Laboratory of Molecular Transformation, Graduate School of Pharmaceutical Sciences, Tohoku University

2023年

  • ● LiO-t-Bu/CsF mediated formal hydrolysis of trifluoromethyl arenes
    Masanori Shigeno*, Moe Kiriyama , Koki Izumi , Keita Sasaki , Ozora Sasamoto , Kanako Nozawa-Kumada , Yoshinori Kondo
    Synthesis, accepted


    ● Copper-Catalyzed Intramolecular Olefinic C(sp2)–H Amidation for the Synthesis of γ-Alkylidene-γ-lactams
    Kanako Nozawa-Kumada*, Masahito Hayashi, Eunsang Kwon, Masanori Shigeno, Akira Yada, and Yoshinori Kondo
    Molecules, 2023, 28, 6682.


    ● Defluorinative Transformation of (2,2,2-Trifluoroethyl)arenes Catalyzed by the Phosphazene Base t-Bu-P2
    Masanori Shigeno*, Yoshiteru Shishido, Amane Soga, Kanako Nozawa-Kumada, and Yoshinori Kondo*
    J. Org. Chem. 2023, 88, 1796–1802.


    ● Transition-Metal-FreeIntermolecular Hydrocarbonation of Styrenes Mediated by NaH/1,10-Phenanthroline
    Kanako Nozawa-Kumada*, So Onuma, Kanako Ono,Tomohiro Kumagai, Yuki Iwakawa, Katsuhiko Sato, Masanori Shigeno, and Yoshinori Kondo*
    Chem. Eur. J. 2023, e202203143.


    ● LiHMDS-Mediated Deprotonative Coupling of Toluenes with Ketones
    Masanori Shigeno*, Akihisa Kajima, Eito Toyama, Toshinobu Korenaga, Hiroyuki Yamakoshi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
    Chem. Eur. J. 2023, 29, e2022035.


    2022年

    • ● 1,5-Double-carboxylation of 2-alkylheteroarenes mediated by a combined Brønsted-base system
      Masanori Shigeno*, Itsuki Tohara, Kanako Nozawa-Kumada, and Yoshinori Kondo*
      Synlett 2022, 33, A–E.


      ● Palladium-Catalyzed Borylative Cyclizations of α-(2-Bromoaryl) Ketones to Form 1,2-Benzoxaborinines
      Masanori Shigeno*, Yuto Iseya, Ryotaro Kume, Kanako Nozawa-Kumada, and Yoshinori Kondo*
      Org. Lett. 2022, 24, 7227-7231.


      ● Combined Brønsted Base-Promoted CO2 Fixation into Benzylic C–H Bonds of Alkylarenes
      Masanori Shigeno*, Itsuki Tohara, Keita Sasaki, Kanako Nozawa-Kumada, and Yoshinori Kondo*
      Org. Lett. 2022, 24, 4825-4830.


      ● Organic superbase t-Bu-P4-catalyzed demethylations of methoxyarenes
      Masanori Shigeno*, Kazutoshi Hayashi, Toshinobu Korenaga*, Kanako Nozawa-Kumada, and Yoshinori Kondo*
      Org. Chem. Front. 2022, 9, 3656-3663.
      Selected as a cover picture


      ● Copper-catalyzed aerobic benzylic C(sp3)–H lactonization of 2-alkylbenzamides via N-centered radicals
      Kanako Nozawa-Kumada,* Kanako Ono, Satoshi Kurosu, Masanori Shigeno, and Yoshinori Kondo*
      Org. Biomol. Chem. 2022, 20, 5948-5952.
      Invited contribution to a New Talent web themed issue


      ● Direct C–H Carboxylation Forming Polyfunctionalized Aromatic Carboxylic Acids by Combined Brønsted Bases
      Masanori Shigeno*, Kazuya Hanasaka, Itsuki Tohara, Koki Izumi, Hiroyuki Yamakoshi, Eunsang Kwon, Kanako Nozawa-Kumada, and Yoshinori Kondo
      Org. Lett. 2022, 3, 809-814.


