/acsnano.0c05010
総説
  1. Shino Manabe, “Glycan-conjugated homogeneous antibody-drug conjugate synthesis” Translate. Regulat. Sci. 2(3), 84-89 (2020) doi.org/10.33611/trs.2020_012
  2. 眞鍋史乃、DDS の「ちょっとした」技術・知識 順相TLC Drug Delivery Syst. 35(2) 147-179 (2020) doi.org/10.2745/dds.35.147
  3. 眞鍋史乃、山口芳樹、松村保広、「有機合成化学/糖鎖化学は抗体―薬物複合体開発にどのように貢献できるか」、有機合成化学協会誌、78(5) 485-494 (2020) doi.org/10.5059/yukigoseikyokaishi.78.485
著書
  1. Shino Manabe, “Recent progress in linker technology for antibody-drug conjugates: Methods for connection and release” in “Cancer Drug Delivery Systems based on the Tumor Microenvironment”, Yasuhiro Matsumura and David Tarin eds. Springer Japan, 93-123 (2020)
  2. Masahiro Yasunaga, Shino Manabe, Yasuhiro Matsumura, “CAST Therapy” in “Cancer Drug Delivery Systems based on the Tumor Microenvironment”, Yasuhiro Matsumura and David Tarin eds. Springer Japan, 269-288 (2020)

2019年以前

原著論文
  1. Skye Travis, Madeline R. Shay, Shino Manabe, Nathaniel C. Gilbert, Patrick Frantom, Matthew K. Thompson, “Characterization of the genomically encoded Fosfomycin resistance enzyme from Mycobacterium abscessus” Med. Chem. Commun. 10(11), 1948-1957 (2019) doi.10.1039/c9md00372j
  2. Ryo Tsumura, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura, “Evaluation of the antitumor mechanism of antibody-drug conjugates against tissue factor in stroma rich allograft models” Cancer Sci. 110(10), 3296-3305 (2019) doi.10.1111/cas.14146
  3. Shino Manabe, Yukishige Ito, "1,2-cis-selective formation of a unique amino-containing amino glycoside by endocyclic cleavage strategy" Heterocycles, 99(2), 1304-1314 (2019) doi.10.3987/COM-18-S(F)101
  4. Shino Manabe, Yoshiki Yamaguchi, Kana Matsumoto, Hirobumi Fuchigami, Taiji Kawase, Kenji Hirose, Ai Mitani, Wataru Sumiyoshi, Takashi Kinoshita, Junpei Abe, Masahiro Yasunaga, Yasuhiro Matsumura, Yukishige Ito, “Characterization of antibody products obtained through enzymatic and non-enzymatic glycosylation reactions with a glycan oxazoline and preparation of homogeneous antibody-drug conjugate via Fc N-glycan” Bioconj. Chem. 30(5), 1343-1355 (2019) doi.10.1021/acs.bioconjchem.9b00132
  5. Sho Sakurai, Yoko Inai, Shiho Minakata, Shino Manabe, Yukishige Ito, Yoshito Ihara, “A novel assay for detection and quantification of C-mannosyl tryptophan in normal or diabetic mice” Sci. Rep. 9(1), 4675 (2019) doi.10.1038/s41598-019-41278-y
  6. Hirobumi Fuchigami, Shino Manabe, Masahiro Yasunaga, Yasuhiro Matsumura, "Chemotherapy payload of anti-insoluble fibrin antibody-drug conjugate is released specifically upon binding to fibrin" Sci. Rep. 8(1), 14211 (2018) doi.10.1038/s41598-018-32601-0
  7. Ryo Tsumura, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura, "Influence of the dissociation rate constant on the intra-tumor distribution of antibody-drug conjugate against tissue factor" J. Control. Release, 284, 49-56 (2018) doi.10.1016/j.jconrel.2018.06.016
  8. Shino Manabe, Junpei Abe, Yukishige Ito, "Amide bond formation of sialic acid in oligosaccharide without protecting group" Heterocycles, 97(2), 1203-1209 (2018) doi. 10.3987/COM-18-S(T)69
  9. Shino Manabe, Yukishige Ito, "Comparing of endocyclic and exocyclic cleavage reactions using mycothiol synthesis as an example" Tetrahedron, 74(20), 2440-2446 (2018) doi.org/10.1016/j.tet.2018.03.069
  10. Shino Manabe, Yoshiki Yamaguchi, Junpei Abe, Kana Matsumoto, Yukishige Ito, "Acceptor range of endo-β-N-acetylglucosaminidase mutant endo-CC N180H: from monosaccharide to antibody" R. Soc. Open Sci. 5(5), 171521 (2018) doi.10.1098/rsos.171521
