宇田川 剛 助教 業績
- Udagawa, T.#*, Seki, M.#, Okuyama, T.#, Adachi, S., Natsume, T., Noguchi, T., Matsuzawa, A.,
Inada, T.* (#Equal contribution)
Failure to degrade CAT-tailed proteins disrupts neuronal morphogenesis and cell survival.
Cell Rep. doi: 10.1016/j.celrep.2020.108599 (2021) - Matsuo, Y., Ikeuchi, K., Saeki, Y., Iwasaki, S., Schmidt, C., Udagawa, T., Sato, F., Tsuchiya, H., Becker, T., Tanaka, K., Ingolia, NT., Beckmann, R. and Inada, T.*
Ubiquitination of Stalled Ribosome Triggers Ribosome-associated Quality Control.
Nat. Commun. DOI 10.1038/s41467-017-00188-1 (2017) - Udagawa, T.*, Fujioka, Y.*, Tanaka, M., Honda, D., Yokoi, S, Riku, Y., Ibi, D., Nagai, T., Yamada, K., Watanabe, H., Katsuno, M., Inada, T., Ohno, K., Sokabe, M., Okado, H., Ishigaki, S., Sobue, G.
FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization.
Nat. Commun. 6, 7098.(2015) IF: 10.742 -
Riku, Y., Watanabe, H., Yoshida, M., Tatsumi, S., Mimuro, M., Iwasaki, Y., Katsuno, M., Iguchi, Y., Masuda, M., Senda, J., Ishigaki, S., Udagawa, T., Sobue, G.
Lower Motor Neuron Involvement in TAR DNA-Binding Protein of 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.
JAMA Neurol. 71(2), 172-9. (2014) IF: 7.685 -
Honda, D., Ishigaki, S., Iguchi, Y., Fujioka, Y., Udagawa, T., Masuda, A., Ohno, K., Katsuno, M., Sobue ,G.
The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons.
FEBS Open Bio. 4, 1-10 (2013) IF: 未発表 -
Udagawa, T.*, Farny, N.G.*, Jacovcevski, M.*, Kaphzan, H., Alarcon, J.M., Anilkumar, S., Ivshina, M., Hurt, J., Nagaoka, K., Nalavadi, V.C., Lorenz, L.J., Bassell, G.J., Akbarian, S., Chattarji, S., Klann, E., and Richter, J.D.
Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology.
Nat. Med. 19(11): 1473-7. (2013) IF: 24.302 -
Nemoto, N., Udagawa, T., Chowdhury, W., Kitabatake, M., Shin, B.S., Hiraishi, H., Wang, S., Singh, C.R., Brown, S.J., Ohno, M., and Asano, K.
Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function.
Translation (2013) eLocation ID: e26402 IF: 未発表 -
Fujioka, Y., Ishigaki, S., Masuda, A., Iguchi, Y., Udagawa, T., Watanabe, H., Katsuno, M., Ohno, K., and Sobue, G.
FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD.
Sci. Rep. 3, 2388. (2013) IF: 2.927 -
Hiraishi, H., Shin, B.S., Udagawa, T., Nemoto, N., Chowdhury, W., Graham, J., Cox, C., Reid, M., Brown S.J., and Asano, K.
Interaction between 25S rRNA A loop and eukaryotic translation initiation factor 5B promotes subunit joining and ensures stringent AUG selection.
Mol. Cell Biol. 33(18), 3540-8. (2013) IF: 5.372 -
Oruganty-Das, A., Ng, T., Udagawa, T., Goh, E.L., and Richter, J.D.
Translational control of mitochondria energy production mediates neuron morphogenesis.
Cell Metab. 16(6), 789-800. (2012) IF: 14.619 -
D’Ambrogio, A., Gu, W., Udagawa, T., Mello, C.C., and Richter, J.D.
Specific mRNA stabilization by Gld2-catalyzed monoadenylation.
Cell Rep. 2(6), 1537-45. (2012) IF: 未発表 -
Udagawa, T.*, Swanger, S.A.*, Takeuchi, K., Kim, J.H., Nalavadi, V., Lorenz, L.J., Zukin, R.S., Bassell, G.J., and Richter, J.D.
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.
Mol. Cell 47(2), 253-66. (2012) IF: 15.280 -
Nagaoka, K., Udagawa, T., and Richter, J.D.
CPEB-mediated ZO-1 mRNA localization is required for epithelial tight-junction assembly and cell polarity.
Nat. Commun. 3, 675. (2012) IF: 10.015 -
Nemoto, N. *, Udagawa, T. *, Ohira, T. *, Jiang, L., Hirota, K., Wilkinson, C.R., Bähler J., Jones, N., Ohta, K., Wek, R.C., and Asano, K.
Stress-activated Sty1 and Gcn2 kinases and proto-oncoprotein homologue Int6/eIF3e promotes responses to endogenous oxidative stress during histidine starvation.
J. Mol. Biol. 404(2), 183-202. (2010) IF: 3.905 -
Nemoto, N. *, Singh, C.R. *, Udagawa, T. *, Wang, S. *, Thorson, E., Winter, Z., Ohira, T., Ii, M., Valasek, L., Brown, S.J., and Asano, K.
Yeast 18S rRNA is directly involved in the ribosomal response to stringent AUG selection during translation initiation.
J. Biol. Chem. 285(42), 32200-12. (2010) IF: 4.651 -
Udagawa, T. *, Nemoto, N. *, Wilkinson, C.R., Narashimhan, J., Jiang, L., Watt, S., Zook, A., Jones, N., Wek, R.C., Bähler J., and Asano, K.
Int6/eIF3e promotes general translation and Atf1 abundance to modulate Sty1 MAPK-dependent Stress response in fission yeast.
J. Biol. Chem. 283(32), 22063-75. (2008) IF: 4.651 -
Lee, B., Udagawa, T., Singh, C.R., and Asano, K.
Yeast phenotypic assays on translational control.
Methods Enzymol. 429, 105-37. (2007) IF: 2.002 -
Singh, C.R. *, Udagawa, T.*, Lee, B. *, Wassink, S., He, H., Yamamoto, Y., Anderson J.T., Pavitt, G.D., and Asano K.
Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo.
J. Mol. Biol. 370(2), 315-30. (2007) IF: 3.905 -
Singh, C.R.*, Lee, B.*, Udagawa, T., Mohammad-Qureshi, S.S., Yamamoto, Y., Pavitt, G.D., and Asano, K.
A novel eIF5/eIF2 complex antagonizes guanine nucleotide exchange and multifactor complex assembly.
EMBO J. 25(19), 4537-46. (2006) IF: 9.822 -
Fukuhara, T., Koga, R., Aoki, N., Yuki, C., Yamamoto, N., Oyama, N., Udagawa, T., Horiuchi, H., Miyazaki, S., Higashi, Y., Takeshita, M., Ikeda, K., Arakawa, M., Matsumoto, N. & Moriyama, H.
The wide distribution of endornaviruses, large double-stranded RNA replicons with plasmid-like properties.
Arch. Virol. 151(5), 995-1002. (2006) IF: 2.030 -
Udagawa T., Shimizu Y., and Ueda T.
Evidence for the translation initiation of leaderless mRNAs by the intact 70S ribosome without its dissociation into subunits in eubacteria.
J. Biol. Chem. 279(10), 8539-46. (2004) IF: 4.651 -
Horiuchi H., Udagawa T., Koga R., Moriyama H., and Fukuhara T.
RNA-dependent RNA polymerase activity associated with endogenous double-stranded RNA in rice.
Plant Cell Physiol. 42(2), 197-203. (2001) IF: 4.134