      2021年

      • ● Construction of 1,2,3-Benzodiazaborole by Electrophilic Borylation of Azobenzene and Nucleophilic Dialkylative Cyclization
        Masanori Shigeno*, Masaya Imamatsu, Yusuke Kai, Moe Kiriyama, Shintaro Ishida, Kanako Nozawa-Kumada, and Yoshinori Kondo
        Org. Lett. 2021, 23, 8023-8027.


        ● Regio- and Stereoselective Hydroiodination of Internal Alkynes with ex Situ Generated HI
        Kanako Nozawa-Kumada,* Koto Noguchi, Tomoya Akada, Masanori Shigeno, and Yoshinori Kondo*
        Org. Lett. 2021, 23, 6659-6663.
        Selected as a cover picture
        Highlighted in organic chemistry portal


        ● Chemical reduction of Ag+ to Ag employing organic electron donors: evaluation of the effect of Ag+-mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles
        Takenori Dairaku,* Rika Kawai, Kanako Nozawa-Kumada, Kentaro Yoshida, Tetsuya Ono, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka and Yoshitomo Kashiwagi*
        Dalton Trans. 2021, 50, 12208-12214.


        ● KO-t-Bu Catalyzed Thiolation of β-(Hetero)arylethyl Ethers via MeOH Elimination/hydrothiolation
        Masanori Shigeno,* Yoshiteru Shishido, Kazutoshi Hayashi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
        Eur. J. Org. Chem. 2021, 3932-3935.


        ● Effect of cytosine–Ag+–cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene
        Takenori Dairaku,* Rika Kawai, Teppei Kanaba, Tetsuya Ono, Kentaro Yoshida, Hajime Sato, Kanako Nozawa-Kumada, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka* and Yoshitomo Kashiwagi*
        Dalton Trans. 2021, 50, 7633-7639.


        ● Copper-catalyzed aerobic double functionalization of benzylic C(sp3)−H bonds for the synthesis of 3-hydroxyisoindolinones
        Kanako Nozawa-Kumada,* Yuta Matsuzawa, Kanako Ono, Masanori Shigeno, and Yoshinori Kondo*
        Chem. Commun. 2021, 57, 8604-8607.


        ● Combined Brønsted-Base-Mediated Direct C-H Carboxylation of Heteroarenes with CO2
        Masanori Shigeno,* Keita Sasaki, Kazuya Hanasaka, Itsuki Tohara, Kanako Nozawa-Kumada, and Yoshinori Kondo*
        Heterocycles 2021, 103, 592-608.


        ● Catalytic amide base system generated in situ for 1,3-diene formation from allylbenzenes and carbonyls
        Masanori Shigeno,* Akihisa Kajima, Kunihito Nakaji, Kanako Nozawa-Kumada, and Yoshinori Kondo*
        Org. Biomol. Chem. 2021, 19, 983-987.
        Selected as a cover picture


        2020年

        • ● Di-tert-butyl Peroxide (DTBP)-Mediated Oxysilylation of Unsaturated Carboxylic Acids for the Synthesis of Silyl Lactones
          Kanako Nozawa-Kumada,* Takuto Ojima, Moeto Inagi, Masanori Shigeno, and Yoshinori Kondo*
          Org. Lett. 2020, 22, 9591-9596.


          ● Catalytic C(sp2)–C(sp3) Bond Formation of Methoxyarenes by the Organic Superbase t-Bu-P4
          Masanori Shigeno,* Kazutoshi Hayashi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
          Org. Lett. 2020, 22, 9107-9113.


          ● NaH-mediated direct C–H arylation in the presence of 1,10-phenanthroline
          Kanako Nozawa-Kumada,* Yuki Iwakawa, So Onuma, Masanori Shigeno, and Yoshinori Kondo*
          Chem. Commun.2020, 56, 7773-7776.