  11. Tanim J. Hossain, Shino Manabe, Yukishige Ito, Toshiya Iida, Saori Kosono, Kenji Ueda, Akira Hosomi, Daishi Inoue, Tadashi Suzuki, "Enrichment and characterization of a bacterial mixture capable of utilizing C-mannosyl tryptophan as a carbon source" Glycoconj. J. 35(2), 165-176 (2018) doi.10.1007/s10719-017-9807-2
  12. Masahiro Yasuanga, Shino Manabe, Yasuhiro Matsumura, “Immunoregulation by IL-7R-targeting antibody-drug conjugates: Overcoming steroid-resistance in cancer and autoimmune disease” Sci. Rep. 7(1), 10735 (2017) doi.10.1038/s41598-017-11255-4
  13. Yuki Fujiwara, Masaru Furuta, Shino Manabe, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura, “Imaging mass spectrometry for the exquisite design of antibody-drug conjugates” Sci. Rep. 6, 24954 (2016) doi. 10.1038/srep24954
  14. Shino Manabe, Yukishige Ito, “Mycothiol synthesis by anomerization reaction via endocyclic cleavage” Beilstein J. Org. Chem. 12, 328-333 (2016) doi. 10.3762/bjoc.12.35
  15. Yoshikatsu Koga, Shino Manabe, Yoshiyuki Aihara, Ryota Sato, Ryo Tsumura, Hikaru Iwafuji, Fumiaki Furuya, Hirobumi Fuchigami, Yuki Fujiwara, Yohei Hisada, Yoshiyuki Yamamoto, Masahiro Yasunaga, Yasuhiro Matsumura, “Antitumor effect of anti-tissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts” Int. J. Cancer, 137(6), 1457-1466 (2015) doi. 10.1002/ijc.29492
  16. Shino Manabe, Hiroko Satoh, Jurg Hutter, Hans Peter Luthi, Teodoro Laino, Yukishige Ito, “Significant substituent effect on the anomerization of pyranosides: Mechanism of anomerization and synthesis of a 1,2-cis glucosamine oligomer from the 1,2-trans anomer” Chem. Eur. J. 20(1), 124-132 (2014) (Selected in ChemistryViews) doi.10.1002/chem.201303474
  17. Shino Manabe, Yukishige Ito, “Hafnium(IV) tetratriflate in selective reductive carbohydrate benzylidene acetal opening reaction and direct silylation reaction” Tetrahedron Lett. 54(50), 6838-6840 (2013) doi.org/10.1016/j.tetlet.2013.10.011
  18. Yohei Hisada, Masahiro Yasunaga, Shingo Hanaoka, Shinji Saijou, Takashi Sugino, Atsushi Tsuji, Tsuneo Saga, Kohei Tsumoto, Shino Manabe, Jun-ichiro Kuroda, Jun-ichi Kuratsu, Yasuhiro Matsumura, “Discovery of an unexplored space in fibrin clots and its clinical significance” Sci. Rep. 3, 2604 (2013) doi.10.1038/srep02604
  19. Shino Manabe, Masanori Yamaguchi, Yukishige Ito, “Sulfonylcarbamate as a versatile and unique hydroxy-protecting group: Protecting group stable under severe conditions and labile under mild conditions” Chem. Commum. 49(75), 8332-8334 (2013) doi.10.1039/c3cc43968b
  20. Shino Manabe, Yuksihige Ito, “Hafnium(IV) tetratriflate as a glycosyl fluoride activation reagent” J. Org. Chem. 78(9), 4568-4572 (2013) doi.10.1021/jo400282x
  21. Shino Manabe, Hikaru Machida, Yoshiyuki Aihara, Masahiro Yasunaga, Yukishige Ito, Yasuhiro Matsumura, “Development of diketopiperazine-forming dipeptidyl Pro-Gly spacer for preparation of antibody-drug conjugate” Med. Chem. Commun. 4(5), 792-796 (2013) (Most downloaded articles for 30 days) doi.10.1039/C3MD00075C
  22. Masahiro Yasunaga, Shino Manabe, David Tarin, Yasuhiro Matsumura, “Tailored immunoconjugate therapy depending on a quantity of tumor stroma” Cancer Sci. 104(2), 231-237 (2013) doi.10.1111/cas.12062
  23. Toshiki Nokami, Akito Shibuya, Yoshihiro Saigusa, Shino Manabe, Yukishige Ito, Jun-ichi Yoshida, “Electrochemical generation of 2,3-oxazolidinone glycosyl triflates as an intermediate for stereoselective glycosylation“ Beilstein J. Org. Chem. 8, 456-460 (2012) doi.10.3762/bjoc.8.52