          ● Direct C‐2 carboxylation of 3‐substituted‐indoles using a combined Brønsted base consisting of LiO‐t‐Bu/CsF/18‐crown‐6
          Masanori Shigeno,* Itsuki Tohara, Kanako Nozawa-Kumada, and Yoshinori Kondo*
          Eur. J. Org. Chem.2020, 1987-1991.
          Highlighted in Synfacts, 2020, 16, 0638


          ● Transition‐Metal‐Free Trifluoromethylation of Benzyl Bromides Using Trifluoromethyltrimethylsilane and CsF in 1,2‐Dimethoxyethane
          Kanako Nozawa-Kumada,* Sayuri Osawa, Takuto Ojima, Koto Noguchi, Masanori Shigeno, and Yoshinori Kondo*
          Asian J. Org. Chem.2020, 9, 765-768.
          Invited contribution to a special issue: 100th Annual Meeting of the Chemical Society of Japan


          ● Copper‐Catalyzed Oxidative Benzylic C(sp3)–H Cyclization for the Synthesis of β‐Lactams
          Kanako Nozawa-Kumada,* Satoshi Saga, Yuta Matsuzawa, Masahito Hayashi, Masanori Shigeno, and Yoshinori Kondo*
          Chem. Eur. J.2020, 26, 4496-4499.


          2019年

          • ● Super electron donor-mediated reductive desulfurization reactions
            Kanako Nozawa-Kumada,* Shungo Ito, Koto Noguchi, Masanori Shigeno, and Yoshinori Kondo*
            Chem. Commun.2019, 55, 12968–12971.


            ● Deprotonative Coupling of Pyridines with Aldehydes Catalyzed by an HMDS-amide Base Generated in Situ
            Masanori Shigeno,* Kunihito Nakaji, Akihisa Kajima, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Chem. Pharm. Bull.2019, 67, 1179-1182.


            ● Tetramethylammonium Fluoride Tetrahydrate-Mediated Transition Metal-Free Coupling of Aryl Iodides with Unactivated Arenes in Air
            Kanako Nozawa-Kumada,* Kosuke Nakamura, Satoshi Kurosu, Yuki Iwakawa, Charline Denneval, Masanori Shigeno, and Yoshinori Kondo*
            Chem. Pharm. Bull.2019, 67, 1042–1045.


            ● Catalytic Amination of β-(Hetero)arylethyl Ethers by Phosphazene Base t-Bu-P4
            Masanori Shigeno,* Ryutaro Nakamura, Kazutoshi Hayashi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Org. Lett.2019, 21, 6695–6699.


            ● Organic Superbase t-Bu-P4 Catalyzes Amination of Methoxy(hetero)arenes
            Masanori Shigeno,* Kazutoshi Hayashi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Org. Lett.2019, 21, 5505–5508.


            ● Catalytic alkynylation of polyfluoroarenes by amide base generated in situ
            Masanori Shigeno,* Takuya Okawa, Masaya Imamatsu, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Chem. Eur. J. 2019, 25, 10294–10297.
            Selected as a Hot Paper


            ● 遷移金属触媒および系内発生塩基を利用した炭素―水素結合官能基化反応の開発
            熊田　佳菜子
            Yakugaku Zasshi 2019,139, 1243–1251.


            ● Double-Carboxylation of Two C–H Bonds in 2-Alkylheteroarenes Using LiO-t-Bu/CsF
            Masanori Shigeno,* Keita Sasaki, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Org. Lett.2019, 21, 4515–4519.


            ● Peroxydisulfate‐Mediated Transition‐Metal‐Free Oxidative C(sp3)–H Bond Lactonization
            Kanako Nozawa-Kumada,* Satoshi Kurosu, Masanori Shigeno, Yoshinori Kondo*
            Asian J. Org. Chem. 2019, 8, 1080–1083.
            Invited contribution to a special issue: Heterocyclic Chemistry
            Selected as a cover picture
            The top 10% most downloaded papers in 2019


            ● Catalytic Amide–Base System of TMAF and N(TMS)3 for Deprotonative Coupling of Benzylic C(sp3)–H Bonds with Carbonyls
            Masanori Shigeno,* Kunihito Nakaji, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Org. Lett.2019, 21, 2588–2592.
            One of the Most Read Articles in Org. Lett., April 2019.