  24. Shino Manabe, Kazuyuki Ishii, Hiroko Satoh, Yukishige Ito, “Substituent effect in endocyclic cleavage-recyclization anomerization reaction of pyranosides” Tetrahedron, 67(51), 9966-9974 (2011) doi.org/10.1016/j.tet.2011.09.059
  25. Shino Manabe, Yoshiyuki Aihara, Yukishige Ito, “Radical C-glycosylation reaction of pyranosides with 2,3-trans carbamate group” Chem. Commun. 47(34), 9720-9722 (2011) doi.10.1039/c1cc13172a
  26. Masahiro Yasunaga, Shino Manabe, David Tarin, Yasuhiro Matsumura, “Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue” Bioconj. Chem. 22(9), 1776-1783 (2011) doi.10.1021/bc200158j
  27. Masahiro Yasunaga, Shino Manabe, Yasuhiro Matsumura, “New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots” Cancer Sci. 102(7), 1396-1402 (2011) (selected paper) doi.10.1111/j.1349-7006.2011.01954.x
  28. Hiroko Satoh, Shino Manabe, Yukishige Ito, Hans P. Luthi, Teodoro Laino, Jurg Hutter, “Endocyclic cleavage in glycosides with 2,3-trans cyclic protecting groups” J. Am. Chem. Soc. 133(14), 5610-5619 (2011) doi.10.1021/ja201024a
  29. Toshiki Nokami, Yuki Nozaki, Yoshihiro Saigusa, Akito Shibuya, Shino Manabe, Yukishige Ito, Jun-ichi Yoshida, "Glycosyl sulfonium ions as storable intermediates for glycosylations” Org. Lett. 13(6), 1544-1547 (2011) doi.10.1021/ol200242u
  30. Shino Manabe, Kazuyuki Ishii, Yukishige Ito, “N-Benzyl 2,3-trans carbamates bearing glycosyl donors for 1,2-cis selective glycosylation reactions” Eur. J. Org. Chem. (3), 497-516 (2011) doi.org/10.1002/ejoc.201001278
  31. Yoshito Ihara, Shino Manabe, Midori Ikezaki, Yoko Inai, In-Sook Lee Matsui, Yuriko Ohta, Eiji Muroi, Yukishige Ito, “C-Mannosylated peptides derived from the thrombospondin type 1 repeat interact with Hsc70 to modulate its signaling in RAW264.7 cells” Glycobiology, 20(10), 1298-1310 (2010) doi.10.1093/glycob/cwq096
  32. Hiroko Satoh, Halbor S. Hansen, Shino Manabe, Wilfred F. van Gunsteren, Philippe H. Hunenberger, “Theoretical investigation of solvent effects on glycosylation reactions: Stereoselectivity controlled by preferential conformations of the intermediate oxacarbenium-counterion complex” J. Chem. Theory Comput. 6(6), 1783-1797 (2010) doi.10.1021/ct1001347
  33. Shino Manabe, Yukishige Ito, “Significant solvent effect in anomerization reaction of pyranosides” Tetrahedron Lett. 50(34), 4827-4829 (2009) doi.org/10.1016/j.tetlet.2009.05.119
  34. Shino Manabe, Kazuyuki Ishii, Daisuke Hashizume, Hiroyuki Koshino, Yukishige Ito, “Evidence for endocyclic cleavage of conformationally restricted glycopyranosides” Chem. Eur. J. 15(28), 6894-6901 (2009) doi.10.1002/chem.200900064
  35. Toshiki Nokami, Akito Shibuya, Shino Manabe, Yukishige Ito, Jun-ichi Yoshida, “α- and β-Glycosyl sulfonium ions; Generation and reactivity" Chem. Eur. J. 15(10), 2252-2255 (2009) doi.10.1002/chem.200802293
  36. Hiroko Satoh, Jurg Hutter, Hans-Peter Luthi, Shino Manabe, Kazuyuki Ishii, Yukishige Ito, “Low barrier pathway for endo-cleavage induced anomerization of pyranosides with N-benzyl-2,3-trans oxazolidinone” Eur. J. Org. Chem. (8), 1127-1131 (2009) doi.10.1002/ejoc.200801140
  37. Shino Manabe, Kazuyuki Ishii, Daisuke Hashizume, Yukishige Ito, "Phenyl N-benzyl-2-amino-6-O-benzyl 2,3-N, O-carbonyl-2-deoxy 1-thia-β-D-glycoside" Acta Crysta, Sect E. 64(10), o1868 (2008) doi.10.1107/S1600536808027189
  38. Shino Manabe, Akiharu Ueki, Yukishige Ito, “Reductive deprotection of propargyl ether by a SmI2-amine-water system and its application to polymer-supported oligosaccharide synthesis” Tetrahedron Lett. 49(35), 5159-5161 (2008) doi.org/10.1002/ejoc.200801140
  39. Shino Manabe, Yukishige Ito, "The first synthesis of N-Man-Trp; Alternative mannosylation modification of protein" SYNLETT (6), 880-882 (2008) doi.10.1055/s-2008-1032099
  40. Eiji Muroi, Shino Manabe, Midori Ikezaki, Yoshishige Urata, Shinichi Sato, Tadahito Kondo, Yukishige Ito, Yoshito Ihara, "C-Mannosylated peptides derived from the thrombospondin type I repeat enhance lipopolysaccharide-induced signaling in macrophage-like RAW 264.7 cells" Glycobiology 17(9), 1015-1028 (2007) doi.10.1093/glycob/cwm071
  41. Shino Manabe, Kazuyuki Ishii, Yukishige Ito, "The synthesis of a natural oligosaccharide antibiotic Helicobacter pylori" J. Org. Chem. 72(16), 6107-6115 (2007) doi.10.1021/jo070669p
  42. Shino Manabe, Akiharu Ueki, Yukishige Ito, "Polymer-supported oligosaccharide synthesis using ultrafiltration methodology" Chem. Commun. (35), 3673-3675 (2007) doi.10.1039/b705324j
  43. Shino Manabe, Kazuyuki Ishii, Daisuke Hashizume, Yukishige Ito, "S-Phenyl 2,3-O carbonyl 4,6-O-benzylidene 1-thio-α-D-mannopyranoside" Acta Crysta, Sect E. 63(6), o3028 (2007) doi.org/10.1107/S1600536807022210
  44. Shino Manabe, Tomoyuki Sugioka, Yukishige Ito, “Facile peptide thioester synthesis via solution-phase tosylamide preparation” Tetrahedron Lett. 48(5), 849-853 (2007) doi.org/10.1016/j.tetlet.2006.11.143
  45. Shino Manabe, Tomoyuki Sugioka, Yukishige Ito, “Facile preparation of N-acylsulfonamides by using sulfonyl isocyanate” Tetrahedron Lett. 48(5), 787-789 (2007) doi.org/10.1016/j.tetlet.2006.11.158
  46. Shino Manabe, Kazuyuki Ishii, Yukishige Ito, “N-benzyl-2,3-oxazolidinone as a glycosyl donor for selective α-glycosylation and one-pot oligosaccharide synthesis involving 1,2-cis-glycosylation” J. Am. Chem. Soc. 128(33), 10666-10667 (2006) doi.10.1021/ja062531e
  47. Shinya Hanashima, Kei-ichiro Inamori, Shino Manabe, Naoyuki Taniguchi, Yukishige Ito, “Systematic synthesis of bisubstrate-type inhibitors of N-acetylglucosaminyltransferases” Chem. Eur. J. 12(13), 3449-3462 (2006) doi.10.1002/chem.200501348
  48. Yoshito Ihara, Shino Manabe, Munetake Kanda, Hiroaki Kawano, Toshiaki Nakayama, Ichiro Sekine, Takahito Kondo, Yushikige Ito, “Increased expression of protein C-mannosylation in the aortic vessels of diabetic zucker rats” Glycobiology, 15(4), 383-392 (2005) doi.10.1093/glycob/cwi012
  49. Shinya Hanashima, Shino Manabe, Yukishige Ito, "Divergent syntheses of sialylated glycan chains: Combined use of polymer support, resin capture-release and chemo-enzymatic strategies" Angew. Chem. Int. Ed. 44(27), 4218-4224 (2005) doi.10.1002/anie.200500777
  50. Shinya Hanashima, Shino Manabe, Kei-ichiro Inamori, Naoyuki Taniguchi, Yukishige Ito, "Synthesis of bisubstrate type inhibitor of N-acetylglucosaminyltransferases using polymer-resin hybrid strategy" Angew. Chem. Int. Ed. 43(42), 5674-5677 (2004) doi.10.1002/anie.200460388
  51. Ichiro Matsuo, Megumi Wada, Shino Manabe, Yoshiki Yamaguchi, Keisuke Ohtake, Koichi Kato, Yukishige Ito, “Synthesis of monoglucosylated high-mannose type dodecasaccharide, a putative ligand for molecular chaperon, calnexin and calreticurin” J. Am. Chem. Soc. 125(12), 3402-3403 (2003) doi.10.1021/ja021288q