          • ● Phosphazene base t‐Bu‐P4‐catalyzed methoxy−alkoxy exchange reaction on (hetero)arenes
            Masanori Shigeno,* Kazutoshi Hayashi, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Chem. Eur. J. 2019, 25, 6077–6081.
            Selected as a cover picture
            Selected as a Hot Topic: Organocatalysis


          • ● Direct Carboxylation of Electron‐Rich Heteroarenes Promoted by LiO‐tBu with CsF and [18]Crown‐6
            Masanori Shigeno,* Kazuya Hanasaka, Keita Sasaki, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Chem. Eur. J. 2019, 25, 3235–3239.
            Selected as a Hot Paper
            The top 10% most downloaded papers in 2019


          • ● Catalytic Deprotonative α-Formylation of Heteroarenes by an Amide Base Generated In Situ from TMAF and N(TMS)3
            Masanori Shigeno,* Yuki Fujii, Akihisa Kajima, Kanako Nozawa-Kumada, and Yoshinori Kondo*
            Org. Process Res. Dev. 2019, 23, 443–451.


            • 2018年

            • ● Construction of Biaryl Scaffolds from Iodoarenes and C−H Heteroarenes Using an Amide Base Generated in situ from Aminosilane and Fluoride Anion
              Masanori Shigeno,* Yusuke Kai, Tetsuya Yamada, Kazutoshi Hayashi, Kanako Nozawa-Kumada, Charline Denneval, and Yoshinori Kondo*
              Asian J. Org. Chem. 2018, 7, 2082–2086.


            • ● Generation and Characterization of Anti-phenyl Sulfate Monoclonal Antibodies and a Potential Use for Phenyl Sulfate Analysis in Human Blood
              Yoshitomi Kanemitsu, Hiroki Tsukamoto*, Yotaro Matsumoto, Kanako Nozawa-Kumada, Yoshinori Kondo, Takaaki Abe, and Yoshihisa Tomioka*
              Biol. Pharm. Bull. 2018, 41, 1170–1177.


            • ● Super Electron Donor-mediated Reductive Transformation of Nitrobenzenes: A Novel Strategy to Synthesize Azobenzenes and Phenazines
              Kanako Nozawa-Kumada, Erina Abe, Shungo Ito, Masanori Shigeno and Yoshinori Kondo*
              Org. Biomol. Chem. 2018, 16, 3095–3098.


              • 2017年

              • ● NaOPh Mediated Hydroxymethylation of Alkynylsilanes with N-((Trimethylsilyloxy)methyl)phthalimide
                Narumi Asano, Keita Sasaki, Isabelle Chataigner, Masanori Shigeno*, and Yoshinori Kondo*
                Eur. J. Org. Chem. 2017, 46, 6926–6930.

              • ● Deprotonative Silylation of Aromatic C−H Bonds Mediated by a Combination of Trifluoromethyltrialkylsilane and Fluoride
                Kanako Nozawa-Kumada, Sayuri Osawa, Midori Sasaki, Isabelle Chataigner, Masanori Shigeno, and Yoshinori Kondo*
                J. Org. Chem. 2017, 82, 9487–9496.


              • ● Highly chemoselective DMPU-mediated trialkylsilylation of terminal alkynes using trifluoromethyltrialkylsilane
                Kanako Nozawa-Kumada, Moeto Inagi, and Yoshinori Kondo*
                Asian J. Org. Chem. 2017, 6, 63-66.


                • 2016年

                • ● Palladium-Catalyzed Highly Chemoselective Intramolecular C–H Aminocarbonylation of Phenethylamines to Six-Membered Benzolactams
                  Hiroshi Taneda, Kiyofumi Inamoto*, and Yoshinori Kondo*
                  Organic Letters 2016, 18(11), 2712-2715.