  52. Shinya Hanashima, Shino Manabe, Yukishige Ito, “Polymer-resin hybrid capture-release strategy for the rapid oligosaccharide construction” SYNLETT (7), 979-982 (2003) doi.10.1055/s-2003-39312
  53. Shino Manabe, Yoshihiko Marui, Yukishige Ito, “Total synthesis of mannosyl tryptophan and its derivatives” Chem. Eur. J. 9(6), 1435-1447 (2003) doi.10.1002/chem.200390163
  54. Shino Manabe, Yukishige Ito, “On resin real-time reaction monitoring of oligosaccharide solid-phase synthesis” J. Am. Chem. Soc. 124(43), 12638-12639 (2002) doi.10.1021/ja020781z
  55. Shino Manabe, Kimitoshi Sakamoto, Yoshiaki Nakahara, Masahiko Sisido, Takahiro Hohsaka, Yukishige Ito, “Preparation of glycosylated amino acid derivatives for glycoprotein synthesis by in vitro translation system” Bioorg. Med. Chem. 10(3), 573-582 (2002) doi.10.1016/s0968-0896(01)00304-2
  56. Hiromune Ando, Shino Manabe, Yoshiaki Nakahara, Yukishige Ito, “Solid-phase capture-release strategy applied in soluble polymer support oligosaccharide synthesis” Angew. Chem. Int. Ed. 40(24), 4725-4728 (2001) doi.org/10.1002/1521-3773(20011217)40:24<4725::AID-ANIE4725>3.0.CO;2-9
  57. Hiromune Ando, Shino Manabe, Yoshiaki Nakahara, Yukishige Ito, “Tag-reporter strategy for facile oligosaccharide synthesis on polymer support” J. Am. Chem. Soc. 123(16), 3848-3849 (2001) doi.org/10.1021/ja003856c
  58. Shino Manabe, Yukishige Ito, “Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis; Polymer supported glycosyl donor” Chem. Pharm. Bull. 49(9), 1234-1235 (2001) doi.org/10.1248/cpb.49.1234
  59. Maki Takatani, Toshihiro Nakama, Kazusuke Kubo, Shino Manabe, Yuko Nakahara, Yukishige Ito, Yoshiaki Nakahara, “Synthesis of N-linked pentasaccharides with isomeric glycosidic linkage” Glycoconj. J. 17(6), 361-375 (2000) doi.10.1023/A:1007151913476
  60. Shino Manabe, Yoshiaki Nakahara, Yukishige Ito, “Novel nitro Wang type linker for polymer support oligosaccharide synthesis; Polymer supported acceptor” SYNLETT (9), 1241-1244 (2000) doi.10.1023/A:1007151913476
  61. Shino Manabe, Yukishige Ito, “Total synthesis of novel subclass of glyco-amino acid; C2-α-D-C-Mannosylpyranosyl-L-tryptophan” J. Am. Chem. Soc. 121(41), 9754-9755 (1999). (Correction) J. Am. Chem. Soc. 122(21), 5232 (2000) doi:10.1021/ja004648n
  62. Shino Manabe, Yukishige Ito, Tomoya Ogawa, “Toward synthesis of novel C-glycoprotein from human RNase; Unexpected stereochemistry of epoxide opening by organolithium reagents in the presence of Lewis acid” Chem Lett. (9), 919-920 (1998) doi.org/10.1246/cl.1998.919
  63. Shino Manabe, Yukishige Ito, Tomoya Ogawa, “Solvent effect in glycosylation reactions on polymer support” SYNLETT, (6), 628-630 (1998) doi.10.1055/s-1998-1750
  64. Kiyoshi Tomioka, Manabu Okuda, Katumi Nishimura, Shino Manabe, Motomu Kanai, Yasuo Nagaoka, Kenji Koga, “Structural requirements of a chiral ligand for the catalytic asymmetric addition of thiophenol to α,β-unsaturated esters” Tetrahedron Lett. 39(15), 2141-2144 (1998) doi.org/10.1016/S0040-4039(98)00080-X
  65. Shino Manabe, Yukishige Ito, Tomoya Ogawa, “Multi-component carbohydrate coupling strategy on polymer support” Molecules on Line, 2(1), 40-45 (1998)
  66. Shino Manabe, “Enantioselective [2,3] sigmatropic rearrangement of α-propargyoxyacetic acids mediated by BuLi-(-)-sparteine complex” Chem. Pharm. Bull. 46(2), 335-336 (1998) doi.org/10.1021/ja962163m
  67. Shino Manabe, “The enantioselective [2,3] sigmatropic rearrangement mediated by a butyllithium-chiral ligand complex” Chem. Commun. (8), 737-738 (1997) doi.org/10.1039/A700906B