                • ● Development of Madelung-Type Indole Synthesis Using Copper-Catalyzed Amidation/Condensation Strategy
                  Masahiro Abe, Charline Denneval, Kanako Nozawa-Kumada, and Yoshinori Kondo*
                  Heterocycles 2016,92, 900-909.
                  　Highlighted in Synfacts 2016, 12(06), 574.


                  • 2015年

                  • ● Direct detection of the mercury-nitrogen bond in the thymine-Hg(II)-thymine base-pair with 199Hg NMR spectroscopy
                    Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Sebera, Daichi Yamanaka, Hiroyuki Otaki,
                    Shoko Kikkawa, Yoshinori Kondo, Ritsuko Katahira, F. Matthias Bickelhaupt,
                    Celia Fonseca Guerra, Akira Ono, Vladimir Sychrovsky, Chojiro Kojima, and Yoshiyuki Tanaka*
                    Chemical Communications 2015, 51(40), 8488-8491.


                  • ● Exploring a DNA sequence for the three-dimensional structure determination of a silver(I)-mediated C-C base pair in a DNA duplex by 1H NMR spectroscopy
                    Takenori Dairaku, Kyoko Furuita, Hajime Sato, Yoshinori Kondo, Chojiro Kojima, Akira Ono, and Yoshiyuki Tanaka*
                    Nucleosides, Nucleotides & Nucleic Acids 2015, 34(12), 877-900.


                  • ● Structures, physicochemical properties, and applications of T-HgII-T, C-AgI-C, and other metallo-base pairs
                    Yoshiyuki Tanaka*, Jiro Kondo, Vladimir Sychrovsky, Jakub Šebera,Takenori Dairaku, Hisao Saneyoshi, Hidehito Urata, Hidetaka Torigoe, and Akira Ono*
                    Chemical Communications 2015, 51(98), 17343-17360.


                  • ● High-resolution crystal structure of AgI-RNA hybrid duplex containing Watson-Crick-like C-AgI-C metallo-base pair
                    Jiro Kondo*, Yoshinari Tada, Takenori Dairaku, Hisao Saneyoshi, Itaru Okamoto, Yoshiyuki Tanaka, and Akira Ono
                    Angewandte Chemie International Edition 2015, 54(45), 13323-13326.


                  • ● Copper-Catalyzed sp3 C−H Aminative Cyclization of 2‑Alkyl‑N‑arylbenzamides: An Approach for the Synthesis of N‑Arylisoindolinones
                    　Kanako Nozawa-Kumada, Jun Kadokawa, Takehiro Kameyama, and Yoshinori Kondo*
                    　Organic Letters 2015, 17(4), 4479-4481. 　Highlighted in ChemInform 2017, 47(5).


                  • ● Deprotonative C–H Silylation of Functionalized Arenes and Heteroarenes Using Trifluoromethyltrialkylsilane with Fluoride
                    　Midori Sasaki and Yoshinori Kondo*
                    　Organic Letters 2015, 17(4), 848-851.


                    • 2014年

                    • ● Use of Tetramethylammonium Fluoride (TMAF) and Alkali Metal Alkoxides as an Activator for Catalytic Deprotonative Functionalization of Heteroaromatic C(sp2)-H Bonds
                      　Kiyofumi Inamoto,* Hitomi Okawa, Shoko Kikkawa, and Yoshinori Kondo,*
                      　Tetrahedron, 7917-7922 (2014)


                    • ● Direct condensation of functionalized sp3 carbons with formanilides for enamine synthesis using in situ generated HMDS amide catalyst
                      　Hiroshi Taneda, Kiyofumi Inamoto and Yoshinori Kondo*
                      　Chemical Communications, 6523-6525 (2014)


                    • ● Crystal structure of metallo-DNA duplex containing consecutive Watson-Crick-like T-Hg(II)-T base pairs.
                      　Jiro Kondo*, Tom Yamada, Chika Hirose, Itaru Okamoto, Yoshiyuki Tanaka, Akira Ono,
                      　Angewandte Chemie International Edition, 53, 2385-2388 (2014) (DOI: 10.1002/anie.201309066 and 10.1002/ange.201309066).


                    • ● The structure of metallo-DNA with consecutive T-HgII-T base-pairs explains positive entropy for the metallo-base-pair formation
                      　Hiroshi Yamaguchi, Jakub Sebera, Jiro Kondo, Shuji Oda, Tomoyuki Komuro, Takuya Kawamura, Takenori Daraku, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Jaroslav V. Burda, Chojiro Kojima, Vladimir Sychrovsky,* Yoshiyuki Tanaka,*
                      　Nucleic Acids Research, 42, 4094-4099 (2014) (DOI: 10.1093/nar/gkt1344).


                    • ● Pseudoknot interaction-mediated activation of type I hammerhead ribozyme: A new class of gene-therapeutic agents
                      　Mituhiro Kuriyama, Yoshinori Kondo, and Yoshiyuki Tanaka,*
                      　Nucleosides, Nucleotides & Nucleic Acids, 466-480 (2014) (DOI: 10.1080/15257770.2014.887098).


                    2013年

                    • ● Synthesis of Heterocyclic Compounds through Palladium-Catalyzed C-H Cyclization Processes (review)
                      　Kiyofumi Inamoto,*
                      　Chemical and Pharmaceutical Bulletin 2013, 61(10), 987-996.


                    • ● "Facile deprotection of dithioacetals by using a novel 1,4-benzoquinone/cat. NaI system"
                      　Kiyofumi Inamoto,* Tetsuya Yamada, Sei-ichi Kato, Shoko Kikkawa, and Yoshinori Kondo*
                      　Tetrahedron 2013, 69(44), 9192-9199.


                    • ● "Ruthenium-Catalyzed Carbonylative C-H Cyclization of 2-Arylphenols: A Novel Synthetic Route to 6H-Dibenzo[b,d]pyran-6-ones"
                      　Kiyofumi Inamoto,* Jun Kadokawa, and Yoshinori Kondo*
                      　Organic Letters 2013, 15(15), 3962-3965.
                      　Highlighted in Synfacts 2013, 9(11), 1154.


                    • ● "Organocatalytic Functionalization of Heteroaromatic N-Oxides with C-Nucleophiles Using in situ Generated Onium Amide 　Bases"
                      　Kiyofumi Inamoto,* Yuta Araki, Shoko Kikkawa, Misato Yonemoto, Yoshiyuki Tanaka, and Yoshinori Kondo*
                      Organic & Biomolecular Chemistry 2013, 11(27), 4438-4441.


                    • ● "Carboxylation of Alkynylsilanes with Carbon Dioxide Mediated by Cesium Fluoride in DMSO"
                      　Misato Yonemoto-Kobayashi, Kiyofumi Inamoto, Yoshiyuki Tanaka, and Yoshinori Kondo*
                      　Organic & Biomolecular Chemistry 2013, 11(23), 3773-3775.


                    • ● "Crystal structure of metallo-DNA duplex containing consecutive Watson-Crick-like T-Hg(II)-T base pairs."
                      　Jiro Kondo*, Tom Yamada, Chika Hirose, Itaru Okamoto, Yoshiyuki Tanaka, Akira Ono,
                      　Angewandte Chemie International Edition in press (DOI: 10.1002/anie.201309066 and 10.1002/ange.201309066).


                    • ● "The structure of metallo-DNA with consecutive T-HgII-T base-pairs explains positive entropy for the metallo-base-pair formation"
                      　Hiroshi Yamaguchi, Jakub Sebera, Jiro Kondo, Shuji Oda, Tomoyuki Komuro, Takuya Kawamura, Takenori Daraku, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Jaroslav V. Burda, Chojiro Kojima, Vladimir Sychrovsky,* Yoshiyuki Tanaka,*
                      　Nucleic Acids Research, in press (DOI: 10.1093/nar/gkt1344).