  68. Shino Manabe, “Aza-[2,3] sigmatropic rearrangement of phosphoramides” Tetrahedron Lett. 38(14), 2491-2492 (1997) doi.org/10.1016/S0040-4039(97)00374-2
  69. Gilbert Stork, Fred West, Hee Yoon Lee, Richard C. A. Isaccs, Shino Manabe, “The total synthesis of a natural cardenolide: (+) Digitoxigenin” J. Am. Chem. Soc. 118(43), 10660-10661 (1996) doi.org/10.1021/ja962163m
総説
  1. 眞鍋史乃、山口芳樹、「ADC 開発におけるリンカー設計の意義」、メディカルレビュー、17(2) 11-15 (2019)
  2. 眞鍋史乃、山口芳樹、「糖鎖改変による抗体―薬物複合体合成」、「糖鎖科学の最前線-合成から医薬への応用まで」-月刊ファインケミカル、48(11), 51-59 (2019)
  3. 眞鍋史乃、「抗体-薬物複合体の開発の現状」、Drug Delivery Syst. 34(1), 10-21 (2019)
  4. Masahiro Yasunaga, Shino Manabe, Atsushi Tsuji, Masaru Furuta, Koretsugu Ogata, Yoshikatsu Koga, Tsuneo Saga, Yasuhiro Matsumura, "Mass spectrometry imaging for early drug discovery and development" AIMS Medical Science, 5(2), 162-180 (2018) doi 10.3934/medsci.2018.2.162
  5. 眞鍋史乃、安永正浩、松村保広、「ADCにおけるリンカーの安定性向上・位置選択的結合」、PHARM STAGE, 18(1), 46-52 (2018)
  6. Masahiro Yasunaga, Shino Manabe, Atsushi Tsuji, Masaru Fujita, Koretsugu Ogata, Yoshikatsu Koga, Tsuneo Saga, Yasuhiro Matsumura, “Development of antibody-drug conjugates using DDS and molecular imaging" Bioengineering, 4(3), 78-90 (2017) doi.10.3390/bioengineering4030078
  7. Shino Manabe, Yukishige Ito, “Synthetic utility of endocyclic cleavage reaction” Pure Appl. Chem. 89(7), 899-910 (2017) doi.org/10.1515/pac-2016-0917
  8. 安永正浩、眞鍋史乃、辻厚至、古田大、緒方是嗣、古賀宣勝、藤原悠起、佐賀恒夫、松村保広、「抗体薬物複合体の研究開発における分子イメージングの有用性」、PHARM STAGE, 17(6), 42-48 (2017)
  9. 安永正浩、眞鍋史乃、辻厚至、古田大、緒方是嗣、古賀宣勝、藤原悠起、佐賀恒夫、松村保広、「分子イメージングを駆使したADCの開発」、薬学雑誌、137(5), 535-544 (2017) doi.org/10.1248/yakushi.16-00255-3
  10. 眞鍋史乃、「抗体-薬物複合体 要素技術と総合技術」、薬学雑誌、137(5), 523-524 (2017) doi.org/10.1248/yakushi.16-00255-F
  11. 安永正浩、眞鍋史乃、松村保広、「抗体DDS」BIO Clinica, 30(7), (651) 41- (656) 46 (2015)
  12. 眞鍋史乃、横山昌幸、「クロスリンカー」Drug Delivery Syst. 30(3), 247-250 (2015) doi.10.2745/dds.30.247
  13. Shino Manabe, Yukishige Ito, “Pyranosides with 2,3-trans carbamate groups: Exocyclic or endocyclic cleavage reaction?” Chem. Rec. 14(3), 502-515 (2014) doi.org/10.1002/tcr.201402004
  14. 安永正浩、眞鍋史乃、松村保広、「間質を標的とした治療法、開発と展望」がんと間質、病理と臨床、32(1), 57-63 (2014)
  15. Masahiro Yasunaga, Shino Manabe, Yasuhiro Matsumura, “Tumor stromal barrier and cancer stromal targeting therapy” Microvas. Rev. Commun. 6(1), 2-8 (2013)
  16. Hiroko Satoh, Shino Manabe, “Design of chemical glycosyl donors: does changing ring conformation influence selectivity/reactivity?” Chem. Soc. Rev. 42(10), 4297-4309 (2013) doi.org/10.14532/mvrc.6.2
  17. 眞鍋史乃、「抗体-抗がん剤複合体におけるリンカーテクノロジー」Drug Delivery Syst. 28(5), 406-411 (2013) doi.org/10.2745/dds.28.406
  18. 安永正浩、眞鍋史乃、「間質デリバリー」安永正浩、眞鍋史乃、松村保広、Drug Delivery Syst. 28(5), 396-405 (2013) doi.org/10.2745/dds.28.396
  19. 眞鍋史乃、佐藤寛子、「2,3-transカーバメート基を持つ糖構造の特異な反応性:糖化学におけるエンド開裂反応の再発見」有機合成化学協会誌、 71(6), 616-624 (2013) doi.org/10.5059/yukigoseikyokaishi.71.616
  20. Kazuyuki Ishii, Shino Manabe, “Synthesis of the immunostimulatory adjuvant QS-21 and an approach to elucidating its mechanism of action” Trends Glycosci. Glycotechnol. 24(140), 277-279 (2012) doi.org/10.4052/tigg.24.277
  21. 眞鍋史乃、「2,3-transカーバメート基を持つ糖構造の特異な反応性と糖鎖合成における有用性」応用糖質科学、2(4), 213-233 (2012
  22. 眞鍋史乃、安永正浩、松村保広、「抗間質抗体修飾による固形がん克服へのアプローチ」実験医学増刊「疾患克服を目指した最新ケミカルバイオロジー」30, 142-149 (1160-1167) (2012)
  23. 眞鍋史乃、井原義人、伊藤幸成、「新規タンパク質糖付加修飾、化学合成からの生物学への貢献」化学と生物、49(5), 301-305 (2011) doi.org/10.1271/kagakutoseibutsu.49.347
  24. 眞鍋史乃、「二糖類・多糖類の化学合成」化学と教育、57(6), 294-295 (2009).