                    • ● "Formation of the T-HgII-T Metal-Mediated DNA Base Pair; Proposal and Theoretical Calculation of the Reaction Pathway."
                      　Jakub Sebera, Jaroslav Burda, Michal Straka, Akira Ono, Chojiro Kojima, Yoshiyuki Tanaka, Vladimir Sychrovsky,*
                      　Chemistry - A European Journal, 19, 9884-9894 (2013).


                    2012年

                  • ● "Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury."
                    　Tomomi Uchiyama, Takashi Miura, Hideo Takeuchi, Takenori Dairaku, Tomoyuki Komuro, Takuya Kawamura, Yoshinori Kondo, Ladislav Benda, Vladimir Sychrovsky,* Petr Bour, Itaru Okamoto,* Akira Ono and Yoshiyuki Tanaka,*
                    　Nucleic Acids Research, 40, 5766-5774 (2012).


                  • ● "Structure Formation and Catalytic Activity of DNA Dissolved in Organic Solvents."
                    　Hiroshi Abe,* Naoko Abe, Aya Shibata, Keiji Ito, Yoshiyuki Tanaka, Mika Ito, Hisao Saneyoshi, Satoshi Shuto, and Yoshihiro Ito,
                    　Angewandte Chemie International Edition, 51, 6475-6479 (2012).


                  • ● "Site-specific isotope labeling of long RNA for structural and mechanistic studies."
                    　Ikumi Kawahara, Kaichiro Haruta,* Yuta Ashihara, Daichi Yamanaka, Mituhiro Kuriyama, Naoko Toki, Yoshinori Kondo, Kenta Teruya, Junya Ishikawa, Hiroyuki Furuta, Yoshiya Ikawa, Chojiro Kojima, Yoshiyuki Tanaka,*
                    　Nucleic Acids Research, 40, e7 (2012).


                  • ● "Organocatalytic Deprotonative Functionalization of C(sp2)-H and C(sp3)-H Bonds Using in situ Generated Onium Amide Bases"
                    　Kiyofumi Inamoto,* Hitomi Okawa, Hiroshi Taneda, Maomi Sato, Yutaro Hirono, Misato Yonemoto, Shoko Kikkawa, and Yoshinori Kondo*
                    　Chemical Communications 2012, 48(78), 9771-9773.


                  • ● "Efficient Use of a Surfactant for Copper-Catalyzed Coupling Reaction of Arylboronic Acids with Imidazoles in Water"
                    　Kiyofumi Inamoto,* Kanako Nozawa, Jun Kadokawa, and Yoshinori Kondo*
                    　Tetrahedron 2012, 68(38), 7794-7798.


                  • ● "Synthesis of 3-Carboxylated Indoles through a Tandem Process Involving Cyclization of 2-Ethynylanilines Followed by CO2 Fixation in the Absence of Transition Metal Catalysts"
                    　Kiyofumi Inamoto,* Narumi Asano, Yuka Nakamura, Misato Yonemoto, and Yoshinori Kondo*
                    　Organic Letters 2012, 14(10), 2622-2625.
                    　Highlighted in Synfacts2012, 8(8), 841.


                  • ● "Palladium-Catalyzed C-H Cyclization in Water: A Milder Route to 2-Arylbenzothiazoles"
                    　Kiyofumi Inamoto,* Kanako Nozawa, and Yoshinori Kondo*
                    　Synlett 2012, 23(11), 1678-1682.


                  • ● "A Highly Sensitive Fluorescence Method Reveals the Presence of Palladium in a Cross-Coupling Reaction Mixture Not Treated with Transition Metals"
                    　Kiyofumi Inamoto,* Laura D. Campbell, Takayuki Doi, and Kazunori Koide*
                    　Tetrahedron Letters 2012, 53(25), 3147-3148.


                  • ● "Tandem-Type Pd(II)-Catalyzed Oxidative Heck Reaction/Intramolecular C-H Amidation Sequence: A Novel Route to 4-Aryl-2-Quinolinones"
                    　Kiyofumi Inamoto,* Junpei Kawasaki, Kou Hiroya, Yoshinori Kondo, and Takayuki Doi*
                    　Chemical Communications 2012, 48(36), 4332-4334.
                    　Highlighted in Synfacts 2012, 8(6), 601.


                  • ● "Use of Dimethyl Carbonate as a Solvent Greatly Enhances the Biaryl Coupling of Aryl Iodides and Organoboron Reagents without Adding Any Transition Metal Catalysts"
                    　Kiyofumi Inamoto,* Chisa Hasegawa, Kou Hiroya, Yoshinori Kondo, Takao Osako, Yasuhiro Uozumi, and Takayuki Doi*
                    　Chemical Communications 2012, 48(23), 2912-2914.


                  • ● "A Copper-Based Catalytic System for Carboxylation of Terminal Alkynes: Synthesis of Alkyl 2-Alkynoates"
                    　Kiyofumi Inamoto,* Narumi Asano, Koji Kobayashi, Misato Yonemoto, and Yoshinori Kondo*
                    　Organic & Biomolecular Chemistry 2012, 10(8), 1514-1516.


                  • ● "Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N-glycosidic Bond of 8-OxoG with the hOGG1 DNA Repair Protein."
                    　Jakub Sebera, Lukas Trantirek, Yoshiyuki Tanaka, and Vladimir Sychrovsky,*
                    　Journal of Physical Chemistry B, 116, 12535-12544 (2012).


                  • ● "Detection of Mercury-TpT Dinucleotide Binding by the Raman Spectra. A Computational Study."
                    　Ladislav Benda, Michal Straka, Vladimir Sychrovsky, Petr Bour,* Yoshiyuki Tanaka,
                    　Journal of Physical Chemistry A, 116, 8313-8320 (2012).


                  • ● "Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C-Ag-C metal-mediated base pair."
                    　Hidetaka Torigoe,* Itaru Okamoto, Takenori Dairaku, Yoshiyuki Tanaka, Akira Ono, T. Kozasa,
                    　Biochimie, 94, 2431-2440 (2012).


                  2011年

                  • ● "Micellar System in Copper-Catalysed Hydroxylation of Arylboronic Acids: Facile Access to Phenols"
                    　Kiyofumi Inamoto,* Kanako Nozawa, Misato Yonemoto, and Yoshinori Kondo*
                    　Chemical Communications, 2011, 47(42), 11775-11777.


                  • ● "Micellar System in Copper-Catalysed Hydroxylation of Arylboronic Acids: Facile Access to Phenols"
                    　Kiyofumi Inamoto,* Kanako Nozawa, Misato Yonemoto, and Yoshinori Kondo*
                    　Chemical Communications, 2011, 47(42), 11775-11777.


                  • ● "Functionalization of Heteroaromatic N-Oxides Using Organic Superbase Catalyst"
                    　Yuta Araki, Koji Kobayashi, Misato Yonemoto, and Yoshinori Kondo*
                    　Organic & Biomolecular Chemistry, 2011, 9(1), 78-80.


                  • ●"Binding of metal ions by pyrimidine base pairs in DNA duplexes."
                    　Akira Ono,* Hidetaka Torigoe, Yoshiyuki Tanaka and Itaru Okamoto,
                    　Chemical Society Reviews, 40, 5855-5866(2011).


                  • ● "Role of Mercury in the Non-Covalent Stabilisation of Consecutive U-HgII-U Metal-Mediated Nucleic Acid Base Pairs: Metallophilic Attraction Enters the World of Nucleic Acids."
                    　Ladislav Benda, Michal Straka,* Yoshiyuki Tanaka, and Vladimir Sychrovsky,*
                    　Physical Chemistry Chemical Physics, 13(1), 100-103(2011).