  25. Shino Manabe, Yukishige Ito, “Optimizing glycosylation reaction selectivities by protecting group manipulation" Curr. Bioactive. Com. 4(4), 258-281 (2008) doi.10.2174/157340708786847861
  26. Shino Manabe, Kazuyuki Ishii, Yukishige Ito, “Development of novel glycosyl donors for 1,2-cis glycosylation reaction for amino sugar and synthesis of anti-Helicobacter pylori oligosaccharide” Trends Glycosci. Glycotechnol. 20(114), 187-202 (2008) doi.org/10.4052/tigg.20.187
  27. Shino Manabe, Tomoyuki Sugioka, Yukishige Ito, "Synthesis of peptide thioesters compatible with solid-phase Fmoc methodology” Peptide Sci. 117-118 (2006)
  28. 眞鍋史乃、「糖鎖を迅速に合成する」日本化学会生命化学研究レター、(16), 14-21 (2005)
  29. 眞鍋史乃、「糖鎖固相合成における固相上での反応進行モニタリングの開発」薬学研究の進歩、20, 70-85 (2004)
  30. 眞鍋史乃、「糖鎖固相合成のルネッサンス」化学工業、54(10), 797-803 (2003)
  31. Shino Manabe, Yukishige Ito, "The novel glycoprotein structure; C-Mannosyl tryptophan" Trends Glycosci. Glycotechnol. 15(84), 181-196 (2003) doi.10.4052/tigg.15.181
  32. 眞鍋史乃、伊藤幸成、「グリコシル化」ファルマシア、39(7), 680-681 (2003)
  33. 眞鍋史乃、伊藤幸成、「糖鎖固相合成における新手法の開発」ファルマシア、37(10), 884-888 (2001)
  34. Yukishige Ito, Shino Manabe, “Tag-reporter and resin capture-release strategy in oligosaccharide synthesis” Chem. Eur. J. 8(14), 3076-3084 (2002) doi.org/10.1002/1521-3765(20020715)8:14<3076::AID-CHEM3076>3.0.CO;2-N
  35. 眞鍋史乃、「糖鎖迅速合成への挑戦」化学と工業、55(2), 145-148 (2002)
  36. 伊藤幸成、眞鍋史乃、「糖鎖合成における新しい迅速合成法の開発」有機合成化学協会誌、60(5), 472-477 (2002) doi.org/10.5059/yukigoseikyokaishi.60.476
  37. 眞鍋史乃、「新規な複合糖質糖鎖迅速合成法の開発」薬学雑誌、122(5), 295-307 (2002) doi.org/10.1248/yakushi.122.295
  38. 眞鍋史乃、「糖鎖の固相合成、糖鎖合成の迅速化を目指して」伊藤幸成、高分子、47(10), 766-771 (1998)
  39. Yukishige Ito, Shino Manabe, “Solid-phase oligosaccharide synthesis and related technologies” Curr. Opin. Chem. Biol. 2(6), 701-708 (1998) doi.10.1016/s1367-5931(98)80106-3
著書
  1. Shino Manabe, "Antibody-drug conjugates (ADCs)" in "Glycoscience Application and Basic Science: Insights from Japan Consortium for Glycobiology and Glycotechnology", Springer, N. Taniguchi, T. Endo editors, 152-153 (2019)
  2. Shino Manabe, "Anti-diabetes Drug" in "Glycoscience Application and Basic Science: Insights from Japan Consortium for Glycobiology and Glycotechnology", Springer, N. Taniguchi, T. Endo editors, 164 (2019)
  3. Shino Manabe," Heparinoid" in "Glycoscience Application and Basic Science: Insights from Japan Consortium for Glycobiology and Glycotechnology", Springer, N. Taniguchi, T. Endo editors, 176 (2019)
  4. 眞鍋史乃、「バイオ医薬品の開発と市場 2019」「抗体-薬物複合体開発の動向」シーエムシー出版、11-22 (2018)
  5. 眞鍋史乃、「抗体-薬物複合体」「未来を創るグライコサイエンス 我が国のロードマップ」 日本糖鎖科学コンソーシアム編、谷口直之、遠藤玉夫、西原祥子、平林淳、門松健治、秋吉一成、木下-青木F聖子編集、30-32 (2018)
  6. 眞鍋史乃、「ヘパリノイド」「未来を創るグライコサイエンス 我が国のロードマップ」 日本糖鎖科学コンソーシアム編、谷口直之、遠藤玉夫、西原祥子、平林淳、門松健治、秋吉一成、木下-青木F聖子編集、38 (2018)
  7. 眞鍋史乃、「抗糖尿病薬」「未来を創るグライコサイエンス 我が国のロードマップ」 日本糖鎖科学コンソーシアム編、谷口直之、遠藤玉夫、西原祥子、平林淳、門松健治、秋吉一成、木下-青木F聖子編集、131 (2018)
  8. 眞鍋史乃、「抗体薬物複合体(ADC)の設計とDDS技術」「DDS 先端技術の製剤への応用開発」宮崎 巧編、(株)技術情報協会、75-84 (2017)
  9. Shino Manabe, “Conversion of stereochemistry” in “Carbohydrate Chemistry: Proven Methods” Vol. 4, Paul V. Murphy ed. CRC-press, Markus Blaukopf, 19-23 (2017)
  10. 眞鍋史乃、安永正浩、松村保広、「抗体薬物複合体で使用されるリンカーの機能とタイプ」「次世代のがん治療・診断のための研究開発?免疫療法・遺伝子治療・がん幹細胞」菅原 隆編、(株)技術情報協会出版、104-110 (2016)
  11. 眞鍋史乃、「抗体-抗がん剤複合体におけるリンカーテクノロジー」「抗体薬物複合体 (ADC) の設計開発」、松村保広編、シーエムシー出版、31-42 (2016)
  12. 眞鍋史乃、「立体選択的グリコシル化合成」「糖鎖の新機能開発・応用ハンドブック?創薬・医療からヘルスケアまで」秋吉一成、津本浩平、加藤晃一、鷹羽武史、深瀬浩一、古川鋼一編、エヌ・ティー・エス出版、307-309 (2015)
  13. Shino Manabe, “1,2-cis aminoglycoside” in “Glycoscience: Biology and Medicine”, Eds. Taniguchi Naoyuki, Endo Tamao, Gerard Hart, Peter Seeberger, Chi-Huey Wong, Springer, 359-363 (2015)
  14. Yoshito Ihara, Yoko Inai, Midori Ikezaki, In-Sook L. Matsui, Shino Manabe, Yukishige Ito, “C-Mannosylation: a modification on tryptophan in cellular proteins” in “Glycoscience: Biology and Medicine”, Eds. Taniguchi Naoyuki, Endo Tamao, Gerard Hart, Peter Seeberger, Chi-Huey Wong, Springer, 1091-1099 (2015)
  15. Shino Manabe, “1,2-Anhydro mannose” in “Carbohydrate Chemistry: Proven Methods” Vol. 2, Paul Kovac, G. van der Marel. J. Codee eds, CRC-press, Qingju Zhang, Yukishige Ito, 234?238 (2013) doi.10.1016/S0076-6879(10)78020-4
  16. Yasuhiro Matsumura, Masahiro Yasunaga, Shino Manabe, “Cancer stromal targeting (CAST) therapy and tailored antibody drug conjugate therapy depending on the nature of tumor stroma” in “Cancer Targeted Drug Delivery: An Elusive Dream”, You Han Bae, Mrsny Randell, Park Kinam eds, New York Heidelberg Dordrecht London, 161-181 (2013)
  17. 安永正浩、眞鍋史乃、松村保広、「抗間質抗体を利用したがん標的治療」、「ドラッグデリバリーシステムの新展開Ⅱ-核酸医薬・抗体医薬・ワクチン医療を支えるDDS 技術-」永井恒司、岡田弘晃監修、シーエムシー出版、136-148 (2012)
  18. Shino Manabe, “The synthesis of 1,2-cis-amino containing oligosaccharides toward biological investigation” Methods in Enzymology 478, Academic Press, 413-435 (2010)
  19. Yoshito Ihara, Shino Manabe, Yukishige Ito, “C-mannosyl tryptophan: from chemistry to cell biology”, in “Comprehensive Glycoscience, IV” Johannis P. Karmerling, Gert. J. Boons, Yuan Chan Lee, Akemi Suzuki, Naoyuki Taniguchi, A. G. J. Voragen eds. Elsevier, 229-248 (2007)
  20. Yukishige Ito, Shino Manabe, “Polymer supported oligosaccharide synthesis and related technologies”, in “Comprehensive Glycoscience I”, Johannis P. Karmerling, Gert. J. Boons, Yuan Chan Lee, Akemi Suzuki, Naoyuki Taniguchi, A. G. J. Voragen eds. Elsevier, 335-378 (2007)
  21. 眞鍋史乃、伊藤幸成、「有機合成手法による糖鎖迅速合成」、「糖鎖科学の新展開?機能解明・次世代型材料・医薬品開発に向けて」、谷口直之、伊藤幸成監修、株式会社エヌ・ティ・エス、386-392 (2005)
  22. 眞鍋史乃、伊藤幸成、「糖タンパク質、迅速固相反応、新反応」、「未来を拓く糖鎖科学」、永井克孝監修、金芳堂、126-129 (2005)
  23. Yukishige Ito, Shino Manabe, “Synthetic studies on oligosaccharide portions of enediyne antibiotics”, in “Glycoscience III”, Bert Fraser-Reid, Kuniaki Tatsuta, Joachim Thiem eds. Springer, 2441-2467 (2002)

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